Search Results - "Pfitzner, E"
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1
Near-field magneto-caloritronic nanoscopy on ferromagnetic nanostructures
Published in AIP advances (01-12-2018)“…Near-field optical microscopy by means of infrared photocurrent mapping has rapidly developed in recent years. In this letter we introduce a near-field induced…”
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2
The role of STATs in inflammation and inflammatory diseases
Published in Current pharmaceutical design (01-01-2004)“…The immune response is regulated by the concerted action of pro- and anti-inflammatory cytokines. The deregulation of this process causes immunological…”
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3
Newly found sunspot observations by Peter Becker from Rostock for 1708, 1709, and 1710
Published in Astronomische Nachrichten (01-09-2015)“…We present a few newly found old sunspot observations from the years AD 1708, 1709, and 1710, which were obtained by Peter Becker from Rostock, Germany. For…”
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4
STAT6 and STAT1 are essential antagonistic regulators of cell survival in classical Hodgkin lymphoma cell line
Published in Leukemia (01-10-2009)“…Classical Hodgkin lymphoma (cHL) is a malignant lymphoid disorder characterized by aberrant activation of signaling pathways. Constitutive activation of…”
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Transcription linked to recombination : a gene-internal promoter coincides with the recombination hot spot II of the human MLL gene
Published in Oncogene (01-03-2007)“…The MLL gene is frequently involved in chromosomal translocations associated with high-risk acute leukaemia. Infant and therapy-related acute leukaemia…”
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6
p300/CREB-Binding Protein Enhances the Prolactin-Mediated Transcriptional Induction through Direct Interaction with the Transactivation Domain of Stat5, but Does Not Participate in the Stat5-Mediated Suppression of the Glucocorticoid Response
Published in Molecular endocrinology (Baltimore, Md.) (01-10-1998)“…Stat5 was discovered as a PRL-induced member of the Stat (signal transducer and activator of transcription) family. Its induction by many other cytokines and…”
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7
Persistent STAT3 Activation in Colon Cancer Is Associated with Enhanced Cell Proliferation and Tumor Growth
Published in Neoplasia (New York, N.Y.) (01-06-2005)“…Colorectal carcinoma (CRC) is a major cause of morbidity and mortality in Western countries. It has so far been molecularly defined mainly by alterations of…”
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p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6
Published in Nucleic acids research (01-07-1999)“…Interleukin-4 (IL-4) induces tyrosine phosphorylation of the latent transcription factor Stat6, which mediates the transcriptional responses of IL-4. The…”
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9
Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family
Published in Journal of steroid biochemistry and molecular biology (01-04-1999)“…The pathways which connect extracellular signals with the regulation of the activity of transcription factors are being investigated in molecular detail…”
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Journal Article Conference Proceeding -
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Regulation of the trans-activation potential of STAT5 through its DNA-binding activity and interactions with heterologous transcription factors
Published in Growth hormone & IGF research (01-04-2000)“…Extracellular hormones, growth factors and cytokines relay their effects on the transcription of genes through the recognition of specific receptors and…”
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11
Functional Antagonism Between the Retinoic Acid Receptor and the Viral Transactivator BZLF1 is Mediated by Protein-Protein Interactions
Published in Proceedings of the National Academy of Sciences - PNAS (19-12-1995)“…The Epstein-Barr virus-encoded protein BZLF1 is a member of the basic leucine zipper (bZip) family of transcription factors. Like several other members of the…”
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12
Acetylation of Stat1 modulates NF-κB activity
Published in Genes & development (15-02-2006)“…Acetylation of signaling molecules can lead to apoptosis or differentiation of carcinoma cells. The molecular mechanisms underlying these processes and the…”
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Specific function of STAT3, SOCS1, and SOCS3 in the regulation of proliferation and survival of classical Hodgkin lymphoma cells
Published in International journal of cancer (15-03-2006)“…The essential regulators in the pathogenesis of classical Hodgkin lymphoma (cHL) are still largely unknown. The malignant Hodgkin/Reed–Sternberg (HRS) cells of…”
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14
Structure of the Unphosphorylated STAT5a Dimer
Published in The Journal of biological chemistry (09-12-2005)“…STAT proteins have the function of signaling from the cell membrane into the nucleus, where they regulate gene transcription. Latent mammalian STAT proteins…”
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15
Recombinant activation domains of virion protein 16 and human estrogen receptor generate transcriptional interference in vitro by distinct mechanisms
Published in Molecular endocrinology (Baltimore, Md.) (01-08-1993)“…Overexpression of transcriptional activators in transfection assays may inhibit their own activity or interfere with trans-activation by different…”
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Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells
Published in The international journal of biochemistry & cell biology (01-11-2005)“…Extravillous trophoblast cells resemble cancer cells with regard to their intrinsic invasiveness. They invade decidual tissue, but, unlike tumor cells, shut…”
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NCoA-1/SRC-1 Is an Essential Coactivator of STAT5 That Binds to the FDL Motif in the α-Helical Region of the STAT5 Transactivation Domain
Published in The Journal of biological chemistry (14-11-2003)“…Signal transducer and activator of transcription 5 (STAT5) is a transcription factor that activates prolactin (PRL)-dependent gene expression in the mammary…”
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18
Transcriptional Activation by STAT6 Requires the Direct Interaction with NCoA-1
Published in The Journal of biological chemistry (07-12-2001)“…Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation…”
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An LXXLL Motif in the Transactivation Domain of STAT6 Mediates Recruitment of NCoA-1/SRC-1
Published in The Journal of biological chemistry (27-09-2002)“…Signal transducer and activator of transcription 6 (STAT6) regulates transcriptional activation in response to interleukin-4 (IL-4)-induced tyrosine…”
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Journal Article -
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Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain
Published in Journal of molecular biology (13-02-2004)“…Signal transducer and activator of transcription 6 (STAT6) regulates transcriptional activation in response to interleukin-4 (IL-4) by direct interaction with…”
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