Search Results - "Pfister, Dominik"
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The immunological and metabolic landscape in primary and metastatic liver cancer
Published in Nature reviews. Cancer (01-09-2021)“…The liver is the sixth most common site of primary cancer in humans, and generally arises in a background of cirrhosis and inflammation. Moreover, the liver is…”
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Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
Published in Nature medicine (01-04-2019)“…Non-alcoholic fatty liver disease ranges from steatosis to non-alcoholic steatohepatitis (NASH), potentially progressing to cirrhosis and hepatocellular…”
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XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis
Published in Nature Medicine (01-06-2021)“…Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are prevalent liver conditions that underlie the development of…”
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Characteristics of children and adolescents at the Switzerland-wide first ambulatory interdisciplinary pain clinic at the University Children's Hospital Basel - a retrospective study
Published in Swiss medical weekly (08-04-2019)“…Given the long history of underestimating chronic pain in children and adolescents, we lack valid data on its assessment and treatment. The psychological and…”
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Age-Related Gliosis Promotes Central Nervous System Lymphoma through CCL19-Mediated Tumor Cell Retention
Published in Cancer cell (16-09-2019)“…How lymphoma cells (LCs) invade the brain during the development of central nervous system lymphoma (CNSL) is unclear. We found that NF-κB-induced gliosis…”
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Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
Published in Nature medicine (01-03-2022)Get full text
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Publisher Correction: XCR1+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis
Published in Nature Medicine (2022)“…In the version of this Article initially published, an electronic conversion error led to errors in the names of Michal Safran and Baoguo Li. Their names have…”
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L-Selectin/CD62L is a Key Driver of Non-Alcoholic Steatohepatitis in Mice and Men
Published in Cells (Basel, Switzerland) (29-04-2020)“…CD62L (L-Selectin) dependent lymphocyte infiltration is known to induce inflammatory bowel disease (IBD), while its function in the liver, especially in…”
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The immunology of hepatocellular carcinoma
Published in Nature immunology (01-03-2018)“…In contrast to most other malignancies, hepatocellular carcinoma (HCC), which accounts for approximately 90% of primary liver cancers, arises almost…”
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THU-248 Unraveling the interplay of FGF21 and GLP1 analogue in metabolic dysfunction-associated steatohepatitis in vivo
Published in Journal of hepatology (01-06-2024)Get full text
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NASH limits anti-tumour surveillance in immunotherapy-treated HCC
Published in Nature (London) (15-04-2021)“…Hepatocellular carcinoma (HCC) can have viral or non-viral causes 1 – 5 . Non-alcoholic steatohepatitis (NASH) is an important driver of HCC. Immunotherapy has…”
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Somatostatin receptor expression related to TP53 and RB1 alterations in pancreatic and extrapancreatic neuroendocrine neoplasms with a Ki67-index above 20
Published in Modern pathology (01-04-2017)“…Somatostatin receptor 2A expression is a feature of well-differentiated neuroendocrine neoplasms and is important for their diagnosis and therapy. Little is…”
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Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH
Published in Nature (London) (15-04-2021)“…Nonalcoholic steatohepatitis (NASH) is a manifestation of systemic metabolic disease related to obesity, and causes liver disease and cancer 1 , 2 . The…”
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XCR1.sup.+ type 1 conventional dendritic cells drive liver pathology in non-alcoholic steatohepatitis
Published in Nature medicine (01-06-2021)“…Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are prevalent liver conditions that underlie the development of…”
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Auto-aggressive CXCR6.sup.+ CD8 T cells cause liver immune pathology in NASH
Published in Nature (London) (15-04-2021)“…Nonalcoholic steatohepatitis (NASH) is a manifestation of systemic metabolic disease related to obesity, and causes liver disease and cancer.sup.1,2. The…”
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Publisher Correction: Inhibition of LT[beta]R signalling activates WNT-induced regeneration in lung
Published in Nature (London) (21-01-2021)“…A Correction to this paper has been published:…”
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An Immune Gene Expression Signature Associated With Development of Human Hepatocellular Carcinoma Identifies Mice That Respond to Chemopreventive Agents
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2019)“…Cirrhosis and chronic inflammation precede development of hepatocellular carcinoma (HCC) in approximately 80% of cases. We investigated immune-related gene…”
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Inhibition of LTβR signalling activates WNT-induced regeneration in lung
Published in Nature (London) (03-12-2020)“…Lymphotoxin β-receptor (LTβR) signalling promotes lymphoid neogenesis and the development of tertiary lymphoid structures 1 , 2 , which are associated with…”
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Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling
Published in Journal of hepatology (01-08-2023)“…The progression of non-alcoholic steatohepatitis (NASH) to fibrosis and hepatocellular carcinoma (HCC) is aggravated by auto-aggressive T cells. The gut-liver…”
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