Search Results - "Pfeiffer, E S"
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Mice with Conditional Inactivation of Fibroblast Growth Factor Receptor-2 Signaling in Oligodendrocytes Have Normal Myelin But Display Dramatic Hyperactivity when Combined with Cnp1 Inactivation
Published in The Journal of neuroscience (22-11-2006)“…Fibroblast growth factor receptors (Fgfr) comprise a widely expressed family of developmental regulators implicated in oligodendrocyte (OL) maturation of the…”
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2
Antibody Cross-Linking of Myelin Oligodendrocyte Glycoprotein Leads to Its Rapid Repartitioning into Detergent-Insoluble Fractions, and Altered Protein Phosphorylation and Cell Morphology
Published in The Journal of neuroscience (02-07-2003)“…Myelin oligodendrocyte glycoprotein (MOG) is, quantitatively, a relatively minor component of the myelin membrane. Nevertheless, peritoneal administration of…”
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3
Differential myelinogenic capacity of specific developmental stages of the oligodendrocyte lineage upon transplantation into hypomyelinating hosts
Published in Journal of neuroscience research (01-01-1993)“…The capacity of oligodendrocytes (OLs) and their progenitors to migrate, proliferate, and differentiate in vivo was evaluated by transplanting highly enriched…”
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4
Multiple and novel specificities of monoclonal antibodies O1, O4, and R-mAb used in the analysis of oligodendrocyte development
Published in Journal of neuroscience research (01-12-1989)“…Three monoclonal antibodies that react with antigens on the surface of developing oligodendrocytes in a stage-specific manner, O1, O4 (Sommer and Schachner,…”
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5
Proligodendroblast antigen (POA), a developmental antigen expressed by A007/O4-positive oligodendrocyte progenitors prior to the appearance of sulfatide and galactocerebroside
Published in Journal of neurochemistry (01-06-1992)“…Evidence is presented for the immunological identification of a developmental antigen appearing at a critical point in the oligodendroglial lineage…”
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6
FGF-2 converts mature oligodendrocytes to a novel phenotype
Published in Journal of neuroscience research (15-10-1997)“…Fibroblast growth factor (FGF)‐2 differentially regulates oligodendrocyte progenitor proliferation and differentiation in culture, and modulates gene…”
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7
Cloning and characterization of MVP17: a developmentally regulated myelin protein in oligodendrocytes
Published in Journal of neuroscience research (15-10-1995)“…The remarkable quantities of myelin membrane produced by oligodendrocytes has led us to examine the mechanisms involved in the sorting and transport of…”
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Proliferation and differentiation of O4+ oligodendrocytes in postnatal rat cerebellum: analysis in unfixed tissue slices using anti-glycolipid antibodies
Published in Journal of neuroscience research (01-10-1992)“…We report the study of the in vivo morphology, differentiation, and proliferation of oligodendrocytes (OLs) and their progenitors identified by the…”
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9
Inhibition of Protein and Lipid Sulfation in Oligodendrocytes Blocks Biological Responses to FGF-2 and Retards Cytoarchitectural Maturation, but Not Developmental Lineage Progression
Published in Developmental biology (01-04-1994)“…We have examined the interfaces between protein and lipid sulfation, the response of progenitor cells to specific growth factors, and developmental lineage…”
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10
SNARE complex proteins, including the cognate pair VAMP-2 and syntaxin-4, are expressed in cultured oligodendrocytes
Published in Journal of neurochemistry (01-03-1999)“…Myelin membrane synthesis in the CNS by oligodendrocytes (OLs) involves directed intracellular transport and targeting of copious amounts of specialized lipids…”
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11
Oligodendrocyte progenitors isolated directly from developing telencephalon at a specific phenotypic stage: myelinogenic potential in a defined environment
Published in Development (Cambridge) (01-05-1989)“…Oligodendroglia differentiate asynchronously in the developing central nervous system, passing through a series of stages identified by the sequential…”
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12
Astroglial control of oligodendrocyte survival mediated by PDGF and leukemia inhibitory factor-like protein
Published in Development (Cambridge) (01-07-1995)“…Programmed death and the identification of growth factors delaying this process in the oligodendrocyte lineage suggest that other cell types provide…”
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13
Glial Cell Mitogens bFGF and PDGF Differentially Regulate Development of O4+GalC- Oligodendrocyte Progenitors
Published in Developmental biology (01-10-1993)“…The oligodendrocyte lineage in cerebrum is characterized by the expression of immunologically identified surface antigens resulting in the sequential…”
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14
Novel stage in the oligodendrocyte lineage defined by reactivity of progenitors with R-mAb prior to O1 anti-galactocerebroside
Published in Journal of neuroscience research (01-07-1992)“…The developmentally regulated appearance of surface immuno-reactivity of proligodendroblasts [oligodendrocyte progenitors reacting with monoclonal antibodies…”
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15
Reversible Inhibition of Oligodendrocyte Progenitor Differentiation by a Monoclonal Antibody against Surface Galactolipids
Published in Proceedings of the National Academy of Sciences - PNAS (01-08-1989)“…We have hypothesized that oligodendrocyte (OL) surface glycolipids, specifically galactocerebroside and sulfatide, play a role in the regulation of OL…”
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16
Regulation of FGF Receptors in the Oligodendrocyte Lineage
Published in Molecular and cellular neuroscience (01-04-1996)“…Fibroblast growth factors (FGFs) affect a broad spectrum of developmentally regulated cellular responses involved in the control of growth and differentiation…”
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17
Monoclonal autoantibody SCH94.03, which promotes central nervous system remyelination, recognizes an antigen on the surface of oligodendrocytes
Published in Journal of neuroscience research (01-02-1996)“…A monoclonal antibody SCH94.03, made in syngeneic mice by injection of spinal cord homogenate, promotes central nervous system remyelination when injected into…”
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18
Transient reversion of O4+ GalC- oligodendrocyte progenitor development in response to the phorbol ester TPA
Published in Journal of neuroscience research (01-01-1993)“…The physiological importance of protein kinase C during oligodendrocyte progenitor maturation was investigated by analyzing the effects of the protein kinase C…”
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19
TPO1, a Member of a Novel Protein Family, Is Developmentally Regulated in Cultured Oligodendrocytes
Published in Journal of neurochemistry (01-10-1997)“…: Although the myelin membrane contains only a small set of major proteins, more sensitive assays indicate the presence of a plethora of uncharacterized…”
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Regulation of gene expression in mature oligodendrocytes by the specialized myelin-like membrane environment: antibody perturbation in culture with the monoclonal antibody R-mAb
Published in Glia (01-11-1994)“…We have previously shown that the growth of oligodendrocyte progenitors in the presence of a monoclonal antibody (R-mAb) reacting with a cell surface component…”
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