Search Results - "Pfarr, Curt M."

Transcriptional Activity of CCAAT/Enhancer-binding Proteins Is Controlled by a Conserved Inhibitory Domain That Is a Target for Sumoylation by Kim, Jinyong, Cantwell, Carrie A., Johnson, Peter F., Pfarr, Curt M., Williams, Simon C.

“…CCAAT/enhancer-binding proteins (C/EBPs) are basic region/leucine zipper transcription factors that function as regulators of cell growth and differentiation…”
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A c-jun dominant negative mutant protects sympathetic neurons against programmed cell death by Ham, Jonathan, Babij, Carol, Whitfield, Jonathan, Pfarr, Curt M, Lallemand, Dominique, Yaniv, Moshe, Rubin, Lee L

“…Sympathetic neurons depend on nerve growth factor (NGF) for survival and die by apoptosis in its absence. We have investigated the pattern of expression of the…”
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Transformation by ras modifies AP1 composition and activity by MECHTA, F, LALLEMAND, D, PFARR, C. M, YANIV, M

“…The Ras proteins play a central role in regulating cell growth and their mutation can lead to abnormal proliferation. To analyse the potential link betwen AP1…”
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Regulation of Two JunD Isoforms by Jun N-terminal Kinases by Yazgan, Oya, Pfarr, Curt M.

“…The JunD transcription factor is one member of the Jun family of proteins that also includes c-Jun and JunB. Although c-Jun can function to promote cell…”
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Translational Regulation of the JunD Messenger RNA by Short, John D., Pfarr, Curt M.

“…JunD, a member of the Jun family of nuclear transcription proteins, dimerizes with Fos family members or other Jun proteins (c-Jun or JunB) to form the…”
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Analysis of Pre-clerkship Medical Students’ Perceptions and Performance During the COVID-19 Pandemic by Ayoubieh, Houriya, Alkhalili, Eyas, Nino, Diego, Coue, Martine, Herber-Valdez, Christiane, Pfarr, Curt M.

“…Purpose Virtual instruction became the primary educational delivery method for pre-clerkship medical students during the COVID-19 pandemic. The aims of this…”
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Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts by LALLEMAND, D, SPYROU, G, YANIV, M, PFARR, C. M

“…We have analysed the different Jun and Fos proteins as NIH3T3 fibroblasts pass from exponential growth to quiescence and during the first 24 h after their…”
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Personalized Medicine in Undergraduate Medical Education: a Spiral Learning Model by Chacon, Jessica A., Cervantes, Jorge L., Perry, Cynthia N., Pfarr, Curt M., Ayoubieh, Houriya

“…Educational strategies to introduce medical students to scientific advances are needed as evidence continues to evolve regarding their clinical application in…”
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Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras by Pfarr, C M, Mechta, F, Spyrou, G, Lallemand, D, Carillo, S, Yaniv, M

“…As NIH 3T3 fibroblasts become quiescent, the level of c-Jun protein decreases while JunD accumulates. When resting cells are stimulated with fresh serum,…”
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Differential binding of the Menin tumor suppressor protein to JunD isoforms by YAZGAN, Oya, PFARR, Curt M

“…The role of the Jun family of proteins (c-Jun, JunB, and JunD) in oncogenesis has been extensively studied, but the distinct biological roles of each Jun…”
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Stress-activated protein kinases are negatively regulated by cell density by Lallemand, Dominique, Ham, Jonathan, Garbay, Serge, Bakiri, Latifa, Traincard, François, Jeannequin, Odile, Pfarr, Curt M., Yaniv, Moshe

“…Stimulation by UV irradiation, TNFα, as well as PDGF or EGF activates the JNK/SAPK signalling pathway in mouse fibroblasts. This results in the phosphorylation…”
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Requirement of an Upstream AP-1 Motif for the Constitutive and Phorbol Ester-inducible Expression of the Urokinase-type Plasminogen Activator Receptor Gene by Lengyel, E, Wang, H, Stepp, E, Juarez, J, Wang, Y, Doe, W, Pfarr, C M, Boyd, D

“…The urokinase-type plasminogen activator receptor (u-PAR) facilitates extracellular matrix proteolysis by accelerating plasmin formation at the cell surface…”
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A Scholarly Activity and Research Requirement at the Paul L. Foster School of Medicine by Pfarr, Curt M., Lacy, Naomi L., Coue, Martine

“…The Paul L. Foster School of Medicine (PLFSOM) is the newest of nine allopathic medical schools located in Texas, welcoming its inaugural class in 2010. The…”
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A Laboratory for Education in Molecular Medicine: a Dedicated Resource for Medical Student Research by Pfarr, Curt M., Bramblett, Debra, Osborne, David, Trott, Amy, Balsiger, Heather, Coue, Martine, Brower, Richard, Hogg, Tanis

“…The Paul L. Foster School of Medicine in El Paso, Texas seated its inaugural class in 2009 and introduced a highly-integrated pre-clinical curriculum that…”
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Stepwise transformation of rat embryo fibroblasts: c-Jun, JunB, or JunD can cooperate with Ras for focus formation, but a c-Jun-containing heterodimer is required for immortalization by Vandel, Laurence, Montreau, Nicole, Vial, Emmanuel, Pfarr, Curt M., Binetruy, Bernard, Castellazzi, Marc

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mitotic Motors by McIntosh, J. Richard, Pfarr, Curt M.

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The glucocorticoid receptor and AP-1 are involved in a positive regulation of the muscle regulatory gene myf5 in cultured myoblasts by Auradé, F, Pfarr, C M, Lindon, C, Garcia, A, Primig, M, Montarras, D, Pinset, C

“…The muscle regulatory factor, myf5, is involved in the establishment of skeletal muscle precursor cells. Little is known, however, about the control of the…”
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Cyclic AMP stimulates a JunD/Fra-2 AP-1 complex and inhibits the proliferation of interleukin-6-dependent cell lines by Rezzonico, R, Loubat, A, Lallemand, D, Pfarr, C M, Far, D F, Proudfoot, A, Rossi, B, Ponzio, G

“…Interleukin-6 (IL-6) is a proinflammatory cytokine which also acts as a growth factor for some murine hybridomas (7TD1) or human myelomas (U266). We…”
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Increased transforming activity of JunB and JunD by introduction of an heterologous homodimerization domain by Vandel, L, Pfarr, C M, Huguier, S, Loiseau, L, Sergeant, A, Castellazzi, M

“…The closely-related proteins c-Jun, JunB and JunD form a family of transcription factors which require dimerization for DNA-binding and transcriptional…”
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Stepwise transformation of rat embryo fibroblasts : c-Jun, JunB, or JunD can cooperate with Ras for focus formation, but a c-Jun-containing heterodimer is required for immortalization by Vandel, Laurence, Montreau, Nicole, Vial, Emmanuel, Pfarr, Curt M., Binetruy, Bernard, Castellazzi, Marc

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