Search Results - "Pfaller, Monika"
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Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation
Published in Journal of molecular medicine (Berlin, Germany) (01-06-2022)“…Aquaporin-4 (AQP4) is the molecular target of the immune response in neuromyelitis optica (NMO) that leads to severe structural damage in the central nervous…”
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The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the TH17 lineage in humans
Published in Proceedings of the National Academy of Sciences - PNAS (23-08-2022)“…Although glioblastoma multiforme (GBM) is not an invariably cold tumor, checkpoint inhibition has largely failed in GBM. In order to investigate T…”
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Siponimod Hinders the Formation of meningeal Ectopic Lymphoid Tissue in a Mouse Model of Multiple Sclerosis (4204)
Published in Neurology (14-04-2020)“…Abstract only…”
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Formation and immunomodulatory function of meningeal B-cell aggregates in progressive CNS autoimmunity
Published in Brain (London, England : 1878) (28-07-2021)“…Meningeal B lymphocyte aggregates have been described in autopsy material of patients with chronic Multiple Sclerosis. The presence of meningeal B cell…”
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IL-24 intrinsically regulates Th17 cell pathogenicity in mice
Published in The Journal of experimental medicine (01-08-2022)“…In certain instances, Th17 responses are associated with severe immunopathology. T cell–intrinsic mechanisms that restrict pathogenic effector functions have…”
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Phylogeography of the littoral prawn species Palaemon elegans (Crustacea: Caridea: Palaemonidae) across the Mediterranean Sea unveils disparate patterns of population genetic structure and demographic history in the two sympatric genetic types II and III
Published in Marine biodiversity (01-12-2018)“…In this study, we examine the spatial distribution of genetic diversity of the littoral prawn species complex Palaemon elegans across the Mediterranean, with…”
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The glioblastoma multiforme tumor site promotes the commitment of tumor-infiltrating lymphocytes to the T H 17 lineage in humans
Published in Proceedings of the National Academy of Sciences - PNAS (23-08-2022)“…Although glioblastoma multiforme (GBM) is not an invariably cold tumor, checkpoint inhibition has largely failed in GBM. In order to investigate T…”
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8
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4
Published in Nature (London) (14-03-2024)“…Neuromyelitis optica is a paradigmatic autoimmune disease of the central nervous system, in which the water-channel protein AQP4 is the target antigen 1 . The…”
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Corrigendum to: Formation and immunomodulatory function of meningeal B cell aggregates in progressive CNS autoimmunity
Published in Brain (London, England : 1878) (22-10-2021)Get full text
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Siponimod Inhibits the Formation of Meningeal Ectopic Lymphoid Tissue in Experimental Autoimmune Encephalomyelitis
Published in Neurology : neuroimmunology & neuroinflammation (01-01-2022)“…To investigate whether the formation or retention of meningeal ectopic lymphoid tissue (mELT) can be inhibited by the sphingosine 1-phosphate receptor 1,5…”
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Anti-CD20 Depletes Meningeal B Cells but Does Not Halt the Formation of Meningeal Ectopic Lymphoid Tissue
Published in Neurology : neuroimmunology & neuroinflammation (02-07-2021)“…To investigate whether anti-CD20 B-cell-depleting monoclonal antibodies (ɑCD20 mAbs) inhibit the formation or retention of meningeal ectopic lymphoid tissue…”
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Intrathecally Expanding B Cell Clones in Herpes Simplex Encephalitis: A Case Report
Published in Neurology and therapy (01-06-2022)“…Introduction In spite of antiviral treatment, herpes simplex encephalitis (HSE) remains associated with a poor prognosis and often results in neurological…”
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