Search Results - "Pfaller, K."

Cyclical adaptation of measles virus quasispecies to epithelial and lymphocytic cells: To V, or not to V by Donohue, Ryan C, Pfaller, Christian K, Cattaneo, Roberto

“…Measles virus (MeV) is dual-tropic: it replicates first in lymphatic tissues and then in epithelial cells. This switch in tropism raises the question of…”
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C Proteins: Controllers of Orderly Paramyxovirus Replication and of the Innate Immune Response by Siering, Oliver, Cattaneo, Roberto, Pfaller, Christian K

“…Particles of many paramyxoviruses include small amounts of proteins with a molecular weight of about 20 kDa. These proteins, termed "C", are basic, have low…”
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Guanylate-Binding Proteins 2 and 5 Exert Broad Antiviral Activity by Inhibiting Furin-Mediated Processing of Viral Envelope Proteins by Braun, Elisabeth, Hotter, Dominik, Koepke, Lennart, Zech, Fabian, Groß, Rüdiger, Sparrer, Konstantin M.J., Müller, Janis A., Pfaller, Christian K., Heusinger, Elena, Wombacher, Rebecka, Sutter, Kathrin, Dittmer, Ulf, Winkler, Michael, Simmons, Graham, Jakobsen, Martin R., Conzelmann, Karl-Klaus, Pöhlmann, Stefan, Münch, Jan, Fackler, Oliver T., Kirchhoff, Frank, Sauter, Daniel

“…Guanylate-binding protein (GBP) 5 is an interferon (IFN)-inducible cellular factor reducing HIV-1 infectivity by an incompletely understood mechanism. Here, we…”
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Measles Virus C Protein Impairs Production of Defective Copyback Double-Stranded Viral RNA and Activation of Protein Kinase R by Pfaller, Christian K, Radeke, Monte J, Cattaneo, Roberto, Samuel, Charles E

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Extensive editing of cellular and viral double-stranded RNA structures accounts for innate immunity suppression and the proviral activity of ADAR1p150 by Pfaller, Christian K, Donohue, Ryan C, Nersisyan, Stepan, Brodsky, Leonid, Cattaneo, Roberto

“…The interferon (IFN)-mediated innate immune response is the first line of defense against viruses. However, an IFN-stimulated gene, the adenosine deaminase…”
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Brain tropism acquisition: The spatial dynamics and evolution of a measles virus collective infectious unit that drove lethal subacute sclerosing panencephalitis by Yousaf, Iris, Hannon, William W, Donohue, Ryan C, Pfaller, Christian K, Yadav, Kalpana, Dikdan, Ryan J, Tyagi, Sanjay, Schroeder, Declan C, Shieh, Wun-Ju, Rota, Paul A, Feder, Alison F, Cattaneo, Roberto

“…It is increasingly appreciated that pathogens can spread as infectious units constituted by multiple, genetically diverse genomes, also called collective…”
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Safe and effective two-in-one replicon-and-VLP minispike vaccine for COVID-19: Protection of mice after a single immunization by Hennrich, Alexandru A, Sawatsky, Bevan, Santos-Mandujano, Rosalía, Banda, Dominic H, Oberhuber, Martina, Schopf, Anika, Pfaffinger, Verena, Wittwer, Kevin, Riedel, Christiane, Pfaller, Christian K, Conzelmann, Karl-Klaus

“…Vaccines of outstanding efficiency, safety, and public acceptance are needed to halt the current SARS-CoV-2 pandemic. Concerns include potential side effects…”
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Measles Virus Ribonucleoprotein Complexes Rapidly Spread across Well-Differentiated Primary Human Airway Epithelial Cells along F-Actin Rings by Singh, Brajesh K, Pfaller, Christian K, Cattaneo, Roberto, Sinn, Patrick L

“…Measles virus (MeV) is a highly contagious human pathogen that continues to be a worldwide health burden. One of the challenges for the study of MeV spread is…”
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Trans -endocytosis elicited by nectins transfers cytoplasmic cargo, including infectious material, between cells by Generous, Alex R, Harrison, Oliver J, Troyanovsky, Regina B, Mateo, Mathieu, Navaratnarajah, Chanakha K, Donohue, Ryan C, Pfaller, Christian K, Alekhina, Olga, Sergeeva, Alina P, Indra, Indrajyoti, Thornburg, Theresa, Kochetkova, Irina, Billadeau, Daniel D, Taylor, Matthew P, Troyanovsky, Sergey M, Honig, Barry, Shapiro, Lawrence, Cattaneo, Roberto

“…Here, we show that cells expressing the adherens junction protein nectin-1 capture nectin-4-containing membranes from the surface of adjacent cells in a…”
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Small-molecule polymerase inhibitor protects non-human primates from measles and reduces shedding by Wittwer, Kevin, Anderson, Danielle E., Pfeffermann, Kristin, Cox, Robert M., Wolf, Josef D., Santibanez, Sabine, Mankertz, Annette, Plesker, Roland, Sticher, Zachary M., Kolkykhalov, Alexander A., Natchus, Michael G., Pfaller, Christian K., Plemper, Richard K., von Messling, Veronika

“…Measles virus (MeV) is a highly contagious pathogen that enters the human host via the respiratory route. Besides acute pathologies including fever, cough and…”
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Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output by Rommel, Marcel G.E., Walz, Lisa, Fotopoulou, Foteini, Kohlscheen, Saskia, Schenk, Franziska, Miskey, Csaba, Botezatu, Lacramioara, Krebs, Yvonne, Voelker, Iris M., Wittwer, Kevin, Holland-Letz, Tim, Ivics, Zoltán, von Messling, Veronika, Essers, Marieke A.G., Milsom, Michael D., Pfaller, Christian K., Modlich, Ute

“…Respiratory tract infections are among the deadliest communicable diseases worldwide. Severe cases of viral lung infections are often associated with a…”
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Overcoming the Barrier of the Respiratory Epithelium during Canine Distemper Virus Infection by Shin, Dai-Lun, Chludzinski, Elisa, Wu, Nai-Huei, Peng, Ju-Yi, Ciurkiewicz, Malgorzata, Sawatsky, Bevan, Pfaller, Christian K, Baechlein, Christine, von Messling, Veronika, Haas, Ludwig, Beineke, Andreas, Herrler, Georg

“…Canine distemper virus (CDV) is a highly contagious pathogen and is known to enter the host via the respiratory tract and disseminate to various organs…”
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Measles Virus C Protein Interferes with Beta Interferon Transcription in the Nucleus by SPARRER, Konstantin M. J, PFALLER, Christian K, CONZELMANN, Karl-Klaus

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Genetic Dissection of Interferon-Antagonistic Functions of Rabies Virus Phosphoprotein: Inhibition of Interferon Regulatory Factor 3 Activation Is Important for Pathogenicity by RIEDER, Martina, BRZOZKA, Krzysztof, PFALLER, Christian K, COX, James H, STITZ, Lothar, CONZELMANN, Karl-Klaus

“…Authors' Corrections ( vol. 86 , p. 4720 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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Tissue characterization of the medical fungus Hericium coralloides by focus-variation microscopy by Pallua, J. D., Unterberger, S. H., Pallua, A. F., Pfaller, K., Pallua, A. K., Putzer, D., Pöder, R., Kirchmair, M.

“…In this study, the potential of focus-variation microscopic imaging was evaluated in a study of morphological patterns of the potential medicinal fungus…”
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Staphylococcus aureus biofilm formation and antibiotic susceptibility tests on polystyrene and metal surfaces by Coraça‐Huber, D.C, Fille, M, Hausdorfer, J, Pfaller, K, Nogler, M

“…Aim: We compared the MBEC™‐HTP assay plates made of polystyrene with metal discs composed of TMZF® and CrCo as substrates for biofilm formation. Methods and…”
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Brain resident memory T cells rapidly expand and initiate neuroinflammatory responses following CNS viral infection by Ayasoufi, Katayoun, Wolf, Delaney M., Namen, Shelby L., Jin, Fang, Tritz, Zachariah P., Pfaller, Christian K., Zheng, Jiaying, Goddery, Emma N., Fain, Cori E., Gulbicki, Lauren R., Borchers, Anna L., Reesman, Rachael A., Yokanovich, Lila T., Maynes, Mark A., Bamkole, Michael A., Khadka, Roman H., Hansen, Michael J., Wu, Long-Jun, Johnson, Aaron J.

“…Healthy brain harbors populations of resident memory T cells (TRM). These TRM cells rapidly proliferate in response to CNS insults of various origins…”
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Measles Virus V Protein Is a Decoy Substrate for IκB Kinase α and Prevents Toll-Like Receptor 7/9-Mediated Interferon Induction by Pfaller, Christian K., Conzelmann, Karl-Klaus

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The Measles Virus V Protein Binds to p65 (RelA) To Suppress NF-κB Activity by Schuhmann, Kerstin M., Pfaller, Christian K., Conzelmann, Karl-Klaus

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Morphological and tissue characterization of the medicinal fungus Hericium coralloides by a structural and molecular imaging platform by Pallua, J D, Recheis, W, Pöder, R, Pfaller, K, Pezzei, C, Hahn, H, Huck-Pezzei, V, Bittner, L K, Schaefer, G, Steiner, E, Andre, G, Hutwimmer, S, Felber, S, Pallua, A K, Pallua, A F, Bonn, G K, Huck, C W

“…In this study the potential of new imaging techniques such as Magnetic Resonance Imaging (MRI), Matrix-Assisted Laser Desorption/Ionization (MALDI) profiling…”
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