Search Results - "Pfaff, Martin"

Paxillin phosphorylation controls invadopodia/podosomes spatiotemporal organization by Badowski, Cédric, Pawlak, Géraldine, Grichine, Alexei, Chabadel, Anne, Oddou, Christiane, Jurdic, Pierre, Pfaff, Martin, Albigès-Rizo, Corinne, Block, Marc R

“…In Rous sarcoma virus (RSV)-transformed baby hamster kidney (BHK) cells, invadopodia can self-organize into rings and belts, similarly to podosome distribution…”
Get full text

Binding of paxillin to α4 integrins modifies integrin-dependent biological responses by SHOUCHUN LIU, THOMAS, S. M, WOODSIDE, D. G, ROSE, D. M, KLOSSES, W. B, PFAFF, M, GINSBERG, M. H

Get full text

Suppression of Integrin Activation: A Novel Function of a Ras/Raf-Initiated MAP Kinase Pathway by Hughes, Paul E, Renshaw, Mark W, Pfaff, Martin, Forsyth, Jane, Keivens, Virginia M, Schwartz, Martin A, Ginsberg, Mark H

“…Rapid modulation of ligand binding affinity (“activation”) is a central property of the integrin cell adhesion receptors. Using a screen for suppressors of…”
Get full text

Quantification of patellar tracking using kinematic MRI by Powers, C M, Shellock, F G, Pfaff, M

“…The purpose of this study was to describe a method to quantify dynamic patellar tracking using kinematic MRI (KMRI). Twelve normal females and three patients…”
Get more information

Cell adhesion and integrin binding to recombinant human fibrillin-1 by Pfaff, Martin, Reinhardt, Dieter P., Sakai, Lynn Y., Timpl, Rupert

“…Fibrillin-1 is a major constituent of tissue microfibrils that occur in most connective tissues, either in close association with or independent of elastin. To…”
Get full text

Integrin and Arg-Gly-Asp dependence of cell adhesion to the native and unfolded triple helix of collagen type VI by Pfaff, M, Aumailley, M, Specks, U, Knolle, J, Zerwes, H G, Timpl, R

“…Pepsin-solubilized collagen VI in triple-helical and heat-denatured, unfolded form was shown to promote Mg(2+)- and Mn(2+)-dependent attachment and spreading…”
Get more information

Podosomes in osteoclast-like cells by Pfaff, Martin, Jurdic, Pierre

“…Macrophages and osteoclasts develop unique contact sites with the extracellular matrix called podosomes. Podosomes have been associated with migratory and…”
Get full text

A Genetic Analysis of Integrin Function: Glanzmann Thrombasthenia in vitro by Baker, Elizabeth K., Tozer, Eileen Collins, Pfaff, Martin, Shattil, Sanford J., Loftus, Joseph C., Ginsberg, Mark H.

“…Glanzmann thrombasthenia, an inherited bleeding disorder, can be caused by a defect or deficiency in platelet integrin α IIbβ 3 (GPIIb-IIIa). Studies of…”
Get full text

Integrin affinity modulation by Hughes, Paul E, Pfaff, Martin

“…Integrin cell-adhesion receptors mediate interactions between cells and the extracellular matrix. Dynamic regulation of integrin adhesive function is termed…”
Get full text

Casein kinase II accumulation in the nucleolus and its role in nucleolar phosphorylation by Pfaff, M, Anderer, F A

“…A rabbit antiserum against highly purified casein kinase II from mouse tumor cells was used for immunolocalization of the enzyme in fixed, permeabilized mouse…”
Get more information

Integrin beta cytoplasmic domains differentially bind to cytoskeletal proteins by Pfaff, M, Liu, S, Erle, D J, Ginsberg, M H

“…Integrin cytoplasmic domains connect these receptors to the cytoskeleton. Furthermore, integrin-cytoskeletal interactions involve ligand binding (occupancy) to…”
Get full text

β1 Integrin-Dependent and -Independent Polymerization of Fibronectin by Wennerberg, Krister, Lohikangas, Lars, Gullberg, Donald, Pfaff, Martin, Johansson, Staffan, Fässler, Reinhard

“…The mouse cell line GD25, which lacks expression of the β1 family of integrin heterodimers due to disruption of the β1 integrin subunit gene, was used for…”
Get full text

Pro citizen insurance: "Wages and prices alone should not determine health care" (interview by Prof. Dr. Martin Pfaff) by Pfaff, Martin

Get more information

Lack of β1 Integrin Gene in Embryonic Stem Cells Affects Morphology, Adhesion, and Migration but Not Integration into the Inner Cell Mass of Blastocysts by Fässler, Reinhard, Pfaff, Martin, Murphy, John, Noegel, Angelika A., Johansson, Staffan, Timpl, Rupert, Albrecht, Richard

“…A gene trap-type targeting vector was designed to inactivate the β1 integrin gene in embryonic stem (ES) cells. Using this vector more than 50% of the ES cell…”
Get full text

Calpain cleavage of integrin β cytoplasmic domains by Pfaff, Martin, Du, Xiaoping, Ginsberg, Mark H

“…We showed previously that the calcium-dependent protease, calpain, cleaves the cytoplasmic domain of the integrin β3 subunit. To investigate whether…”
Get full text

Fibrinolytic therapy of St. Jude valve thrombosis under guidance of digital cinefluoroscopy by Czer, Lawrence S.C., Weiss, Mason, Bateman, Timothy M., Martin Pfaff, J., DeRobertis, Michele, Eigler, Neal, Vas, Ran, Matloff, Jack M., Gray, Richard J.

“…Fibrinolytic therapy is an alternative to urgent reoperation for patients with St. Jude prosthetic valve thrombosis, but requires an accurate mejhod for…”
Get full text

Aggregation of mononucleated precursors triggers cell surface expression of αvβ3 integrin, essential to formation of osteoclast-like multinucleated cells by Boissy, Patrice, Machuca, Irma, Pfaff, Martin, Ficheux, Damien, Jurdic, Pierre

“…αvβ3 is a key integrin mediating adhesion of multinucleated osteoclasts during bone resorption. 1,25-dihydroxyvitamin D3 upregulates αvβ3 integrin expression…”
Get full text

Integrin-Binding and Cell-Adhesion Studies of Fibulins Reveal a Particular Affinity for αIIbβ3 by Pfaff, Martin, Sasaki, Takako, Tangemann, Kirsten, Chu, Mon-Li, Timpl, Rupert

“…The extracellular matrix proteins fibulin-1 (variants C and D) and fibulin-2 occur in basement membranes and in vessel walls and are thus potential candidates…”
Get full text

Integrin β Cytoplasmic Domains Differentially Bind to Cytoskeletal Proteins by Martin Pfaff, Shouchun Liu, David J. Erle, Mark H. Ginsberg

“…Integrin cytoplasmic domains connect these receptors to the cytoskeleton. Furthermore, integrin-cytoskeletal interactions involve ligand binding (occupancy) to…”
Get full text

Paxillin Phosphorylation Controls Invadopodia/Podosomes Spatiotemporal Organization: Paxillin phosphorylation and invadopodia dynamics by Badowski, Cédric, Pawlak, Géraldine, Grichine, Alexei, Chabadel, Anne, Oddou, Christiane I., Jurdic, Pierre, Pfaff, Martin, Albiges-Rizo, Corinne, Block, Marc R.

“…In Rous sarcoma virus (RSV)-transformed baby hamster kidney (BHK) cells, invadopodia can self-organize into rings and belts, similarly to podosome distribution…”
Get full text