Search Results - "Pfänder, Pauline"
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Comparative Assessment of Quantification Methods for Tumor Tissue Phosphoproteomics
Published in Analytical chemistry (Washington) (09-08-2022)“…With increasing sensitivity and accuracy in mass spectrometry, the tumor phosphoproteome is getting into reach. However, the selection of quantitation…”
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Cdk5 Deletion Enhances the Anti-inflammatory Potential of GC-Mediated GR Activation During Inflammation
Published in Frontiers in immunology (10-07-2019)“…The suppression of activated pro-inflammatory macrophages during immune response has a major impact on the outcome of many inflammatory diseases including…”
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3
Device-Controlled Microcondensation for Spatially Confined On-Tissue Digests in MALDI Imaging of N-Glycans
Published in Pharmaceuticals (Basel, Switzerland) (03-11-2022)“…On-tissue enzymatic digestion is a prerequisite for MALDI mass spectrometry imaging (MSI) and spatialomic analysis of tissue proteins and their N-glycan…”
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Deletion of Cdk5 in Macrophages Ameliorates Anti-Inflammatory Response during Endotoxemia through Induction of C-Maf and Il-10
Published in International journal of molecular sciences (06-09-2021)“…Immune response control is critical as excessive cytokine production can be detrimental and damage the host. Interleukin-10 (Il-10), an anti-inflammatory…”
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IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression
Published in Cell (03-09-2020)“…Aryl hydrocarbon receptor (AHR) activation by tryptophan (Trp) catabolites enhances tumor malignancy and suppresses anti-tumor immunity. The context…”
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Device-Controlled Microcondensation for Spatially Confined On-Tissue Digests in MALDI Imaging of IN/I-Glycans
Published in Pharmaceuticals (Basel, Switzerland) (01-11-2022)“…On-tissue enzymatic digestion is a prerequisite for MALDI mass spectrometry imaging (MSI) and spatialomic analysis of tissue proteins and their N-glycan…”
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Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma
Published in Theranostics (2021)“…Tryptophan (Trp)-catabolic enzymes (TCEs) produce metabolites that activate the aryl hydrocarbon receptor (AHR) and promote tumor progression and…”
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