Search Results - "Pezzi, Hannah M."
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High Specificity in Circulating Tumor Cell Identification Is Required for Accurate Evaluation of Programmed Death-Ligand 1
Published in PloS one (26-07-2016)“…Expression of programmed-death ligand 1 (PD-L1) in non-small cell lung cancer (NSCLC) is typically evaluated through invasive biopsies; however, recent…”
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2
Using Exclusion-Based Sample Preparation (ESP) to Reduce Viral Load Assay Cost
Published in PloS one (02-12-2015)“…Viral load (VL) measurements are critical to the proper management of HIV in developing countries. However, access to VL assays is limited by the high cost and…”
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Integration of Magnetic Bead-Based Cell Selection into Complex Isolations
Published in ACS omega (30-04-2018)“…Magnetic bead-based analyte capture has emerged as a ubiquitous method in cell isolation, enabling the highly specific capture of target populations through…”
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Versatile exclusion-based sample preparation platform for integrated rare cell isolation and analyte extraction
Published in Lab on a chip (06-11-2018)“…Rare cell populations provide a patient-centric tool to monitor disease treatment, response, and resistance. However, understanding rare cells is a complex…”
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Magnetic System for Automated Manipulation of Paramagnetic Particles
Published in Analytical chemistry (Washington) (18-10-2016)“…The simple, rapid magnetic manipulation of paramagnetic particles (PMPs) paired with the wide range of available surface chemistries has strongly positioned…”
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AirJump: Using Interfaces to Instantly Perform Simultaneous Extractions
Published in ACS applied materials & interfaces (22-06-2016)“…Analyte isolation is an important process that spans a range of biomedical disciplines, including diagnostics, research, and forensics. While downstream…”
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RNA-mediated TILDA for improved cell capacity and enhanced detection of multiply-spliced HIV RNA
Published in Integrative biology (Cambridge) (13-11-2017)“…Quantification of the HIV viral reservoir is critical to understanding HIV latency, advancing patient care and ultimately achieving a cure. To quantify the…”
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HIV Viral RNA Extraction in Wax Immiscible Filtration Assisted by Surface Tension (IFAST) Devices
Published in The Journal of molecular diagnostics : JMD (01-05-2014)“…The monitoring of viral load is critical for proper management of antiretroviral therapy for HIV-positive patients. Unfortunately, in the developing world,…”
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Development of a Highly Sensitive Cell-Based Assay for Detecting Botulinum Neurotoxin Type A through Neural Culture Media Optimization
Published in Journal of biomolecular screening (01-01-2016)“…Botulinum neurotoxin (BoNT) is the most lethal naturally produced neurotoxin. Due to the extreme toxicity, BoNTs are implicated in bioterrorism, while the…”
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10
Exclusion-Based Capture and Enumeration of CD4+ T Cells from Whole Blood for Low-Resource Settings
Published in Journal of Laboratory Automation (01-06-2014)“…In developing countries, demand exists for a cost-effective method to evaluate human immunodeficiency virus patients’ CD4+ T-helper cell count. The TH (CD4)…”
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Abstract B40: Analytical validation and initial clinical utility of multianalyte transcriptomic biomarker profiling of circulating tumor cells using automated exclusion-based sample preparation technology
Published in Clinical cancer research (01-06-2020)“…The efficacy of androgen receptor (AR) signaling inhibitors (ARSIs) in prostate cancer is limited by both de novo and acquired resistance. Two well-described…”
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RNA-mediated TILDA for improved cell capacity and enhanced detection of multiply-spliced HIV RNAElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ib00112f
Published 13-11-2017“…Quantification of the HIV viral reservoir is critical to understanding HIV latency, advancing patient care and ultimately achieving a cure. To quantify the…”
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13
Developing Tools for Interrogation of Clinically Significant Rare Cell Populations
Published 2017“…Rare cell populations are a potential tool for assessing disease progression, treatment, and monitoring while also providing the opportunity for new diagnostic…”
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Dissertation