Search Results - "Pezuk, J. A."

Polo-like kinase 1 inhibition causes decreased proliferation by cell cycle arrest, leading to cell death in glioblastoma by Pezuk, J A, Brassesco, M S, Morales, A G, de Oliveira, J C, de Paula Queiroz, R G, Machado, H R, Carlotti, C G, Neder, L, Scrideli, C A, Tone, L G

“…Glioblastoma (GBM) is one of the most aggressive central nervous system tumors with a patient’s median survival of <1 year. Polo-like kinases (PLKs) are a…”
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PLK1 expression and BI 2536 effects in childhood acute lymphoblastic leukemia by Oliveira, J.C., Pezuk, J.A., Brassesco, M.S., Morales, A.G., Queiroz, R.G.P., Scrideli, C.A., Tone, L.G.

“…Background Polo‐like kinase 1 (PLK1) is a conserved kinase that mediates various mitotic events. Compelling data have repeatedly demonstrated its upregulation…”
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miRNA signatures in childhood sarcomas and their clinical implications by Viera, G. M., Salomao, K. B., de Sousa, G. R., Baroni, M., Delsin, L. E. A., Pezuk, J. A., Brassesco, M. S.

“…Progresses in multimodal treatments have significantly improved the outcomes for childhood cancer. Nonetheless, for about one-third of patients with Ewing…”
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Editorial Expression of Concern: miRNA signatures in childhood sarcomas and their clinical implications by Viera, G. M., Salomao, K. B., de Sousa, G. R., Baroni, M., Delsin, L. E. A., Pezuk, J. A., Brassesco, M. S.

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Technical challenges of working with extracellular vesicles by Ramirez, Marcel I, Amorim, Maria G, Gadelha, Catarina, Milic, Ivana, Welsh, Joshua A, Freitas, Vanessa M, Nawaz, Muhammad, Akbar, Naveed, Couch, Yvonne, Makin, Laura, Cooke, Fiona, Vettore, Andre L, Batista, Patricia X, Freezor, Roberta, Pezuk, Julia A, Rosa-Fernandes, Lívia, Carreira, Ana Claudia O, Devitt, Andrew, Jacobs, Laura, Silva, Israel T, Coakley, Gillian, Nunes, Diana N, Carter, Dave, Palmisano, Giuseppe, Dias-Neto, Emmanuel

“…Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with potential applications in diagnosis, prognosis and therapeutic…”
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Inhibition of NF-κB by Dehydroxymethylepoxyquinomicin Suppresses Invasion and Synergistically Potentiates Temozolomide and γ-Radiation Cytotoxicity in Glioblastoma Cells by Roberto, G. M., Brassesco, María Sol, Morales, A. G., Oliveira, J. C., Delsin, L. E. A., Pezuk, J. A., Valera, E. T., Carlotti Jr., C. G., Rego, E. M., de Oliveira, H. F., Scrideli, Carlos Alberto, Umezawa, K., Tone, Luiz Gonzaga

“…Despite advances in neurosurgery and aggressive treatment with temozolomide (TMZ) and radiation, the overall survival of patients with glioblastoma (GBM)…”
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PEDIATRICS LABORATORY RESEARCH by Brassesco, M. S., Valera, E. T., Pezuk, J. A., Morales, A. G., Oliveira, J. C., Umezawa, K., Rego, E. M., Carlotti, G. C., Scrideli, C. A., Tone, L. G., Adachi, J.-i., Suzuki, T., Yanagisawa, T., Fukuoka, K., Mishima, K., Wakiya, K., Matsutani, M., Nishikawa, R., Fernandez-L, A., Squatrito, M., Northcott, P., Holland, E. C., Taylor, M. D., Nahle, Z., Kenney, A. M., Ashley, D. M., Muscat, A., Gordon, L., Rigby, L., Birks, D., Foreman, N., Algar, E., Donovan, L. K., Potter, N., Warr, T., Pilkington, G., Erdreich-Epstein, A., Zhou, H., Ren, X., Davidson, T. B., Schur, M., Ji, L., Sposto, R., Asgharzadeh, S., Hiddingh, L., Caretti, V., Hulleman, E., Kaspers, G.-J. L., Vandertop, W. P., Noske, D. P., Wurdinger, T., Lagerweij, T., Koken, P. W., Kaspers, G. G., Bar, E. E., Schreck, K., Eberhart, C. G., Largaespada, D. A., Larson, J. D., Rodriquez, F. J., Demer, A. M., Sarver, A. L., Dubuc, A., Jenkins, R. B., Dupuy, A. J., Copeland, N. G., Jenkins, N. A., Taylor, M. A., Monje, M., Freret, M. E., Beachy, P. A., Jansen, M. H., Vandertop, P. W., Dorris, K., Sobo, M., Panditharatna, E., Liu, C., Kim, M.-O., Miles, L., Goldman, S., Gardner, S., Stevenson, C., Maugans, T., Fouladi, M., Drissi, R., Fults, D. W., Mumert, M., Pedone, C. A., Wu, X., Northcott, P. A., Saratsis, A. M., Magge, S., Rood, B., Hill, A., Nazarian, J., van Vuurden, D. G., Bugiani, M., Wesseling, P., Kaspers, G. J., Gopalakrishnan, V.

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BI 2536-mediated PLK1 inhibition suppresses HOS and MG-63 osteosarcoma cell line growth and clonogenicity by Morales, Andressa G, Brassesco, María S, Pezuk, Julia A, Oliveira, Jaqueline C, Montaldi, Ana P, Sakamoto-Hojo, Elza T, Scrideli, Carlos A, Tone, Luiz G

“…Osteosarcoma is the most common primary malignant tumor of bone, which frequently occurs in the second decade of life. Despite the improvements in neoadjuvant…”
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