Search Results - "Pezuk, J."
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miRNA signatures in childhood sarcomas and their clinical implications
Published in Clinical & translational oncology (01-12-2019)“…Progresses in multimodal treatments have significantly improved the outcomes for childhood cancer. Nonetheless, for about one-third of patients with Ewing…”
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Editorial Expression of Concern: miRNA signatures in childhood sarcomas and their clinical implications
Published in Clinical & translational oncology (01-07-2024)Get full text
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Polo-like kinase 1 inhibition causes decreased proliferation by cell cycle arrest, leading to cell death in glioblastoma
Published in Cancer gene therapy (01-09-2013)“…Glioblastoma (GBM) is one of the most aggressive central nervous system tumors with a patient’s median survival of <1 year. Polo-like kinases (PLKs) are a…”
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PLK1 expression and BI 2536 effects in childhood acute lymphoblastic leukemia
Published in Pediatric blood & cancer (01-07-2014)“…Background Polo‐like kinase 1 (PLK1) is a conserved kinase that mediates various mitotic events. Compelling data have repeatedly demonstrated its upregulation…”
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Technical challenges of working with extracellular vesicles
Published in Nanoscale (18-01-2018)“…Extracellular Vesicles (EVs) are gaining interest as central players in liquid biopsies, with potential applications in diagnosis, prognosis and therapeutic…”
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Inhibition of NF-κB by Dehydroxymethylepoxyquinomicin Suppresses Invasion and Synergistically Potentiates Temozolomide and γ-Radiation Cytotoxicity in Glioblastoma Cells
Published in Chemotherapy research and practice (01-01-2013)“…Despite advances in neurosurgery and aggressive treatment with temozolomide (TMZ) and radiation, the overall survival of patients with glioblastoma (GBM)…”
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PEDIATRICS LABORATORY RESEARCH
Published in Neuro-oncology (Charlottesville, Va.) (01-11-2011)Get full text
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BI 2536-mediated PLK1 inhibition suppresses HOS and MG-63 osteosarcoma cell line growth and clonogenicity
Published in Anti-cancer drugs (01-11-2011)“…Osteosarcoma is the most common primary malignant tumor of bone, which frequently occurs in the second decade of life. Despite the improvements in neoadjuvant…”
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