Search Results - "Peytavin, G."
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Dolutegravir-based and low-dose efavirenz-based regimen for the initial treatment of HIV-1 infection (NAMSAL): week 96 results from a two-group, multicentre, randomised, open label, phase 3 non-inferiority trial in Cameroon
Published in The lancet HIV (01-10-2020)“…BACKGROUNDUpdated WHO guidelines recommend a dolutegravir-based regimen as the preferred first-line treatment for HIV infection and low-dose efavirenz (400 mg)…”
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Persistent low-level viraemia in antiretroviral treatment-experienced patients is not linked to viral resistance or inadequate drug concentrations
Published in Journal of antimicrobial chemotherapy (01-10-2020)“…Abstract Objectives To assess genotypic sensitivity scores (GSSs), plasma antiretroviral concentrations (PACs) and immunovirological outcomes at Week 96 (W96)…”
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Letermovir breakthroughs during the French Named Patient Programme: interest of monitoring blood concentration in clinical practice
Published in Journal of antimicrobial chemotherapy (01-08-2020)“…To analyse mechanisms of letermovir breakthrough during compassionate primary and secondary prophylaxis. Mechanisms of letermovir breakthrough during…”
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Dolutegravir as monotherapy in HIV-1-infected individuals with suppressed HIV viraemia
Published in Journal of antimicrobial chemotherapy (01-09-2016)“…Reducing drug burden is a key challenge for achieving lifelong suppressive HIV therapy. Dolutegravir, with a high potency, long half-life and high genetic…”
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Increased mortality in HIV/HCV-coinfected compared to HCV-monoinfected patients in the DAA era due to non-liver-related death
Published in Journal of hepatology (01-01-2021)“…Direct-acting antivirals (DAA) lead to high sustained virological response (SVR) rates and decrease the risk of disease progression. We compared SVR rates and…”
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Comparison of HIV-Infected and Noninfected Patients Undergoing Bariatric Surgery: The ObeVIH Study
Published in Journal of acquired immune deficiency syndromes (1999) (01-06-2022)“…The aim of this study was to compare clinical characteristics and adipose/liver tissue histology analysis in HIV-infected and HIV-uninfected subjects…”
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Prevalence and clinical impact of minority resistant variants in patients failing an integrase inhibitor-based regimen by ultra-deep sequencing
Published in Journal of antimicrobial chemotherapy (01-09-2018)“…Integrase strand transfer inhibitors (INSTIs) are recommended by international guidelines as first-line therapy in antiretroviral-naive and -experienced…”
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Long-term follow-up of HIV-infected patients on dolutegravir monotherapy
Published in Journal of antimicrobial chemotherapy (01-03-2020)“…Abstract Background In recent years, dolutegravir monotherapy has been explored as a drug-reduced regimen for HIV patients. Methods This was a retrospective…”
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Resistance profile and treatment outcomes in HIV-infected children at virological failure in Benin, West Africa
Published in Journal of antimicrobial chemotherapy (01-11-2018)“…In Africa a high percentage of HIV-infected children continue to experience HIV treatment failure despite enormous progress. In Benin (West Africa), there are…”
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Plasma pharmacokinetics of bedaquiline administered by nasogastric tube in an intensive care unit
Published in The international journal of tuberculosis and lung disease (01-01-2020)“…We present the case of a 21-year-old man admitted to the intensive care unit with multi-organ failure due to multidrug-resistant tuberculosis (TB). TB…”
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Safety and Efficacy of Raltegravir in HIV‐Infected Transplant Patients Cotreated with Immunosuppressive Drugs
Published in American journal of transplantation (01-08-2009)“…Solid organ transplantations (SOT) are performed successfully in selected HIV‐infected patients. However, multiple and reciprocal drug–drug interactions are…”
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Placental Transfer of Maraviroc in an Ex Vivo Human Cotyledon Perfusion Model and Influence of ABC Transporter Expression
Published in Antimicrobial Agents and Chemotherapy (01-03-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Pharmacokinetics of dolutegravir in a premature neonate after HIV treatment intensification during pregnancy
Published in Antimicrobial agents and chemotherapy (01-06-2015)“…We describe the pharmacokinetics of dolutegravir (DTG) in a premature neonate after maternal intensification of an antiretroviral (ARV) regimen by adding DTG…”
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Factors associated with the emergence of integrase resistance mutations in patients failing dual or triple integrase inhibitor-based regimens in a French national survey
Published in Journal of antimicrobial chemotherapy (01-09-2021)“…Abstract Background Successful 2-drug regimens (2DRs) for HIV were made possible by the availability of drugs combining potency and tolerability with a high…”
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Long-term plasma pharmacokinetics of bedaquiline for multidrug- and extensively drug-resistant tuberculosis
Published in The international journal of tuberculosis and lung disease (01-01-2019)“…SETTING: Bedaquiline (BDQ) has been approved for the treatment of multidrug- and extensively drug-resistant tuberculosis (MDR/XDR-TB). For many patients…”
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Surveillance of HIV-1 primary infections in France from 2014 to 2016: toward stable resistance, but higher diversity, clustering and virulence?
Published in Journal of antimicrobial chemotherapy (01-01-2020)“…Abstract Objectives Patients with primary HIV-1 infection (PHI) are a particular population, giving important insight about ongoing evolution of transmitted…”
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HIV-2 integrase gene polymorphism and phenotypic susceptibility of HIV-2 clinical isolates to the integrase inhibitors raltegravir and elvitegravir in vitro
Published in Journal of antimicrobial chemotherapy (01-11-2008)“…Objectives We investigated the in vitro phenotypic susceptibility of HIV-2 isolates from integrase inhibitor (INI)-naive patients to INIs and its relation to…”
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Efficacy and safety of dolutegravir and rilpivirine dual therapy as a simplification strategy: a cohort study
Published in HIV medicine (01-10-2017)Get full text
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