Search Results - "Petzold, Christopher"

Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production by Alonso-Gutierrez, Jorge, Chan, Rossana, Batth, Tanveer S., Adams, Paul D., Keasling, Jay D., Petzold, Christopher J., Lee, Taek Soon

“…Limonene is a valuable monoterpene used in the production of several commodity chemicals and medicinal compounds. Among them, perillyl alcohol (POH) is a…”
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Systems and synthetic biology tools for advanced bioproduction hosts by Chen, Yan, Banerjee, Deepanwita, Mukhopadhyay, Aindrila, Petzold, Christopher J

“…The genomic revolution ushered in an era of discovery and characterization of enzymes from novel organisms that fueled engineering of microbes to produce…”
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A microbial supply chain for production of the anti-cancer drug vinblastine by Zhang, Jie, Hansen, Lea G., Gudich, Olga, Viehrig, Konrad, Lassen, Lærke M. M., Schrübbers, Lars, Adhikari, Khem B., Rubaszka, Paulina, Carrasquer-Alvarez, Elena, Chen, Ling, D’Ambrosio, Vasil, Lehka, Beata, Haidar, Ahmad K., Nallapareddy, Saranya, Giannakou, Konstantina, Laloux, Marcos, Arsovska, Dushica, Jørgensen, Marcus A. K., Chan, Leanne Jade G., Kristensen, Mette, Christensen, Hanne B., Sudarsan, Suresh, Stander, Emily A., Baidoo, Edward, Petzold, Christopher J., Wulff, Tune, O’Connor, Sarah E., Courdavault, Vincent, Jensen, Michael K., Keasling, Jay D.

“…Monoterpene indole alkaloids (MIAs) are a diverse family of complex plant secondary metabolites with many medicinal properties, including the essential…”
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Viscous control of cellular respiration by membrane lipid composition by Budin, Itay, de Rond, Tristan, Chen, Yan, Chan, Leanne Jade G, Petzold, Christopher J, Keasling, Jay D

“…Lipid composition determines the physical properties of biological membranes and can vary substantially between and within organisms. We describe a specific…”
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Complete biosynthesis of cannabinoids and their unnatural analogues in yeast by Luo, Xiaozhou, Reiter, Michael A., d’Espaux, Leo, Wong, Jeff, Denby, Charles M., Lechner, Anna, Zhang, Yunfeng, Grzybowski, Adrian T., Harth, Simon, Lin, Weiyin, Lee, Hyunsu, Yu, Changhua, Shin, John, Deng, Kai, Benites, Veronica T., Wang, George, Baidoo, Edward E. K., Chen, Yan, Dev, Ishaan, Petzold, Christopher J., Keasling, Jay D.

“…Cannabis sativa L. has been cultivated and used around the globe for its medicinal properties for millennia 1 . Some cannabinoids, the hallmark constituents of…”
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Transgenic expression of the dicotyledonous pattern recognition receptor EFR in rice leads to ligand-dependent activation of defense responses by Schwessinger, Benjamin, Bahar, Ofir, Thomas, Nicholas, Thomas, Nicolas, Holton, Nicolas, Nekrasov, Vladimir, Ruan, Deling, Canlas, Patrick E, Daudi, Arsalan, Petzold, Christopher J, Singan, Vasanth R, Kuo, Rita, Chovatia, Mansi, Daum, Christopher, Heazlewood, Joshua L, Zipfel, Cyril, Ronald, Pamela C

“…Plant plasma membrane localized pattern recognition receptors (PRRs) detect extracellular pathogen-associated molecules. PRRs such as Arabidopsis EFR and rice…”
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Metabolic engineering of Saccharomyces cerevisiae for the production of n-butanol by Steen, Eric J, Chan, Rossana, Prasad, Nilu, Myers, Samuel, Petzold, Christopher J, Redding, Alyssa, Ouellet, Mario, Keasling, Jay D

“…Increasing energy costs and environmental concerns have motivated engineering microbes for the production of "second generation" biofuels that have better…”
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Synthetic protein scaffolds provide modular control over metabolic flux by Dueber, John E, Wu, Gabriel C, Malmirchegini, G Reza, Moon, Tae Seok, Petzold, Christopher J, Ullal, Adeeti V, Prather, Kristala L J, Keasling, Jay D

“…Engineered metabolic pathways are usually devoid of the regulatory mechanisms characteristic of natural metabolism. Using pathways not normally found in E…”
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Industrial brewing yeast engineered for the production of primary flavor determinants in hopped beer by Denby, Charles M., Li, Rachel A., Vu, Van T., Costello, Zak, Lin, Weiyin, Chan, Leanne Jade G., Williams, Joseph, Donaldson, Bryan, Bamforth, Charles W., Petzold, Christopher J., Scheller, Henrik V., Martin, Hector Garcia, Keasling, Jay D.

“…Flowers of the hop plant provide both bitterness and “hoppy” flavor to beer. Hops are, however, both a water and energy intensive crop and vary considerably in…”
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Machine learning for metabolic engineering: A review by Lawson, Christopher E., Martí, Jose Manuel, Radivojevic, Tijana, Jonnalagadda, Sai Vamshi R., Gentz, Reinhard, Hillson, Nathan J., Peisert, Sean, Kim, Joonhoon, Simmons, Blake A., Petzold, Christopher J., Singer, Steven W., Mukhopadhyay, Aindrila, Tanjore, Deepti, Dunn, Joshua G., Garcia Martin, Hector

“…Machine learning provides researchers a unique opportunity to make metabolic engineering more predictable. In this review, we offer an introduction to this…”
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Local and global structural drivers for the photoactivation of the orange carotenoid protein by Gupta, Sayan, Guttman, Miklos, Leverenz, Ryan L., Zhumadilova, Kulyash, Pawlowski, Emily G., Petzold, Christopher J., Lee, Kelly K., Ralston, Corie Y., Kerfeld, Cheryl A.

“…Photoprotective mechanisms are of fundamental importance for the survival of photosynthetic organisms. In cyanobacteria, the orange carotenoid protein (OCP),…”
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Engineering dynamic pathway regulation using stress-response promoters by Dahl, Robert H, Zhang, Fuzhong, Alonso-Gutierrez, Jorge, Baidoo, Edward, Batth, Tanveer S, Redding-Johanson, Alyssa M, Petzold, Christopher J, Mukhopadhyay, Aindrila, Lee, Taek Soon, Adams, Paul D, Keasling, Jay D

“…The problem of toxic intermediates in engineered metabolic pathways is mitigated by dynamic gene-expression regulation using stress-responsive promoters…”
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Genome-scale metabolic rewiring improves titers rates and yields of the non-native product indigoidine at scale by Banerjee, Deepanwita, Eng, Thomas, Lau, Andrew K., Sasaki, Yusuke, Wang, Brenda, Chen, Yan, Prahl, Jan-Philip, Singan, Vasanth R., Herbert, Robin A., Liu, Yuzhong, Tanjore, Deepti, Petzold, Christopher J., Keasling, Jay D., Mukhopadhyay, Aindrila

“…High titer, rate, yield (TRY), and scalability are challenging metrics to achieve due to trade-offs between carbon use for growth and production. To achieve…”
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Alkaline-SDS cell lysis of microbes with acetone protein precipitation for proteomic sample preparation in 96-well plate format by Chen, Yan, Gin, Jennifer W, Wang, Ying, de Raad, Markus, Tan, Stephen, Hillson, Nathan J, Northen, Trent R, Adams, Paul D, Petzold, Christopher J

“…Plate-based proteomic sample preparation offers a solution to the large sample throughput demands in the biotechnology field where hundreds or thousands of…”
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Biosynthesis and secretion of the microbial sulfated peptide RaxX and binding to the rice XA21 immune receptor by Luu, Dee Dee, Joe, Anna, Chen, Yan, Parys, Katarzyna, Bahar, Ofir, Pruitt, Rory, Chan, Leanne Jade G., Petzold, Christopher J., Long, Kelsey, Adamchak, Clifford, Stewart, Valley, Belkhadir, Youssef, Ronald, Pamela C.

“…The rice immune receptor XA21 is activated by the sulfated microbial peptide required for activation of XA21-mediated immunity X (RaxX) produced by Xanthomonas…”
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A miniaturized feedstocks-to-fuels pipeline for screening the efficiency of deconstruction and microbial conversion of lignocellulosic biomass by Pidatala, Venkataramana R, Lei, Mengziang, Choudhary, Hemant, Petzold, Christopher J, Garcia Martin, Hector, Simmons, Blake A, Gladden, John M, Rodriguez, Alberto

“…Sustainably grown biomass is a promising alternative to produce fuels and chemicals and reduce the dependency on fossil energy sources. However, the efficient…”
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Enhancing fatty acid production by the expression of the regulatory transcription factor FadR by Zhang, Fuzhong, Ouellet, Mario, Batth, Tanveer S., Adams, Paul D., Petzold, Christopher J., Mukhopadhyay, Aindrila, Keasling, Jay D.

“…Fatty acids are important precursors to biofuels. The Escherichia coli FadR is a transcription factor that regulates several processes in fatty acid…”
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Integrated analysis of isopentenyl pyrophosphate (IPP) toxicity in isoprenoid-producing Escherichia coli by George, Kevin W., Thompson, Mitchell G., Kim, Joonhoon, Baidoo, Edward E.K., Wang, George, Benites, Veronica Teixeira, Petzold, Christopher J., Chan, Leanne Jade G., Yilmaz, Suzan, Turhanen, Petri, Adams, Paul D., Keasling, Jay D., Lee, Taek Soon

“…Isopentenyl pyrophosphate (IPP) toxicity presents a challenge in engineered microbial systems since its formation is unavoidable in terpene biosynthesis. In…”
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Functional genetics of human gut commensal Bacteroides thetaiotaomicron reveals metabolic requirements for growth across environments by Liu, Hualan, Shiver, Anthony L., Price, Morgan N., Carlson, Hans K., Trotter, Valentine V., Chen, Yan, Escalante, Veronica, Ray, Jayashree, Hern, Kelsey E., Petzold, Christopher J., Turnbaugh, Peter J., Huang, Kerwyn Casey, Arkin, Adam P., Deutschbauer, Adam M.

“…Harnessing the microbiota for beneficial outcomes is limited by our poor understanding of the constituent bacteria, as the functions of most of their genes are…”
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A 12 Å carotenoid translocation in a photoswitch associated with cyanobacterial photoprotection by Leverenz, Ryan L., Sutter, Markus, Wilson, Adjélé, Gupta, Sayan, Thurotte, Adrien, de Carbon, Céline Bourcier, Petzold, Christopher J., Ralston, Corie, Perreau, François, Kirilovsky, Diana, Kerfeld, Cheryl A.

“…Pigment-protein and pigment-pigment interactions are of fundamental importance to the light-harvesting and photoprotective functions essential to oxygenic…”
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