Search Results - "Petzold, C."
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1
Role of Astrocytes in Neurovascular Coupling
Published in Neuron (Cambridge, Mass.) (08-09-2011)“…Neural activity is intimately tied to blood flow in the brain. This coupling is specific enough in space and time that modern imaging methods use local…”
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2
Inhibition of Stat3‐mediated astrogliosis ameliorates pathology in an Alzheimer's disease model
Published in EMBO molecular medicine (01-02-2019)“…Reactive astrogliosis is a hallmark of Alzheimer's disease (AD), but its role for disease initiation and progression has remained incompletely understood. We…”
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3
TRPV4 channels contribute to calcium transients in astrocytes and neurons during peri‐infarct depolarizations in a stroke model
Published in Glia (01-09-2017)“…Stroke is one of the leading causes of death and long‐term disability. In the penumbra, that is, the area surrounding the infarct core, peri‐infarct…”
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4
Antibody-mediated procoagulant platelets in SARS-CoV-2- vaccination associated immune thrombotic thrombocytopenia
Published in Haematologica (Roma) (20-05-2021)“…The COVID-19 pandemic has resulted in significant morbidity and mortality worldwide. To prevent severe infection, mass COVID-19 vaccination campaigns with…”
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5
Mechanical recanalization in basilar artery occlusion: The ENDOSTROKE study
Published in Annals of neurology (01-03-2015)“…Objective A study was undertaken to evaluate clinical and procedural factors associated with outcome and recanalization in endovascular stroke treatment (EVT)…”
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6
P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer's disease model
Published in The Journal of experimental medicine (04-06-2018)“…Astrocytic hyperactivity is an important contributor to neuronal-glial network dysfunction in Alzheimer's disease (AD). We have previously shown that astrocyte…”
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Astroglial NF-kB contributes to white matter damage and cognitive impairment in a mouse model of vascular dementia
Published in Acta neuropathologica communications (04-08-2016)“…Vascular cognitive impairment is the second most common form of dementia. The pathogenic pathways leading to vascular cognitive impairment remain unclear but…”
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8
Serotonergic modulation of odor input to the mammalian olfactory bulb
Published in Nature neuroscience (01-06-2009)“…Petzold and colleagues show that serotonergic innervation of the olfactory bulb functions to attenuate odor-evoked transmitter release from olfactory sensory…”
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9
Sodium Fluctuations in Astroglia and Their Potential Impact on Astrocyte Function
Published in Frontiers in physiology (12-08-2020)“…Astrocytes are the main cell type responsible for the regulation of brain homeostasis, including the maintenance of ion gradients and neurotransmitter…”
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10
Local Resting Ca2+ Controls the Scale of Astroglial Ca2+ Signals
Published in Cell reports (Cambridge) (10-03-2020)“…Astroglia regulate neurovascular coupling while engaging in signal exchange with neurons. The underlying cellular machinery is thought to rely on astrocytic…”
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11
Vagus nerve stimulation reduces spreading depolarization burden and cortical infarct volume in a rat model of stroke
Published in PloS one (23-07-2020)“…Cortical spreading depolarization (SD) waves negatively affect neuronal survival and outcome after ischemic stroke. We here aimed to investigate the effects of…”
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Coupling of Neural Activity to Blood Flow in Olfactory Glomeruli Is Mediated by Astrocytic Pathways
Published in Neuron (Cambridge, Mass.) (26-06-2008)“…Functional neuroimaging uses activity-dependent changes in cerebral blood flow to map brain activity, but the contributions of presynaptic and postsynaptic…”
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13
Apixaban for treatment of embolic stroke of undetermined source (ATTICUS randomized trial): Rationale and study design
Published in International Journal of Stroke (01-12-2017)“…Rationale Optimal secondary prevention of embolic stroke of undetermined source is not established. The current standard in these patients is acetylsalicylic…”
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14
Disruption of Glutamate Transport and Homeostasis by Acute Metabolic Stress
Published in Frontiers in cellular neuroscience (02-02-2021)“…High-affinity, Na -dependent glutamate transporters are the primary means by which synaptically released glutamate is removed from the extracellular space…”
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15
Neuroinflammation in Alzheimer's disease
Published in Lancet neurology (01-04-2015)“…Summary Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the neuronal compartment, but includes strong interactions with…”
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16
A role of the sodium pump in spreading ischemia in rats
Published in Journal of cerebral blood flow and metabolism (01-05-2017)“…In rats, spreading depolarization induces vasodilation/hyperemia in naïve tissue but the inverse response when artificial cerebrospinal fluid is topically…”
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17
Tissue mechanics govern the rapidly adapting and symmetrical response to touch
Published in Proceedings of the National Academy of Sciences - PNAS (15-12-2015)“…Interactions with the physical world are deeply rooted in our sense of touch and depend on ensembles of somatosensory neurons that invade and innervate the…”
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Slc1a3-2A-CreERT2 mice reveal unique features of Bergmann glia and augment a growing collection of Cre drivers and effectors in the 129S4 genetic background
Published in Scientific reports (08-03-2021)“…Genetic variation is a primary determinant of phenotypic diversity. In laboratory mice, genetic variation can be a serious experimental confounder, and thus…”
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19
Microsystems for biomimetic stimulation of cardiac cells
Published in Lab on a chip (21-09-2012)“…The heart is a complex integrated system that leverages mechanoelectrical signals to synchronize cardiomyocyte contraction and push blood throughout the body…”
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Changes of the retinal and choroidal vasculature in cerebral small vessel disease
Published in Scientific reports (07-03-2022)“…Cerebral small vessel disease (CSVD) is associated with changes in the retinal vasculature which can be assessed non-invasively with much higher resolution…”
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