Search Results - "Petzer, A."

Improvement in colorectal cancer outcomes over time is limited to patients with left-sided disease by Rumpold, Holger, Hackl, M., Petzer, A., Wolf, D.

“…Purpose Incidence and mortality of colorectal cancer (CRC) declined over the last decades. However, survival depends on the primary tumor location. It is…”
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Synthesis and Monoamine Oxidase Inhibition Properties of (Sulfamoylphenyl)quinoline-4-carboxylic Acids by Efimova, J., Shetnev, A., Korsakov, M., Petersen, E., Petzer, A., Petzer, J. P.

“…By reaction between acetylbenzenesulfonamides with several substituted isatins, we have synthesized a series of 22 primary sulfonamides, 16 of which were…”
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Epirubicin and docetaxel with or without capecitabine as neoadjuvant treatment for early breast cancer: final results of a randomized phase III study (ABCSG-24) by Steger, G.G., Greil, R., Lang, A., Rudas, M., Fitzal, F., Mlineritsch, B., Hartmann, B.L., Bartsch, R., Melbinger, E., Hubalek, M., Stoeger, H., Dubsky, P., Ressler, S., Petzer, A.L., Singer, C.F., Muss, C., Jakesz, R., Gampenrieder, S.P., Zielinski, C.C., Fesl, C., Gnant, M.

“…This randomized phase III trial compared pathologic complete response (pCR) rates of early breast cancer (EBC) following neoadjuvant epirubicin–docetaxel (ED)…”
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Adverse impact of a high CD4/CD8 ratio in the allograft may be overcome by methotrexate‐ but not mycophenolate‐ or post‐transplant cyclophosphamide‐based graft versus host disease prophylaxis by Nikoloudis, A., Buxhofer‐Ausch, V., Aichinger, C., Binder, M., Hasengruber, P., Kaynak, E., Wipplinger, D., Milanov, R., Strassl, I., Stiefel, O., Machherndl‐Spandl, S., Petzer, A., Weltermann, A., Clausen, J.

“…Introduction A high CD4/CD8 T cell ratio in hematopoietic stem cell transplant (HSCT) allografts was observed to predict graft‐versus‐host disease (GVHD) and…”
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The inhibition of monoamine oxidase by esomeprazole by Petzer, A, Pienaar, A, Petzer, J P

“…Virtual screening of a library of drugs has suggested that esomeprazole, the S-enantiomer of omeprazole, may possess binding affinities for the active sites of…”
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Different subsets of primary chronic myeloid leukemia stem cells engraft immunodeficient mice and produce a model of the human disease by EISTERER, W, JIANG, X, AUEWARAKUL, C, BARNETT, M. J, EAVES, C. J, EAVES, A. C, CHRIST, O, GLIMM, H, LEE, K. H, PANG, E, LAMBIE, K, SHAW, G, HOLYOAKE, T. L, PETZER, A. L

“…Xenograft models of chronic phase human chronic myeloid leukemia (CML) have been difficult to develop because of the persistence of normal hematopoietic stem…”
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Impact of natural killer cell dose and donor killer-cell immunoglobulin-like receptor (KIR) genotype on outcome following human leucocyte antigen-identical haematopoietic stem cell transplantation by Clausen, J, Wolf, D, Petzer, A.L, Gunsilius, E, Schumacher, P, Kircher, B, Gastl, G, Nachbaur, D

“…To define the role of quantitative graft composition and donor killer-cell immunoglobulin-like receptor (KIR) genotype in clinical outcome following…”
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Synthesis and Antimonoamine Oxidase Activity of 2-(3-Iminoisoindol-1-ylidene)-2-arylacetonitriles by Grigor’eva, A. I., Shetnev, A. A., Kotov, A. D., Ivanovskii, S. A., Petzer, A., Petzer, J. P.

“…A one-pot synthesis of 2-(3-iminoisoindol-1-ylidene)-2-arylacetonitriles in yields of up to 95% by the cascade condensation of phthalonitrile with…”
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Expansion in vitro of Transplantable Human Cord Blood Stem Cells Demonstrated Using a Quantitative Assay of their Lympho-Myeloid Repopulating Activity in Nonobese Diabetic-Scid/Scid Mice by Conneally, E., Cashman, J., Petzer, A., Eaves, C.

“…Human hematopoiesis originates in a population of stem cells with transplantable lympho-myeloid reconstituting potential, but a method for quantitating such…”
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Prospective observational study to evaluate the persistence of treatment with denosumab (dmab) in patients (pts) with bone metastases (BM) from solid tumors (ST) in routine clinical practice: Final analysis by Haslbauer, F., Petzer, A.L., Safanda, M., Tomova, A., Porubska, M., Bajory, Z., Niepel, D., Jäger, C., Kalinin, D., Greil, R.

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The AST/ALT (De Ritis) ratio predicts clinical outcome in pancreatic cancer patients treated with first-line nab-paclitaxel and gemcitabine: post-hoc analysis of an Austrian multicenter, non-interventional study by Riedl, J., Posch, F., Prager, G., Eisterer, W., Öhler, L., Thamer, S., Wilthoner, K., Petzer, A., Pichler, P., Hubmann, E., Winder, T., Burgstaller, S., Korger, M., Andel, J., Greil, R., Pecherstorfer, M., Philipp-Abbrederis, K., Djanani, A., Gruenberger, B., Längle, F., Wöll, E., Gerger, A.

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Development and validation of a HPLC electrochemical detection method to measure COMT activity as a tool in drug development by Viljoen, F P, Preez, J L Du, Petzer, A, Wessels, J C, Petzer, J, Aucamp, M E

“…The determination of catechol-O-methyltransferase (COMT) activity is considered valuable for various pharmaceutical and biomedical research projects. A…”
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Bevacizumab mitigates codon specific effects of trifluridine/tipiracil on efficacy outcome parameters in metastatic colorectal cancer by Doleschal, Bernhard, Taghizadeh, Hossein, Lentner, Theresa, Riedl, Jakob M., Granitzer, Janine, Morariu, Darius, Decker, Jörn, Aichberger, Karl J., Webersinke, Gerald, Kirchweger, Patrick, Petzer, Andreas, Rumpold, Holger

“…Molecular informed therapy changed treatment patterns of metastatic colorectal cancer. Recently KRAS G12, the most prevalent RAS mutation in mCRC, was…”
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Austrian real world data in elderly and younger metastatic pancreatic cancer patients: Interim results of a multicenter non-interventional study with nab-paclitaxel/gemcitabine by Eisterer, W., Gerger, A., Öhler, L., Mlineritsch, B., Sliwa, T., Wilthoner, K., Petzer, A., Pichler, P., Hubmann, E., Winder, T., Burgstaller, S., Korger, M., Andel, J., Wöll, E., Neumann, H., Pecherstorfer, M., Philipp-Abbrederis, K., Djanani, A., Gruenberger, B., Längle, F., Prager, G.

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The inhibition of monoamine oxidase by phenformin and pentamidine by Barkhuizen, M, Petzer, A, Petzer, J P

“…A computational study has suggested that phenformin, an oral hypoglycaemic drug, may bind to the active sites of the monoamine oxidase (MAO) A and B enzymes…”
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Evidence from a leukaemia model for maintenance of vascular endothelium by bone-marrow-derived endothelial cells by Gunsilius, Eberhard, Duba, Hans-Christoph, Petzer, Andreas L, Kahler, Christian M, Grunewald, Kurt, Stockhammer, Gunther, Gabl, Christoph, Dirnhofer, Stephan, Clausen, Johannes, Gastl, Gunther

“…Vascular endothelial cells lost from the bloodvessel endothelium through necrosis or apoptosis must be replaced. We investigated in a leukaemia model whether…”
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The inhibition of acetylcholinesterase by dantrolene and ondansetron by N'Da, C I, Petzer, A, Petzer, J P

“…A virtual screening study has suggested that the skeletal muscle relaxant, dantrolene, and the antiemetic drug, ondansetron, may act as inhibitors of the…”
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PATIENT‐REPORTED QUALITY OF LIFE (QOL) FOLLOWING TISAGENLECLEUCEL (TISA‐CEL) INFUSION IN ADULT PATIENTS (PTS) WITH RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA (R/R FL) by Fowler, N. H., Dickinson, M., Martinez‐Lopez, J., Kolstad, A., Schuster, S. J., Dreyling, M., Ghosh, M., Harigae, H., Kersten, M. José, Bachy, E., Popplewell, L., Chavez, J. C., Ho, P. J., Butler, J., Kato, K., von Tresckow, B., Ferreri, A. J. M., Simón, J. A. P., Patten, P. E. M., Andreadis, C., Riedell, P. A., McGuirk, J. P., Nastoupil, L. J., Teshima, T., Offner, F., Petzer, A., Viardot, A., Zinzani, P. L., Malladi, R., Zhang, J., Tiwari, R., Bollu, V., Masood, A., Thieblemont, C.

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Cytokine Manipulation of Primitive Human Hematopoietic Cell Self-Renewal by Zandstra, P. W., Conneally, E., Petzer, A. L., Piret, J. M., Eaves, C. J.

“…Previous studies have shown that primitive human hematopoietic cells detectable as long-term culture-initiating cells (LTC-ICs) and colony-forming cells (CFCs)…”
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S179: RANDOMIZED COMPARISON BETWEEN KRD AND KTD INDUCTION, FOLLOWED BY K MAINTENANCE OR OBSERVATION IN TRANSPLANT NON‐ELIGIBLE PATIENTS WITH NDMM (AGMT‐MM02 TRIAL) by Ludwig, H., Melchardt, T., Sormann, S., Zojer, N., Andel, J., Hartmann, B., Tinchon, C., Gunsilius, E., Podar, K., Egle, A., Willenbacher, W., Wöll, E., Schreder, M., Ruckser, R., Bozic, B, Krauth, M.‐T., Petzer, A., Schmitt, C, Machherndl‐Spandl, S., Agis, H., Fillitz, M., Pönisch, W., Knop, S., Paiva, B., Greil, R.

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