Search Results - "Petur Nielsen, G"

Beyond “Triton”: Malignant Peripheral Nerve Sheath Tumors With Complete Heterologous Rhabdomyoblastic Differentiation Mimicking Spindle Cell Rhabdomyosarcoma by Hornick, Jason L, Nielsen, G Petur

“…Spindle cell rhabdomyosarcoma (RMS) is an aggressive sarcoma type with a predilection for the head and neck and frequent transactivating MYOD1 mutations…”
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Differential Diagnosis of Cartilaginous Lesions of Bone by Suster, David, Hung, Yin Pun, Nielsen, G Petur

“…Cartilaginous tumors represent one of the most common tumors of bone. Management of these tumors includes observation, curettage, and surgical excision or…”
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EWSR1/FUS–CREB fusions define a distinctive malignant epithelioid neoplasm with predilection for mesothelial-lined cavities by Argani, Pedram, Harvey, Isabel, Nielsen, G. Petur, Takano, Angela, Suurmeijer, Albert J.H., Voltaggio, Lysandra, Zhang, Lei, Sung, Yun-Shao, Stenzinger, Albrecht, Mechtersheimer, Gunhild, Dickson, Brendan C., Antonescu, Cristina R.

“…Gene fusions constitute pivotal driver mutations often encoding aberrant chimeric transcription factors. However, an increasing number of gene fusion events…”
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EWSR1-POU5F1 fusion in soft tissue myoepithelial tumors. A molecular analysis of sixty-six cases, including soft tissue, bone, and visceral lesions, showing common involvement of the EWSR1 gene by Antonescu, Cristina R., Zhang, Lei, Chang, Ning-En, Pawel, Bruce R., Travis, William, Katabi, Nora, Edelman, Morris, Rosenberg, Andrew E., Petur Nielsen, G., Cin, Paola Dal, Fletcher, Christopher D.M.

“…The diagnosis of myoepithelial (ME) tumors outside salivary glands remains challenging, especially in unusual clinical presentations, such as bone or visceral…”
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Bone Marrow and Peripheral Blood Findings in Patients Infected by SARS-CoV-2 by Harris, Cynthia K, Hung, Yin P, Nielsen, G Petur, Stone, James R, Ferry, Judith A

“…Abstract Objectives Coronavirus disease 19 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is associated with diverse…”
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Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma by Hayes, Madeline N., McCarthy, Karin, Jin, Alexander, Oliveira, Mariana L., Iyer, Sowmya, Garcia, Sara P., Sindiri, Sivasish, Gryder, Berkley, Motala, Zainab, Nielsen, G. Petur, Borg, Jean-Paul, van de Rijn, Matt, Malkin, David, Khan, Javed, Ignatius, Myron S., Langenau, David M.

“…Tumor growth and relapse are driven by tumor propagating cells (TPCs). However, mechanisms regulating TPC fate choices, maintenance, and self-renewal are not…”
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mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake by Yilmaz, Ömer H., Katajisto, Pekka, Lamming, Dudley W., Gültekin, Yetis, Bauer-Rowe, Khristian E., Sengupta, Shomit, Birsoy, Kivanc, Dursun, Abdulmetin, Yilmaz, V. Onur, Selig, Martin, Nielsen, G. Petur, Mino-Kenudson, Mari, Zukerberg, Lawrence R., Bhan, Atul K., Deshpande, Vikram, Sabatini, David M.

“…How adult tissue stem and niche cells respond to the nutritional state of an organism is not well understood. Here we find that Paneth cells, a key constituent…”
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EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma by Riggi, Nicolò, Knoechel, Birgit, Gillespie, Shawn M., Rheinbay, Esther, Boulay, Gaylor, Suvà, Mario L., Rossetti, Nikki E., Boonseng, Wannaporn E., Oksuz, Ozgur, Cook, Edward B., Formey, Aurélie, Patel, Anoop, Gymrek, Melissa, Thapar, Vishal, Deshpande, Vikram, Ting, David T., Hornicek, Francis J., Nielsen, G. Petur, Stamenkovic, Ivan, Aryee, Martin J., Bernstein, Bradley E., Rivera, Miguel N.

“…The aberrant transcription factor EWS-FLI1 drives Ewing sarcoma, but its molecular function is not completely understood. We find that EWS-FLI1 reprograms gene…”
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EWSR1/FUS-NFATc2 rearranged round cell sarcoma: clinicopathological series of 4 cases and literature review by Diaz-Perez, Julio A., Nielsen, G. Petur, Antonescu, Cristina, Taylor, Martin S., Lozano-Calderon, Santiago A., Rosenberg, Andrew E.

“…The classification of bone neoplasms composed of small round cells is experiencing a transformation after the discovery of various gene fusion rearrangements…”
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Riedel's Thyroiditis and Multifocal Fibrosclerosis are part of the IgG4‐related systemic disease spectrum by Dahlgren, Mollie, Khosroshahi, Arezou, Nielsen, G. Petur, Deshpande, Vikram, Stone, John H.

“…Objective Riedel's thyroiditis is a chronic fibrosing disorder of unknown etiology often associated with “multifocal fibrosclerosis.” IgG4‐related systemic…”
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Dedifferentiated Chordoma: Clinicopathologic and Molecular Characteristics With Integrative Analysis by Hung, Yin P., Diaz-Perez, Julio A., Cote, Gregory M., Wejde, Johan, Schwab, Joseph H., Nardi, Valentina, Chebib, Ivan A., Deshpande, Vikram, Selig, Martin K., Bredella, Miriam A., Rosenberg, Andrew E., Nielsen, G. Petur

“…Dedifferentiated chordoma is a rare chordoma subtype characterized by a high-grade sarcoma juxtaposed to conventional chordoma. We identified a series of…”
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Bone and soft tissue pathology by Folpe, Andrew L, Nielsen, G Petur

“…Now fully revised to include recent advances in the field, the second edition of Bone and Soft Tissue Pathology, a volume in the Foundations in Diagnostic…”
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Defective HLA Class I Expression and Patterns of Lymphocyte Infiltration in Chordoma Tumors by Patel, Shalin S., Nota, Sjoerd P., Sabbatino, Francesco, Nielsen, G. Petur, Deshpande, Vikram, Wang, Xinhui, Ferrone, Soldano, Schwab, Joseph H.

“…There are no effective systemic therapies for chordoma. The recent successes of immunotherapeutic strategies in other cancers have resulted in a resurgence of…”
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Long-term results of Phase II study of high dose photon/proton radiotherapy in the management of spine chordomas, chondrosarcomas, and other sarcomas by DeLaney, Thomas F., Liebsch, Norbert J., Pedlow, Frank X., Adams, Judith, Weyman, Elizabeth A., Yeap, Beow Y., Depauw, Nicolas, Nielsen, G. Petur, Harmon, David C., Yoon, Sam S., Chen, Yen-Lin, Schwab, Joseph H., Hornicek, Francis J.

“…Background Negative surgical margins are uncommon for spine sarcomas; hence, adjuvant radiotherapy (RT) may be recommended but tumor dose may be constrained by…”
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Characterization of FN1–FGFR1 and novel FN1–FGF1 fusion genes in a large series of phosphaturic mesenchymal tumors by Lee, Jen-Chieh, Su, Sheng-Yao, Changou, Chun A, Yang, Rong-Sen, Tsai, Keh-Sung, Collins, Michael T, Orwoll, Eric S, Lin, Chung-Yen, Chen, Shu-Hwa, Shih, Shyang-Rong, Lee, Cheng-Han, Oda, Yoshinao, Billings, Steven D, Li, Chien-Feng, Nielsen, G Petur, Konishi, Eiichi, Petersson, Fredrik, Carpenter, Thomas O, Sittampalam, Kesavan, Huang, Hsuan-Ying, Folpe, Andrew L

“…Phosphaturic mesenchymal tumors typically cause paraneoplastic osteomalacia, chiefly as a result of FGF23 secretion. In a prior study, we identified FN1–FGFR1…”
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Radiation-induced and neurofibromatosis-associated malignant peripheral nerve sheath tumors (MPNST) have worse outcomes than sporadic MPNST by Miao, Ruoyu, Wang, Haotong, Jacobson, Alex, Lietz, Anna P., Choy, Edwin, Raskin, Kevin A., Schwab, Joseph H., Deshpande, Vikram, Nielsen, G. Petur, DeLaney, Thomas F., Cote, Gregory M., Hornicek, Francis J., Chen, Yen-Lin E.

“…•Both radiation-induced and neurofibromatosis-associated MPNSTs have poorer prognosis than sporadic MPNSTs.•Complete resection of the tumor is a significant…”
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ASO Visual Abstract: Assessing the Safety and Utility of Wound VAC Temporization of the Sarcoma or Benign Aggressive Tumor Bed Until Final Margins are Achieved by Fourman, Mitchell S., Ramsey, Duncan C., Newman, Erik T., Schwab, Joseph H., Chen, Yen-Lin, Hung, Yin P., Chebib, Ivan, Deshpande, Vikram, Petur Nielsen, G., DeLaney, Thomas F., Mullen, John T., Raskin, Kevin A., Lozano-Calderon, Santiago

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Desmoid Tumor: Analysis of Prognostic Factors and Outcomes in a Surgical Series by Mullen, John T., DeLaney, Thomas F., Kobayashi, Wendy K., Szymonifka, Jackie, Yeap, Beow Y., Chen, Yen-Lin, Rosenberg, Andrew E., Harmon, David C., Choy, Edwin, Yoon, Sam S., Raskin, Kevin A., Petur Nielsen, G., Hornicek, Francis J.

“…Background Desmoid tumors are rare and exhibit a highly unpredictable natural history. We sought to analyze prognostic factors associated with recurrence in a…”
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Immunohistochemistry for histone H3G34W and H3K36M is highly specific for giant cell tumor of bone and chondroblastoma, respectively, in FNA and core needle biopsy by Schaefer, Inga‐Marie, Fletcher, Jonathan A., Nielsen, G. Petur, Shih, Angela R., Ferrone, Marco L., Hornick, Jason L., Qian, Xiaohua

“…BACKGROUND Diagnosing giant cell‐rich bone tumors can be challenging on limited biopsies. H3 histone family member 3A (H3F3A) (G34W/V/R/L) mutations are…”
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EWSR1-ATF1 dependent 3D connectivity regulates oncogenic and differentiation programs in Clear Cell Sarcoma by Möller, Emely, Praz, Viviane, Rajendran, Sanalkumar, Dong, Rui, Cauderay, Alexandra, Xing, Yu-Hang, Lee, Lukuo, Fusco, Carlo, Broye, Liliane C., Cironi, Luisa, Iyer, Sowmya, Rengarajan, Shruthi, Awad, Mary E., Naigles, Beverly, Letovanec, Igor, Ormas, Nicola, Finzi, Giovanna, La Rosa, Stefano, Sessa, Fausto, Chebib, Ivan, Petur Nielsen, G., Digklia, Antonia, Spentzos, Dimitrios, Cote, Gregory M., Choy, Edwin, Aryee, Martin, Stamenkovic, Ivan, Boulay, Gaylor, Rivera, Miguel N., Riggi, Nicolò

“…Oncogenic fusion proteins generated by chromosomal translocations play major roles in cancer. Among them, fusions between EWSR1 and transcription factors…”
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