Search Results - "Pettway, Glenda J"

Cyclin D1 as a Target for the Proliferative Effects of PTH and PTHrP in Early Osteoblastic Cells by Datta, Nabanita S, Pettway, Glenda J, Chen, Chen, Koh, Amy J, McCauley, Laurie K

“…PTHrP induced a proliferative cyclin D1 activation in low‐density osteoblastic cells. The process was PKA and MAPK dependent and involved both AP‐1 and CRE…”
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Parathyroid hormone mediates bone growth through the regulation of osteoblast proliferation and differentiation by Pettway, Glenda J, Meganck, Jeffrey A, Koh, Amy J, Keller, Evan T, Goldstein, Steven A, McCauley, Laurie K

“…Abstract PTH (1–34) is the only FDA-approved anabolic agent for osteoporosis treatment in the U.S., but its mechanisms are not completely understood. This…”
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The release profiles and bioactivity of parathyroid hormone from poly(lactic-co-glycolic acid) microspheres by Wei, Guobao, Pettway, Glenda J., McCauley, Laurie K., Ma, Peter X.

“…Poly(lactic-co-glycolic acid) (PLGA) microspheres containing bovine serum albumin (BSA) or human parathyroid hormone (PTH)(1–34) were prepared using a double…”
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Pulsatile release of parathyroid hormone from an implantable delivery system by Liu, Xiaohua, Pettway, Glenda J, McCauley, Laurie K, Ma, Peter X

“…Abstract Intermittent (pulsatile) administration of parathyroid hormone (PTH) is known to improve bone micro-architecture, mineral density and strength…”
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JunB as a Downstream Mediator of PTHrP Actions in Cementoblasts by Berry, Janice E, Ealba, Erin L, Pettway, Glenda J, Datta, Nabanita S, Swanson, Erica C, Somerman, Martha J, McCauley, Laurie K

“…The role of AP‐1 family members in the action of PTHrP was examined in cementoblasts. PTHrP increased mRNA and protein levels of all Fos members, but only one…”
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Proteoglycan 4: A dynamic regulator of skeletogenesis and parathyroid hormone skeletal anabolism by Novince, Chad M, Michalski, Megan N, Koh, Amy J, Sinder, Benjamin P, Entezami, Payam, Eber, Matthew R, Pettway, Glenda J, Rosol, Thomas J, Wronski, Thomas J, Kozloff, Ken M, McCauley, Laurie K

“…Proteoglycan 4 (Prg4), known for its lubricating and protective actions in joints, is a strong candidate regulator of skeletal homeostasis and parathyroid…”
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Ossicle and vossicle implant model systems by Pettway, Glenda J, McCauley, Laurie K

“…Bone regeneration and repair is a goal of many skeletal therapies and numerous agents positively or negatively impact these processes. New therapeutic agents…”
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Anabolic actions of PTH (1-34): Use of a novel tissue engineering model to investigate temporal effects on bone by Pettway, Glenda J., Schneider, Abraham, Koh, Amy J., Widjaja, Effendi, Morris, Michael D., Meganck, Jeffrey A., Goldstein, Steven A., McCauley, Laurie K.

“…PTH is in clinical use for the treatment of osteoporosis and is under intensive investigation for its potential in applications of tissue engineering, fracture…”
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Cell Surface Expression of Stem Cell Antigen-1 (Sca-1) Distinguishes Osteo-, Chondro-, and Adipoprogenitors in Fetal Mouse Calvaria by Steenhuis, Pieter, Pettway, Glenda J., Ignelzi, Michael A.

“…The flat bones of the skull (calvaria) develop by balanced cell proliferation and differentiation in the calvarial sutures and the bone tips. As the brain…”
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Regulation of mitogen-activated protein kinase phosphatase-1 by PTH/PTHrP involves cAMP and PKC pathways in differentiated osteoblasts by Kolailat, Rola, Pettway, Glenda J, McCauley, Laurie K, Abou-Samra, Abdul B, Datta, Nabanita S

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JunB as a potential mediator of PTHrP actions: new gene targets Ephrin B1 and VCAM‐1 by Berry, JE, Pettway, GJ, Cordell, KG, Jin, T, Datta, NS, McCauley, LK

“…Parathyroid hormone‐related protein (PTHrP) is an integral mediator of physiologic and pathologic processes and has demonstrated actions in the periodontium…”
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Anabolic actions of PTH (1-34): Temporal and mechanistic impact on cell proliferation and differentiation during engineered bone regeneration by Pettway, Glenda J

“…The use of pharmacologic agents, such as parathyroid hormone (PTH), capable of promoting bone formation offers exciting new approaches to address the critical…”
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