Search Results - "Pettman, G."

N‐terminal or signal peptide sequence engineering prevents truncation of human monoclonal antibody light chains by Gibson, S. J., Bond, N. J., Milne, S., Lewis, A., Sheriff, A., Pettman, G., Pradhan, R., Higazi, D. R., Hatton, D.

“…ABSTRACT Monoclonal antibodies (mAbs) contain short N‐terminal signal peptides on each individual polypeptide that comprises the mature antibody, targeting…”
Get full text

Sema7A is a Potent Monocyte Stimulator by HOLMES, S., DOWNS, A.‐M., FOSBERRY, A., HAYES, P. D., MICHALOVICH, D., MURDOCH, P., MOORES, K., FOX, J., DEEN, K., PETTMAN, G., WATTAM, T., LEWIS, C.

“…Sema7A is a recently described member of the semaphorin family that is associated with the cell surface via a glycophosphatidylinositol linkage. This study…”
Get full text

Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor by Hirano, Kazufumi, Chen, Woei Shin, Chueng, Adeline L W, Dunne, Angela A, Seredenina, Tamara, Filippova, Aleksandra, Ramachandran, Sumitra, Bridges, Angela, Chaudry, Laiq, Pettman, Gary, Allan, Craig, Duncan, Sarah, Lee, Kiew Ching, Lim, Jean, Ma, May Thu, Ong, Agnes B, Ye, Nicole Y, Nasir, Shabina, Mulyanidewi, Sri, Aw, Chiu Cheong, Oon, Pamela P, Liao, Shihua, Li, Dizheng, Johns, Douglas G, Miller, Neil D, Davies, Ceri H, Browne, Edward R, Matsuoka, Yasuji, Chen, Deborah W, Jaquet, Vincent, Rutter, A Richard

“…The NADPH oxidase (NOX) family of enzymes catalyzes the formation of reactive oxygen species (ROS). NOX enzymes not only have a key role in a variety of…”
Get more information

Expression, Purification, and Functional Analysis of the Human Serine Protease HtrA2 by Savopoulos, John W., Carter, Paul S., Turconi, Sandra, Pettman, Gary R., Karran, Eric H., Gray, Carol W., Ward, Robin V., Jenkins, Owen, Creasy, Caretha L.

“…HumHtrA2 or Omi is a recently described member of a novel family of mammalian serine proteases homologous to the Escherichia coli htrA gene product. Although…”
Get full text

The Structure of Phosphorylated GSK-3β Complexed with a Peptide, FRATtide, that Inhibits β-Catenin Phosphorylation by Bax, Benjamin, Carter, Paul S., Lewis, Ceri, Guy, Angela R., Bridges, Angela, Tanner, Robert, Pettman, Gary, Mannix, Chris, Culbert, Ainsley A., Brown, Murray J.B., Smith, David G., Reith, Alastair D.

“…Background: Glycogen synthase kinase-3 (GSK-3) sequentially phosphorylates four serine residues on glycogen synthase (GS), in the sequence…”
Get full text

The Structure of MSK1 Reveals a Novel Autoinhibitory Conformation for a Dual Kinase Protein by Smith, Kathrine J, Carter, Paul S, Bridges, Angela, Horrocks, Pete, Lewis, Ceri, Pettman, Gary, Clarke, Andrew, Brown, Murray, Hughes, Jane, Wilkinson, Marc, Bax, Benjamin, Reith, Alastair

“…Mitogen and stress-activated kinase-1 (MSK1) is a serine/threonine protein kinase that is activated by either p38 or p42ERK MAPKs in response to stress or…”
Get full text

The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation by Bax, B, Carter, P S, Lewis, C, Guy, A R, Bridges, A, Tanner, R, Pettman, G, Mannix, C, Culbert, A A, Brown, M J, Smith, D G, Reith, A D

“…Glycogen synthase kinase-3 (GSK-3) sequentially phosphorylates four serine residues on glycogen synthase (GS), in the sequence SxxxSxxxSxxx-SxxxS(p), by…”
Get full text

Water intoxication due to oxytocin. Report of a case by PETTMAN, J G

Get more information