Search Results - "Petti, Eleonora"

SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability by Petti, Eleonora, Buemi, Valentina, Zappone, Antonina, Schillaci, Odessa, Broccia, Pamela Veneziano, Dinami, Roberto, Matteoni, Silvia, Benetti, Roberta, Schoeftner, Stefan

“…In vertebrates, the telomere repeat containing long, non-coding RNA TERRA is prone to form RNA:DNA hybrids at telomeres. This results in the formation of…”
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miR-155 Drives Telomere Fragility in Human Breast Cancer by Targeting TRF1 by DINAMI, Roberto, ERCOLANI, Cristiana, BENETTI, Roberta, MOTTOLESE, Marcella, SCHNEIDER, Claudio, BLANDINO, Giovanni, SCHOEFTNER, Stefan, PETTI, Eleonora, PIAZZA, Silvano, CIANI, Yari, SESTITO, Rosanna, SACCONI, Andrea, BIAGIONI, Francesca, LE SAGE, Carlos, AGAMI, Reuven

“…Telomeres consist of DNA tandem repeats that recruit the multiprotein complex shelterin to build a chromatin structure that protects chromosome ends. Although…”
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MiR‐182‐3p targets TRF2 and impairs tumor growth of triple‐negative breast cancer by Dinami, Roberto, Pompili, Luca, Petti, Eleonora, Porru, Manuela, D'Angelo, Carmen, Di Vito, Serena, Rizzo, Angela, Campani, Virginia, De Rosa, Giuseppe, Bruna, Alejandra, Serra, Violeta, Mano, Miguel, Giacca, Mauro, Leonetti, Carlo, Ciliberto, Gennaro, Tarsounas, Madalena, Stoppacciaro, Antonella, Schoeftner, Stefan, Biroccio, Annamaria

“…The telomeric repeat‐binding factor 2 (TRF2) is a telomere‐capping protein that plays a key role in the maintenance of telomere structure and function. It is…”
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Epigenetic silencing of miR-296 and miR-512 ensures hTERT dependent apoptosis protection and telomere maintenance in basal-type breast cancer cells by Dinami, Roberto, Buemi, Valentina, Sestito, Rosanna, Zappone, Antonina, Ciani, Yari, Mano, Miguel, Petti, Eleonora, Sacconi, Andrea, Blandino, Giovanni, Giacca, Mauro, Piazza, Silvano, Benetti, Roberta, Schoeftner, Stefan

“…The catalytic subunit of the telomerase complex, hTERT, ensures unlimited proliferative potential of cancer cells by maintaining telomere function and…”
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TRF2 as novel marker of tumor response to taxane-based therapy: from mechanistic insight to clinical implication by Iachettini, Sara, Terrenato, Irene, Porru, Manuela, Di Vito, Serena, Rizzo, Angela, D'Angelo, Carmen, Petti, Eleonora, Dinami, Roberto, Maresca, Carmen, Di Benedetto, Anna, Palange, Aldo, Mulè, Antonino, Santoro, Angela, Palazzo, Antonella, Fuso, Paola, Stoppacciaro, Antonella, Vici, Patrizia, Filomeno, Lorena, Di Lisa, Francesca Sofia, Arcuri, Teresa, Krasniqi, Eriseld, Fabi, Alessandra, Biroccio, Annamaria, Zizza, Pasquale

“…Breast Cancer (BC) can be classified, due to its heterogeneity, into multiple subtypes that differ for prognosis and clinical management. Notably, triple…”
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The telomeric protein TERF2/TRF2 impairs HMGB1-driven autophagy by Iachettini, Sara, Ciccarone, Fabio, Maresca, Carmen, D' Angelo, Carmen, Petti, Eleonora, Di Vito, Serena, Ciriolo, Maria Rosa, Zizza, Pasquale, Biroccio, Annamaria

“…TERF2/TRF2 is a pleiotropic telomeric protein that plays a crucial role in tumor formation and progression through several telomere-dependent and -independent…”
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TRF2 cooperates with CTCF for controlling the oncomiR-193b-3p in colorectal cancer by Dinami, Roberto, Petti, Eleonora, Porru, Manuela, Rizzo, Angela, Ganci, Federica, Sacconi, Andrea, Ostano, Paola, Chiorino, Giovanna, Trusolino, Livio, Blandino, Giovanni, Ciliberto, Gennaro, Zizza, Pasquale, Biroccio, Annamaria

“…The Telomeric Repeat binding Factor 2 (TRF2), a key protein involved in telomere integrity, is over-expressed in several human cancers and promotes tumor…”
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TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment by Zizza, Pasquale, Dinami, Roberto, Porru, Manuela, Cingolani, Chiara, Salvati, Erica, Rizzo, Angela, D’Angelo, Carmen, Petti, Eleonora, Amoreo, Carla Azzurra, Mottolese, Marcella, Sperduti, Isabella, Chambery, Angela, Russo, Rosita, Ostano, Paola, Chiorino, Giovanna, Blandino, Giovanni, Sacconi, Andrea, Cherfils-Vicini, Julien, Leonetti, Carlo, Gilson, Eric, Biroccio, Annamaria

“…Abstract The telomeric protein TRF2 is overexpressed in several human malignancies and contributes to tumorigenesis even though the molecular mechanism is not…”
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Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice by Petti, Eleonora, Jordi, Fabian, Buemi, Valentina, Dinami, Roberto, Benetti, Roberta, Blasco, Maria A, Schoeftner, Stefan

“…The Suv39h1 and Suv39h2 H3K9 histone methyltransferases (HMTs) have a conserved role in the formation of constitutive heterochromatin and gene silencing. Using…”
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Altered telomere homeostasis and resistance to skin carcinogenesis in Suv39h1 transgenic mice by Petti, Eleonora, Jordi, Fabian, Buemi, Valentina, Dinami, Roberto, Benetti, Roberta, Blasco, Maria A, Schoeftner, Stefan

“…The Suv39h1 and Suv39h2 H3K9 histone methyltransferases (HMTs) have a conserved role in the formation of constitutive heterochromatin and gene silencing. Using…”
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