Search Results - "Pettersson, Lina M. E"
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Embedded Ultrathin Cluster Electrodes for Long-Term Recordings in Deep Brain Centers
Published in PloS one (09-05-2016)“…Neural interfaces which allow long-term recordings in deep brain structures in awake freely moving animals have the potential of becoming highly valuable tools…”
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Injury-associated PACAP expression in rat sensory and motor neurons is induced by endogenous BDNF
Published in PloS one (26-06-2014)“…Peripheral nerve injury results in dramatic upregulation in pituitary adenylate cyclase activating polypeptide (PACAP) expression in adult rat dorsal root…”
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Multiple implants do not aggravate the tissue reaction in rat brain
Published in PloS one (16-10-2012)“…Chronically implanted microelectrodes are an invaluable tool for neuroscientific research, allowing long term recordings in awake and behaving animals. It is…”
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Size-dependent long-term tissue response to biostable nanowires in the brain
Published in Biomaterials (01-02-2015)“…Abstract Nanostructured neural interfaces, comprising nanotubes or nanowires, have the potential to overcome the present hurdles of achieving stable…”
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Endogenous BDNF regulates induction of intrinsic neuronal growth programs in injured sensory neurons
Published in Experimental neurology (01-05-2010)“…Identification of the molecule(s) that globally induce a robust regenerative state in sensory neurons following peripheral nerve injury remains elusive. A…”
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Nanowire Biocompatibility in the Brain - Looking for a Needle in a 3D Stack
Published in Nano letters (09-12-2009)“…We investigated the brain-tissue response to nanowire implantations in the rat striatum after 1, 6, and 12 weeks using immunohistochemistry. The nanowires…”
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Impact of degradable nanowires on long-term brain tissue responses
Published in Journal of nanobiotechnology (09-08-2016)“…A promising approach to improve the performance of neural implants consists of adding nanomaterials, such as nanowires, to the surface of the implant…”
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Microelectrode clusters enable therapeutic deep brain stimulation without noticeable side-effects in a rodent model of Parkinson’s disease
Published in Journal of neuroscience methods (01-01-2022)“…Deep Brain Stimulation (DBS) is an established treatment for motor symptoms in Parkinson’s disease (PD). However, side effects often limit the usefulness of…”
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UVB irradiation induces contralateral changes in galanin, substance P and c-fos immunoreactivity in rat dorsal root ganglia, dorsal horn and lateral spinal nucleus
Published in Peptides (New York, N.Y. : 1980) (01-02-2021)“…•Unilaterally UVB induced inflammation will change the contralateral expression of galanin, SP and c-fos in spinal cord dorsal horn, lateral spinal nucleus,…”
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Ice coating –A new method of brain device insertion to mitigate acute injuries
Published in Journal of neuroscience methods (01-09-2020)“…[Display omitted] •A new method enabling implantation of frozen devices into the brain is presented.•A coat of thawing ice on gelatin embedded needles strongly…”
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UVB irradiation induces rapid changes in galanin, substance P and c-fos immunoreactivity in rat dorsal root ganglia and spinal cord
Published in Peptides (New York, N.Y. : 1980) (01-01-2017)“…•UVB irradiation of rat hind paws will induce inflammation as reflected by an almost two-fold increase in skin blood flow after 24h.•UVB induced inflammation…”
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Markedly reduced chronic nociceptive response in mice lacking the PAC1 receptor
Published in Neuroreport (20-07-2001)“…The neuropeptide pituitary adenylate cyclase activating polypeptide (PACAP) has been proposed to have a role in nociception. Here we have used the formalin…”
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An array of highly flexible electrodes with a tailored configuration locked by gelatin during implantation-initial evaluation in cortex cerebri of awake rats
Published in Frontiers in neuroscience (2015)“…A major challenge in the field of neural interfaces is to overcome the problem of poor stability of neuronal recordings, which impedes long-term studies of…”
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Altered behavioural responses and functional recovery in rats following sciatic nerve compression and early vs late decompression
Published in Journal of plastic surgery and hand surgery (01-11-2016)“…The aim of the study was to examine sensory behaviour and functional recovery in rats during nerve compression and after decompression. Compression injury is a…”
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Expression of orphanin FQ/nociceptin and its receptor in rat peripheral ganglia and spinal cord
Published in Brain research (02-08-2002)“…Expression of the neuropeptide orphanin FQ/nociceptin (OFQ/N) and its receptor, the opioid receptor-like receptor (ORL1), have been found to have a wide…”
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PACAP mRNA is expressed in rat spinal cord neurons
Published in Journal of comparative neurology (1911) (22-03-2004)“…This study examines the expression of pituitary adenylate cyclase activating polypeptide (PACAP) mRNA in the rat spinal cord during normal conditions and in…”
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