Search Results - "Pettenuzzo, Letícia F"

Methotrexate up-regulates ecto-5′-nucleotidase/CD73 and reduces the frequency of T lymphocytes in the glioblastoma microenvironment by Figueiró, Fabrício, de Oliveira, Catiúscia P., Bergamin, Letícia S., Rockenbach, Liliana, Mendes, Franciane B., Jandrey, Elisa Helena F., Moritz, Cesar Eduardo J., Pettenuzzo, Letícia F., Sévigny, Jean, Guterres, Silvia S., Pohlmann, Adriana R., Battastini, Ana Maria O.

“…Glioblastoma multiforme (GBM) is a deadly cancer characterized by a pro-tumoral immune response. T-regulatory (Treg) lymphocytes suppress effector immune cells…”
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Effects of intranasal guanosine administration on brain function in a rat model of ischemic stroke by Müller, Gabriel C., Loureiro, Samanta O., Pettenuzzo, Letícia F., Almeida, Roberto F., Ynumaru, Evandro Y., Guazzelli, Pedro A., Meyer, Fabíola S., Pasquetti, Mayara V., Ganzella, Marcelo, Calcagnotto, Maria Elisa, Souza, Diogo O.

“…Ischemic stroke is a major cause of morbidity and mortality worldwide and only few affected patients are able to receive treatment, especially in developing…”
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Effect of chronic administration of tamoxifen and/or estradiol on feeding behavior, palatable food and metabolic parameters in ovariectomized rats by Lampert, Carine, Arcego, Danusa Mar, Laureano, Daniela P, Diehl, Luísa A, da Costa Lima, Isadora Ferreira, Krolow, Rachel, Pettenuzzo, Letícia F, Dalmaz, Carla, Vendite, Deusa

“…Abstract Tamoxifen (TAM) is a selective estrogen receptor modulator (SERM) used in the treatment of breast cancer; however many women complain of weight gain…”
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Resveratrol Induces Pro-oxidant Effects and Time-Dependent Resistance to Cytotoxicity in Activated Hepatic Stellate Cells by Martins, Leo A. Meira, Coelho, Bárbara P., Behr, Guilherme, Pettenuzzo, Letícia F., Souza, Izabel C. C., Moreira, José Cláudio F., Borojevic, Radovan, Gottfried, Carmem, Guma, Fátima Costa Rodrigues

“…Resveratrol (RSV) is known for its antioxidant properties; however, this compound has been proposed to have cytotoxic and pro-oxidant effects depending on its…”
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Amyloid-β induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action by Kreutz, Fernando, Frozza, Rudimar L., Breier, Ana Carolina, de Oliveira, Valeska A., Horn, Ana Paula, Pettenuzzo, Letícia F., Netto, Carlos Alexandre, Salbego, Christianne Gazzana, Trindade, Vera Maria Treis

“…► Aβ25–35 affected ganglioside expression in organotypic hippocampal cultures. ► Fibrillar Aβ25–35 increased GM3 labeling and reduced GD1b labeling. ►…”
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The effect of unpredictable chronic mild stress on depressive-like behavior and on hippocampal A1 and striatal A2A adenosine receptors by Crema, Leonardo M, Pettenuzzo, Letícia F, Schlabitz, Michele, Diehl, Luisa, Hoppe, Juliana, Mestriner, Régis, Laureano, Daniela, Salbego, Christianne, Dalmaz, Carla, Vendite, Deusa

“…Abstract This study examined the effects of two chronic stress regimens upon depressive-like behavior, A1 and A2A adenosine receptor binding and immunocontent…”
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1,25-dihydroxyvitamin D3 prevents deleterious effects of homocysteine on mitochondrial function and redox status in heart slices by Longoni, Aline, Kolling, Janaina, Siebert, Cassiana, dos Santos, João Paulo, da Silva, Jussemara Souza, Pettenuzzo, Letícia F, Meira-Martins, Leo Anderson, Gonçalves, Carlos-Alberto, de Assis, Adriano M, Wyse, Angela TS

“…Abstract Since homocysteine (Hcy) is a risk factor for cardiovascular disease and vitamin D deficiency can contribute to cardiovascular pathologies, in the…”
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Methylphenidate Causes Behavioral Impairments and Neuron and Astrocyte Loss in the Hippocampus of Juvenile Rats by Schmitz, Felipe, Pierozan, Paula, Rodrigues, André F., Biasibetti, Helena, Grunevald, Matheus, Pettenuzzo, Letícia F., Scaini, Giselli, Streck, Emilio L., Netto, Carlos A., Wyse, Angela T. S.

“…Although the use, and misuse, of methylphenidate is increasing in childhood and adolescence, there is little information about the consequences of this…”
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Maternal Hypermethioninemia Affects Neurons Number, Neurotrophins Levels, Energy Metabolism, and Na+,K+-ATPase Expression/Content in Brain of Rat Offspring by Schweinberger, Bruna M., Rodrigues, André F., Turcatel, Elias, Pierozan, Paula, Pettenuzzo, Leticia F., Grings, Mateus, Scaini, Giselli, Parisi, Mariana M., Leipnitz, Guilhian, Streck, Emilio L., Barbé-Tuana, Florencia M., Wyse, Angela T. S.

“…In the current study, we verified the effects of maternal hypermethioninemia on the number of neurons, apoptosis, nerve growth factor, and brain-derived…”
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Neonatal hypoxia-ischemia induces sex-related changes in rat brain mitochondria by Weis, Simone N, Pettenuzzo, Leticia F, Krolow, Rachel, Valentim, Lauren M, Mota, Carina S, Dalmaz, Carla, Wyse, Angela T S, Netto, Carlos Alexandre

“…The effects of neonatal hypoxia-ischemia (HI) on energy metabolism in male and female rats were investigated, testing the hypothesis that HI-induced brain…”
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Early biochemical effects after unilateral hypoxia–ischemia in the immature rat brain by Weis, Simone N., Schunck, Rebeca V.A., Pettenuzzo, Leticia F., Krolow, Rachel, Matté, Cristiane, Manfredini, Vanusa, Peralba, Maria do Carmo R., Vargas, Carmen R., Dalmaz, Carla, Wyse, Angela T.S., Netto, Carlos A.

“…Perinatal hypoxia–ischemia (HI) gives rise to inadequate substrate supply to the brain tissue, resulting in damage to neural cells. Previous studies at…”
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Acute renal failure potentiates brain energy dysfunction elicited by methylmalonic acid by Schuck, Patrícia F., Januário, Silvana B., Simon, Kellen R., Scaini, Giselli, Mafioleti, Renato L., Malgarin, Fernanda, Pettenuzzo, Leticia F., Streck, Emilio L., Ferreira, Gustavo C.

“…► Methylmalonic acid (MMA) accumulates in methylmalonic acidemia. ► Affected patients present brain damage and renal insufficiency whose pathogenesis is poorly…”
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Differential inhibitory effects of methylmalonic acid on respiratory chain complex activities in rat tissues by Pettenuzzo, Leticia F., Ferreira, Gustavo da C., Schmidt, Anna Laura, Dutra‐Filho, Carlos S., Wyse, Angela T.S., Wajner, Moacir

“…Methylmalonic acidemia is an inherited metabolic disorder biochemically characterized by tissue accumulation of methylmalonic acid (MMA) and clinically by…”
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Modulation of the chelatable Zn pool in the brain by diethyldithiocarbamate is associated with behavioral impairment in adult zebrafish by Braga, Marcos M., Silva, Emerson S., Rico, Eduardo P., Pettenuzzo, Leticia F., Oliveira, Diogo L., Dias, Renato D., Rocha, João B. T., Calcagnotto, Maria Elisa, Tanguay, Robert L., Souza, Diogo O., Rosemberg, Denis B.

“…The study of the effects of diethyldithiocarbamate (DEDTC) in some diseases has been in focus for many years. However, DEDTC is a metal chelator that can…”
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Evaluation of the effect of chronic administration of drugs on rat behavior in the water maze task by Pettenuzzo, Leticia F, Wyse, Angela T.S, Wannmacher, Clóvis M.D, Dutra-Filho, Carlos S, Netto, Carlos Alexandre, Wajner, Moacir

“…Tissue accumulation of intermediates of the metabolism occurs in various inherited neurodegenerative disorders, including methylmalonic acidemia (MA). Animal…”
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Ascorbic acid prevents cognitive deficits caused by chronic administration of propionic acid to rats in the water maze by Pettenuzzo, Leticia F, Schuck, Patrı́cia F, Fontella, Fernanda, Wannmacher, Clóvis M.D, Wyse, Ângela T, Dutra-Filho, Carlos S, Netto, Carlos Alexandre, Wajner, Moacir

“…Propionic acidemia is an inherited neurometabolic disorder characterized by progressive neurological deterioration with psychomotor delay/mental retardation,…”
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Ascorbic acid prevents water maze behavioral deficits caused by early postnatal methylmalonic acid administration in the rat by Pettenuzzo, Leticia F., Schuck, Patrı́cia F., Wyse, Angela T.S., Wannmacher, Clóvis M.D., Dutra-Filho, Carlos S., Netto, Carlos Alexandre, Wajner, Moacir

“…Methylmalonic acidemia consists of a group of inherited neurometabolic disorders biochemically characterized by accumulation of methylmalonic acid (MA) and…”
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1,25-Dihydroxyvitamin D 3 prevents deleterious effects of homocysteine on mitochondrial function and redox status in heart slices by Longoni, Aline, Kolling, Janaina, Siebert, Cassiana, Dos Santos, João Paulo, da Silva, Jussemara Souza, Pettenuzzo, Letícia F, Meira-Martins, Leo Anderson, Gonçalves, Carlos-Alberto, de Assis, Adriano M, Wyse, Angela T S

“…Because homocysteine (Hcy) is a risk factor for cardiovascular disease, and vitamin D deficiency can contribute to cardiovascular pathologies. In the present…”
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Amyloid-[beta] induced toxicity involves ganglioside expression and is sensitive to GM1 neuroprotective action by Kreutz, Fernando, Frozza, Rudimar L, Breier, Ana Carolina, Oliveira, Valeska Ade, Horn, Ana Paula, Pettenuzzo, Leticia F, Netto, Carlos Alexandre, Salbego, Christianne Gazzana, Trindade, Vera Maria Treis

“…The effect of A[beta]25-35 peptide, in its fibrillar and non-fibrillar forms, on ganglioside expression in organotypic hippocampal slice cultures was…”
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Modulation of the chelatable Zn pool in the brain by diethyldithiocarbamate is associated with behavioral impairment in adult zebrafishElectronic supplementary information (ESI) available. Fig. S1: Calibration curve of absorbance and corresponding concentrations of DEDTC (mg mL−1). See DOI: 10.1039/c4tx00111g by Braga, Marcos M, Silva, Emerson S, Rico, Eduardo P, Pettenuzzo, Leticia F, Oliveira, Diogo L, Dias, Renato D, Rocha, João B. T, Calcagnotto, Maria Elisa, Tanguay, Robert L, Souza, Diogo O, Rosemberg, Denis B

“…The study of the effects of diethyldithiocarbamate (DEDTC) in some diseases has been in focus for many years. However, DEDTC is a metal chelator that can…”
Get full text