Search Results - "Petschner, Péter"

Genetic effects on educational attainment in Hungary by Ujma, Péter P., Eszlári, Nóra, Millinghoffer, András, Bruncsics, Bence, Török, Dóra, Petschner, Péter, Antal, Péter, Deakin, Bill, Breen, Gerome, Bagdy, György, Juhász, Gabriella

“…Introduction Educational attainment is a substantially heritable trait, and it has recently been linked to specific genetic variants by genome‐wide association…”
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Transcriptomic changes following chronic administration of selective serotonin reuptake inhibitors: a review of animal studies by Kumar, Sahel, Gal, Zsofia, Gonda, Xenia, Huse, Robin J, Juhasz, Gabriella, Bagdy, Gyorgy, Petschner, Peter

“…The review focuses on transcriptomic changes following treatment with serotonin reuptake inhibitor (SSRI) antidepressants. We aimed to overview results of the…”
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Differential adaptation of REM sleep latency, intermediate stage and theta power effects of escitalopram after chronic treatment by Vas, Szilvia, Kátai, Zita, Kostyalik, Diána, Pap, Dorottya, Molnár, Eszter, Petschner, Péter, Kalmár, Lajos, Bagdy, György

“…The effects of the widely used selective serotonin reuptake inhibitor (SSRI) antidepressants on sleep have been intensively investigated. However, only a few…”
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Chronic escitalopram treatment caused dissociative adaptation in serotonin (5-HT) 2C receptor antagonist-induced effects in REM sleep, wake and theta wave activity by Kostyalik, Diána, Kátai, Zita, Vas, Szilvia, Pap, Dorottya, Petschner, Péter, Molnár, Eszter, Gyertyán, István, Kalmár, Lajos, Tóthfalusi, László, Bagdy, Gyorgy

“…Several multi-target drugs used in treating psychiatric disorders, such as antidepressants (e.g. agomelatine, trazodone, nefazodone, amitriptyline,…”
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Antidepressant treatment response is modulated by genetic and environmental factors and their interactions by Kovacs, Dávid, Gonda, Xénia, Petschner, Péter, Edes, Andrea, Eszlari, Nóra, Bagdy, György, Juhasz, Gabriella

“…Although there is a wide variety of antidepressants with different mechanisms of action available, the efficacy of treatment is not satisfactory. Genetic…”
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Improved polygenic risk prediction in migraine-first patients by Torok, Dora, Petschner, Peter, Baksa, Daniel, Juhasz, Gabriella

“…Background Recent meta-analyses estimated 14.6% and 11.2% SNP-based heritability of migraine, compared to twin-heritability estimates of 30–60%. This study…”
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Transcriptional Evidence for the Role of Chronic Venlafaxine Treatment in Neurotrophic Signaling and Neuroplasticity Including also Glutatmatergic- and Insulin-Mediated Neuronal Processes by Tamási, Viola, Petschner, Peter, Adori, Csaba, Kirilly, Eszter, Ando, Romeo D, Tothfalusi, Laszlo, Juhasz, Gabriella, Bagdy, Gyorgy

“…Objectives Venlafaxine (VLX), a serotonine-noradrenaline reuptake inhibitor, is one of the most commonly used antidepressant drugs in clinical practice for the…”
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Acute 5-HT2C Receptor Antagonist SB-242084 Treatment Affects EEG Gamma Band Activity Similarly to Chronic Escitalopram by Papp, Noémi, Koncz, Szabolcs, Kostyalik, Diána, Kitka, Tamás, Petschner, Péter, Vas, Szilvia, Bagdy, György

“…Serotonin 2C receptors (5-HT 2C Rs) are implicated in the pathomechanism and treatment of anxiety and depression. Recently, as a new biomarker of depression,…”
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A replication study separates polymorphisms behind migraine with and without depression by Petschner, Peter, Baksa, Daniel, Hullam, Gabor, Torok, Dora, Millinghoffer, Andras, Deakin, J F William, Bagdy, Gyorgy, Juhasz, Gabriella

“…The largest migraine genome-wide association study identified 38 candidate loci. In this study we assessed whether these results replicate on a gene level in…”
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P2RX7 gene variation mediates the effect of childhood adversity and recent stress on the severity of depressive symptoms by Kristof, Zsuliet, Eszlari, Nora, Sutori, Sara, Gal, Zsofia, Torok, Dora, Baksa, Daniel, Petschner, Peter, Sperlagh, Beata, Anderson, Ian M, Deakin, John Francis William, Juhasz, Gabriella, Bagdy, Gyorgy, Gonda, Xenia

“…The P2X purinoceptor 7 (P2RX7) mediates inflammatory microglial responses and is implicated in neuroimmune mechanisms of depression and neurodegenerative…”
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Variation along P2RX7 interacts with early traumas on severity of anxiety suggesting a role for neuroinflammation by Kristof, Zsuliet, Gal, Zsofia, Torok, Dora, Eszlari, Nora, Sutori, Sara, Erdelyi-Hamza, Berta, Petschner, Peter, Sperlagh, Beata, Anderson, Ian M., Deakin, John Francis William, Bagdy, Gyorgy, Juhasz, Gabriella, Gonda, Xenia

“…Emotional stress is a leading risk factor in the development of neuropsychiatric disorders possibly via immune activation. P2X7 receptors promote…”
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Genetic risk of depression is different in subgroups of dietary ratio of tryptophan to large neutral amino acids by Bruncsics, Bence, Hullam, Gabor, Bolgar, Bence, Petschner, Peter, Millinghoffer, Andras, Gecse, Kinga, Eszlari, Nora, Gonda, Xenia, Jones, Debra J., Burden, Sorrel T., Antal, Peter, Deakin, Bill, Bagdy, Gyorgy, Juhasz, Gabriella

“…Manipulation of intake of serotonin precursor tryptophan has been exploited to rapidly induce and alleviate depression symptoms. While studies show that this…”
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Genetic underpinnings of affective temperaments: a pilot GWAS investigation identifies a new genome-wide significant SNP for anxious temperament in ADGRB3 gene by Gonda, Xenia, Eszlari, Nora, Torok, Dora, Gal, Zsofia, Bokor, Janos, Millinghoffer, Andras, Baksa, Daniel, Petschner, Peter, Antal, Peter, Breen, Gerome, Juhasz, Gabriella, Bagdy, Gyorgy

“…Although recently a large-sample GWASs identified significant loci in the background of depression, the heterogeneity of the depressive phenotype and the lack…”
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Effects of Different Stressors Are Modulated by Different Neurobiological Systems: The Role of GABA-A Versus CB1 Receptor Gene Variants in Anxiety and Depression by Gonda, Xenia, Petschner, Peter, Eszlari, Nora, Sutori, Sara, Gal, Zsofia, Koncz, Szabolcs, Anderson, Ian M, Deakin, Bill, Juhasz, Gabriella, Bagdy, Gyorgy

“…Environmental stress and its interaction with genetic variation are key contributors in the development of depression and anxiety, yet there is a failure to…”
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Biology of Perseverative Negative Thinking: The Role of Timing and Folate Intake by Eszlari, Nora, Bruncsics, Bence, Millinghoffer, Andras, Hullam, Gabor, Petschner, Peter, Gonda, Xenia, Breen, Gerome, Antal, Peter, Bagdy, Gyorgy, Deakin, John Francis William, Juhasz, Gabriella

“…Past-oriented rumination and future-oriented worry are two aspects of perseverative negative thinking related to the neuroticism endophenotype and associated…”
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Gene expression analysis indicates reduced memory and cognitive functions in the hippocampus and increase in synaptic reorganization in the frontal cortex 3 weeks after MDMA administration in Dark Agouti rats by Petschner, Peter, Tamasi, Viola, Adori, Csaba, Kirilly, Eszter, Ando, Romeo D, Tothfalusi, Laszlo, Bagdy, Gyorgy

“…3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") is a widely used entactogenic drug known to impair cognitive functions on the long-run. Both hippocampal…”
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Inflamed Mind: Multiple Genetic Variants of IL6 Influence Suicide Risk Phenotypes in Interaction With Early and Recent Adversities in a Linkage Disequilibrium-Based Clumping Analysis by Bokor, Janos, Sutori, Sara, Torok, Dora, Gal, Zsofia, Eszlari, Nora, Gyorik, Dorka, Baksa, Daniel, Petschner, Peter, Serafini, Gianluca, Pompili, Maurizio, Anderson, Ian M., Deakin, Bill, Bagdy, Gyorgy, Juhasz, Gabriella, Gonda, Xenia

“…Background: Understanding and predicting suicide remains a challenge, and a recent paradigm shift regarding the complex relationship between the immune system…”
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Variability in the effect of 5-HTTLPR on depression in a large European population: the role of age, symptom profile, type and intensity of life stressors by Juhasz, Gabriella, Gonda, Xenia, Hullam, Gabor, Eszlari, Nora, Kovacs, David, Lazary, Judit, Pap, Dorottya, Petschner, Peter, Elliott, Rebecca, Deakin, John Francis William, Anderson, Ian Muir, Antal, Peter, Lesch, Klaus-Peter, Bagdy, Gyorgy

“…Although 5-HTTLPR has been shown to influence the risk of life stress-induced depression in the majority of studies, others have produced contradictory…”
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Every Night and Every Morn: Effect of Variation in CLOCK Gene on Depression Depends on Exposure to Early and Recent Stress by Gyorik, Dorka, Eszlari, Nora, Gal, Zsofia, Torok, Dora, Baksa, Daniel, Kristof, Zsuliet, Sutori, Sara, Petschner, Peter, Juhasz, Gabriella, Bagdy, Gyorgy, Gonda, Xenia

“…The role of circadian dysregulation is increasingly acknowledged in the background of depressive symptoms, and is also a promising treatment target. Similarly,…”
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Downregulation of the Vitamin D Receptor Regulated Gene Set in the Hippocampus After MDMA Treatment by Petschner, Peter, Balogh, Noemi, Adori, Csaba, Tamasi, Viola, Kumar, Sahel, Juhasz, Gabriella, Bagdy, Gyorgy

“…The active ingredient of ecstasy, ±3,4-methylenedioxymethamphetamine (MDMA), in addition to its initial reinforcing effects, induces selective and…”
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