Search Results - "Petruska, Jeffrey C."

Early heart failure in the SMNΔ7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery by Bevan, Adam K., Hutchinson, Kirk R., Foust, Kevin D., Braun, Lyndsey, McGovern, Vicki L., Schmelzer, Leah, Ward, Jennifer G., Petruska, Jeffrey C., Lucchesi, Pamela A., Burghes, Arthur H.M., Kaspar, Brian K.

“…Proximal spinal muscular atrophy (SMA) is a debilitating neurological disease marked by isolated lower motor neuron death and subsequent atrophy of skeletal…”
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Framework for reanalysis of publicly available Affymetrix® GeneChip® data sets based on functional regions of interest by Saka, Ernur, Harrison, Benjamin J, West, Kirk, Petruska, Jeffrey C, Rouchka, Eric C

“…Since the introduction of microarrays in 1995, researchers world-wide have used both commercial and custom-designed microarrays for understanding differential…”
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Organization of sensory input to the nociceptive-specific cutaneous trunk muscle reflex in rat, an effective experimental system for examining nociception and plasticity by Petruska, Jeffrey C., Barker, Darrell F., Garraway, Sandra M., Trainer, Robert, Fransen, James W., Seidman, Peggy A., Soto, Roy G., Mendell, Lorne M., Johnson, Richard D.

“…ABSTRACT Detailed characterization of neural circuitries furthers our understanding of how nervous systems perform specific functions and allows the use of…”
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Changes in Motoneuron Properties and Synaptic Inputs Related to Step Training after Spinal Cord Transection in Rats by Petruska, Jeffrey C, Ichiyama, Ronaldo M, Jindrich, Devin L, Crown, Eric D, Tansey, Keith E, Roy, Roland R, Edgerton, V. Reggie, Mendell, Lorne M

“…Although recovery from spinal cord injury is generally meager, evidence suggests that step training can improve stepping performance, particularly after…”
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Detection of Differentially Expressed Cleavage Site Intervals Within 3' Untranslated Regions Using CSI-UTR Reveals Regulated Interaction Motifs by Harrison, Benjamin J, Park, Juw Won, Gomes, Cynthia, Petruska, Jeffrey C, Sapio, Matthew R, Iadarola, Michael J, Chariker, Julia H, Rouchka, Eric C

“…The length of untranslated regions at the 3' end of transcripts (3'UTRs) is regulated by alternate polyadenylation (APA). 3'UTRs contain regions that harbor…”
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The many functions of nerve growth factor: multiple actions on nociceptors by Petruska, Jeffrey C., Mendell, Lorne M.

“…Nerve growth factor (NGF) initially interested neurobiologists because of its effects in the developing nervous system. It is now clear that NGF functions…”
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BDNF sensitizes the response of lamina II neurons to high threshold primary afferent inputs by Garraway, Sandra M., Petruska, Jeffrey C., Mendell, Lorne M.

“…Brain‐derived neurotrophic factor (BDNF) is up‐regulated and released in the dorsal horn following peripheral inflammation and has therefore been implicated in…”
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Skin incision induces expression of axonal regeneration-related genes in adult rat spinal sensory neurons by Hill, Caitlin E, Harrison, Benjamin J, Rau, Kris K, Hougland, M Tyler, Bunge, Mary Bartlett, Mendell, Lorne M, Petruska, Jeffrey C

“…Skin incision and nerve injury both induce painful conditions. Incisional and postsurgical pain is believed to arise primarily from inflammation of tissue and…”
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AbsIDconvert: an absolute approach for converting genetic identifiers at different granularities by Mohammad, Fahim, Flight, Robert M, Harrison, Benjamin J, Petruska, Jeffrey C, Rouchka, Eric C

“…High-throughput molecular biology techniques yield vast amounts of data, often by detecting small portions of ribonucleotides corresponding to specific…”
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Subclassified Acutely Dissociated Cells of Rat DRG: Histochemistry and Patterns of Capsaicin-, Proton-, and ATP-Activated Currents by Petruska, Jeffrey C, Napaporn, Jintana, Johnson, Richard D, Gu, Jianguo G, Cooper, Brian Y

“…  1 Department of Physiological Sciences, College of Veterinary Medicine, University of Florida;   2 Department of Oral Surgery and Diagnostic Sciences,…”
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Challenges and opportunities of sensory plasticity after SCI by Petruska, Jeffrey C, Hubscher, Charles H, Rabchevsky, Alexander G

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A Developmental Switch in Acute Sensitization of Small Dorsal Root Ganglion (DRG) Neurons to Capsaicin or Noxious Heating by NGF by Zhu, Weiguo, Galoyan, Sam M, Petruska, Jeffrey C, Oxford, Gerry S, Mendell, Lorne M

“…1 Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana 46202; and 2 Department of Neurobiology and Behavior,…”
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The Transcriptional Response of Neurotrophins and Their Tyrosine Kinase Receptors in Lumbar Sensorimotor Circuits to Spinal Cord Contusion is Affected by Injury Severity and Survival Time by Hougland, M Tyler, Harrison, Benjamin J, Magnuson, David S K, Rouchka, Eric C, Petruska, Jeffrey C

“…Traumatic spinal cord injury (SCI) results in changes to the anatomical, neurochemical, and physiological properties of cells in the central and peripheral…”
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Transcriptional changes in sensory ganglia associated with primary afferent axon collateral sprouting in spared dermatome model by Harrison, Benjamin J., Venkat, Gayathri, Hutson, Thomas, Rau, Kristofer K., Bunge, Mary Bartlett, Mendell, Lorne M., Gage, Fred H., Johnson, Richard D., Hill, Caitlin, Rouchka, Eric C., Moon, Lawrence, Petruska, Jeffrey C.

“…Primary afferent collateral sprouting is a process whereby non-injured primary afferent neurons respond to some stimulus and extend new branches from existing…”
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Construction of a Searchable Database for Gene Expression Changes in Spinal Cord Injury Experiments by Rouchka, Eric C, de Almeida, Carlos, House, Randi B, Daneshmand, Jonah C, Chariker, Julia H, Saraswat-Ohri, Sujata, Gomes, Cynthia, Sharp, Morgan, Shum-Siu, Alice, Cesarz, Greta M, Petruska, Jeffrey C, Magnuson, David S K

“…Spinal cord injury (SCI) is a debilitating condition with an estimated 18,000 new cases annually in the United States. The field has accepted and adopted…”
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Combining clinically common drugs with hindlimb stretching in spinal cord injured rodents by Forston, Morgan J., Jordan, Savannah L., Cesarz, Greta M., Burke, Darlene A., Shum-Siu, Alice, Petruska, Jeffrey C., Magnuson, David S. K.

“…Study design Preclinical pilot study. Objectives To explore peripheral and central nociceptive mechanisms that contribute to muscle stretch-induced locomotor…”
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Broad opioid antagonism amplifies disruption of locomotor function following therapy-like hindlimb stretching in spinal cord injured rats by States, Gregory J. R., Keller, Anastasia, Shum-Siu, Alice, Petruska, Jeffrey C., Magnuson, David S. K.

“…Study design Preclinical pilot study. Objectives To test the hypothesis that spinal opioidergic circuitry contributes to muscle stretch-induced locomotor…”
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Differential expression of ryanodine receptor isoforms after spinal cord injury by Pelisch, Nicolas, Gomes, Cynthia, Nally, Jacqueline M., Petruska, Jeffrey C., Stirling, David P.

“…•RyR2 and RyR3 are upregulated in dorsal root ganglion neurons acutely after SCI.•RyR2 and RyR3 are upregulated in the lesion site after SCI.•RyR1 remained…”
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Identification of bladder and colon afferents in the nodose ganglia of male rats by Herrity, April N., Rau, Kristofer K., Petruska, Jeffrey C., Stirling, David P., Hubscher, Charles H.

“…ABSTRACT The sensory neurons innervating the urinary bladder and distal colon project to similar regions of the central nervous system and often are affected…”
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Delayed intramuscular human neurotrophin-3 improves recovery in adult and elderly rats after stroke by Duricki, Denise A, Hutson, Thomas H, Kathe, Claudia, Soleman, Sara, Gonzalez-Carter, Daniel, Petruska, Jeffrey C, Shine, H David, Chen, Qin, Wood, Tobias C, Bernanos, Michel, Cash, Diana, Williams, Steven C R, Gage, Fred H, Moon, Lawrence D F

“…There is an urgent need for a therapy that reverses disability after stroke when initiated in a time frame suitable for the majority of new victims. We show…”
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