Search Results - "Petrushova, Lidiya A"

Synthesis, Spatial Structure and Analgesic Activity of Sodium 3-Benzylaminocarbonyl-1-methyl-2,2-dioxo-1H-2λ⁶,1-benzothiazin-4-olate Solvates by Ukrainets, Igor V, Petrushova, Lidiya A, Shishkina, Svitlana V, Grinevich, Lina A, Sim, Galina

“…In order to obtain and then test pharmocologically any possible conformers of the new feasible analgesic benzyl-4-hydroxy-1-methyl-2,2-dioxo-1…”
Get full text

Biological properties of two enantiomorphic forms of N‐(2,6‐dimethylphenyl)‐4‐hydroxy‐2,2‐dioxo‐1H‐2λ6,1‐benzothiazine‐3‐carboxamide, a structural analogue of piroxicam by Shishkina, Svitlana V., Ukrainets, Igor V., Vashchenko, Olga V., Voloshchuk, Natali I., Bondarenko, Pavlo S., Petrushova, Lidiya A., Sim, Galina

“…The title benzothiazine‐3‐carboxamide, C17H16N2O4S, crystallized in two enantiomorphic crystal forms with the space groups P32 and P31 despite the absence of a…”
Get full text

Methyl 5-chloro-4-hy-droxy-2,2-dioxo-1H-2λ6,1-benzo-thia-zine-3-carboxyl-ate: structure and Hirshfeld surface analysis by Shishkina, Svitlana V, Petrushova, Lidiya A, Burian, Kateryna O, Fedosov, Andrii I, Ukrainets, Igor V

“…The title compound, C10H8ClNO5S, which has potential analgesic activity, crystallizes in space group P21/n. The benzo-thia-zine ring system adopts an…”
Get full text

Crystal Habits and Biological Properties of N-(4-Trifluoromethylphenyl)-4-Hydroxy-2,2-Dioxo-1H-2λ6,1-Benzothiazine-3-Carboxamide by Ukrainets, Igor V., Petrushova, Lidiya A., Fedosov, Andrii I., Voloshchuk, Natali I., Bondarenko, Pavlo S., Shishkina, Svitlana V., Sidorenko, Lyudmila V., Sim, Galina

“…In order to study polymorphic modifications of N-(4-trifluoromethylphenyl)-4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxamide, which is of interest as a…”
Get full text

The Effective Synthesis of N-(Arylalkyl)-1-R-4-hydroxy-2,2-dioxo- 1H-2λ(6),1-benzothiazine-3-carboxamides as Promising Analgesics of a New Chemical Class by Ukrainets, Igor V, Petrushova, Lidiya A, Dzyubenko, Sergiy P, Sim, Galina, Grinevich, Lina A

“…A new, effective preparative method has been proposed and the synthesis of a series of…”
Get full text

Two pseudo-enantiomeric forms of N-benzyl-4-hydroxy-1-methyl-2,2-dioxo-1H-2λ(6),1-benzothiazine-3-carboxamide and their analgesic properties by Ukrainets, Igor V, Shishkina, Svitlana V, Baumer, Vyacheslav N, Gorokhova, Olga V, Petrushova, Lidiya A, Sim, Galina

“…The fact that molecular crystals exist as different polymorphic modifications and the identification of as many polymorphs as possible are important…”
Get full text

Methyl 4-Hydroxy-2,2-Dioxo-1H-2λ6,1-Benzothiazine-3-Carboxylate and Its Analogs Modified in the Benzene Moiety of the Molecule as New Analgesics by Ukrainets, Igor V., Petrushova, Lidiya A., Shishkina, Svitlana V., Sidorenko, Lyudmila V., Alekseeva, Tatiana V., Torianyk, Inna I., Davidenko, Alexandra A.

“…In order to identify new regularities of the “structure–analgesic activity” relationship in the series of 2,1-benzothiazine derivatives, the synthesis of…”
Get full text

( R , S )-2′-Amino-6′-methyl-2,5′,5′-trioxo-6′ H -spiro[indoline-3,4′-pyrano[3,2- c ][2,1]benzothiazine]-3′-carbonitrile dimethylformamide monosolvate by Shishkina, Svitlana V., Ukrainets, Igor V., Petrushova, Lidiya A.

“…The title solvate, C 20 H 14 N 4 O 4 S·C 3 H 7 NO, comprises a stereogenic centre but the centrosymmetric space group causes the presence of the racemate in…”
Get full text

The Study of Structure-Analgesic Activity Relationships in a Series of 4-Hydroxy-2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxylic Acid Toluidides and Xylidides by Ukrainets, Igor V, Petrushova, Lidiya A, Sidorenko, Lyudmila V, Davidenko, Alexandra A, Duchenko, Marina A

“…In continuing the search for new analgesics among derivatives of 2,1-benzothiazines, a series of corresponding toluidides and xylidides of…”
Get full text

Synthesis, Structure, and Analgesic Properties of Halogen-Substituted 4-Hydroxy-2,2-dioxo-1H-2λ⁶,1-benzothiazine-3-carboxanilides by Ukrainets, Igor V, Petrushova, Lidiya A, Shishkina, Svitlana V, Sidorenko, Lyudmila V, Sim, Galina, Kryvanych, Olga V

“…As potential new analgesics, the corresponding 4-hydroxy-2,2-dioxo-1 -2λ⁶,1-benzothiazine-3-carboxanilides have been obtained by amidation of ethyl…”
Get full text

Methyl 5-chloro-4-hydroxy-2,2-dioxo-1H-2λ6,1-benzothiazine-3-carboxylate: structure and Hirshfeld surface analysis by Svitlana V. Shishkina, Lidiya A. Petrushova, Kateryna O. Burian, Andrii I. Fedosov, Igor V. Ukrainets

“…The title compound, C10H8ClNO5S, which has potential analgesic activity, crystallizes in space group P21/n. The benzothiazine ring system adopts an…”
Get full text

Methyl 5-chloro-4-hydroxy-2,2-dioxo-1 H -2λ 6 ,1-benzothiazine-3-carboxylate: structure and Hirshfeld surface analysis by Shishkina, Svitlana V., Petrushova, Lidiya A., Burian, Kateryna O., Fedosov, Andrii I., Ukrainets, Igor V.

“…The title compound, C 10 H 8 ClNO 5 S, which has potential analgesic activity, crystallizes in space group P 2 1 / n . The benzothiazine ring system adopts an…”
Get full text

Biological properties of two enantiomorphic forms of N -(2,6-dimethylphenyl)-4-hydroxy-2,2-dioxo-1 H -2λ 6 ,1-benzothiazine-3-carboxamide, a structural analogue of piroxicam by Shishkina, Svitlana V., Ukrainets, Igor V., Vashchenko, Olga V., Voloshchuk, Natali I., Bondarenko, Pavlo S., Petrushova, Lidiya A., Sim, Galina

“…The title benzothiazine-3-carboxamide, C 17 H 16 N 2 O 4 S, crystallized in two enantiomorphic crystal forms with the space groups P 3 2 and P 3 1 despite the…”
Get full text

Biological properties of two enantiomorphic forms of N-(2,6-dimethylphenyl)-4-hydroxy-2,2-dioxo-1H-2λ 6 ,1-benzothiazine-3-carboxamide, a structural analogue of piroxicam by Shishkina, Svitlana V, Ukrainets, Igor V, Vashchenko, Olga V, Voloshchuk, Natali I, Bondarenko, Pavlo S, Petrushova, Lidiya A, Sim, Galina

“…The title benzothiazine-3-carboxamide, C H N O S, crystallized in two enantiomorphic crystal forms with the space groups P3 and P3 despite the absence of a…”
Get full text

Synthesis, Spatial Structure and Analgesic Activity of Sodium 3-Benzylaminocarbonyl-1-methyl-2,2-dioxo-1H-2[lamda]^sup 6^,1-benzothiazin-4-olate Solvates by Ukrainets, Igor V, Petrushova, Lidiya A, Shishkina, Svitlana V, Grinevich, Lina A, Sim, Galina

Get full text

The Study of Structure-Analgesic Activity Relationships in a Series of 4-Hydroxy-2,2-dioxo-1H-2[lamda]^sup 6^,1-benzothiazine-3-carboxylic Acid Toluidides and Xylidides by Ukrainets, Igor V, Petrushova, Lidiya A, Sidorenko, Lyudmila V, Davidenko, Alexandra A, Duchenko, Marina A

Get full text

The Effective Synthesis of N-(Arylalkyl)-1-R-4-hydroxy-2,2-dioxo- 1H-2[lamda]^sup 6^,1-benzothiazine-3-carboxamides as Promising Analgesics of a New Chemical Class by Ukrainets, Igor V, Petrushova, Lidiya A, Dzyubenko, Sergiy P, Sim, Galina, Grinevich, Lina A

Get full text

Synthesis, Structure, and Analgesic Properties of Halogen-Substituted 4-Hydroxy-2,2-dioxo-1H-2[lamda]^sup 6^, 1-benzothiazine-3-carboxanilides by Ukrainets, Igor V, Petrushova, Lidiya A, Shishkina, Svitlana V, Sidorenko, Lyudmila V, Sim, Galina, Kryvanych, Olga V

Get full text

The Effective Synthesis of N-(Arylalkyl)-1-R-4-hydroxy-2,2-dioxo- 1H-2λ6,1-benzothiazine-3-carboxamides as Promising Analgesics of a New Chemical Class by Ukrainets, Igor V., Petrushova, Lidiya A., Dzyubenko, Sergiy P., Sim, Galina, Grinevich, Lina A.

“…A new, effective preparative method has been proposed and the synthesis of a series of N -(arylalkyl)-1-R-4-hydroxy-2,2-dioxo-1 H -2λ 6…”
Get full text

2,1-Benzothiazine 2,2-dioxides 10. Reaction of alkyl 1-R-4-hydroxy-2,2-dioxo-1Ð-2[lambda].sup.6,1-benzothiazine-3-carboxylates with 1H-1,2,4-triazol-5-amine by Ukrainets, Igor V, Petrushova, Lidiya A, Sim, Galina, Bereznyakova, Natalya L

“…The reaction of alkyl 1-R-4-hydroxy-2,2-dioxo-1Ð-2[lambda].sup.6,1-benzothiazine-3-carboxylates with 1H-1,2,4-triazol-5-amine in refluxing xylene produced not…”
Get full text