Search Results - "Petrusewicz, J"

Antiaggregatory activity of hypoglycaemic sulphonylureas by SILUK, D, KALISZAN, R, HABER, P, PETRUSEWICZ, J, BRZOZOWSKI, Z, SUT, G

“…Vascular complications observed in diabetes are often related to altered platelet functions. The most widely used hypoglycaemic drugs for treating Type II…”
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New galanin(1-15) analogues modified in positions 9, 10 and 11 act as galanin antagonists on glucose-induced insulin secretion by Olkowicz, M, Ruczyński, J, Cybal, M, Konstański, Z, Petrusewicz, J, Kamińska, B, Rekowski, P

“…Galanin (GAL) is a 29-amino-acid residue peptide originally isolated from porcine upper small intestine. GAL exhibits various physiological activities, such as…”
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Salutary effects of tachykinin receptor antagonists in a rat model of postoperative ileus by CIECHANOWNICZ, R, SEIN-ANAND, J, CHODOROWSKI, Z, BITEL, M, PETRUSEWICZ, J, KOROLKIEWICZ, R. P

“…Postoperative ileus (PI) is a common surgical complication treated mainly with supportive measures. Tachykinins control gastrointestinal motility and modulate…”
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The role and interactions of nitric oxide (NO), carbon monoxide (CO), and prostanoids in the pathogenesis of postoperative ileus in rats by Korolkiewicz, R.P., Sein-Anand, J., Ruczyński, J., Rekowski, P., Bieniaszewski, L., Chodorowski, Z., Petrusewicz, J., Ujda, M., Dąbkowski, J., Bitel, M., Kato, S., Takeuchi, K.

“…The effects of heme oxygenase (HO) inhibitors, zinc-protoporphyrin-IX (ZnPP-IX), and tin protoporphyrin-IX (SnPP-IX) and their interactions with…”
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Synthesis and Hypolipidemic and Antiplatelet Activities of α-Asarone Isomers in Humans (in Vitro), Mice (in Vivo), and Rats (in Vivo) by Popławski, Janusz, Łozowicka, Bożena, Dubis, Alina T, Lachowska, Barbara, Witkowski, Stanisław, Siluk, Danuta, Petrusewicz, Jacek, Kaliszan, Roman, Cybulski, Jacek, Strzałkowska, Małgorzata, Chilmonczyk, Zdzisław

“…A series of α-asarone isomers was synthesized and investigated for their hypolipidemic and antiplatelet activity. Considering the hypolipidemic activity in…”
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The contractile effects of several substituted short analogues of porcine galanin in isolated rat jejunal and colonic smooth muscle strips by Umer, A., Ługowska, H., Sein-Anand, J., Rekowski, P., Ruczyński, J., Petrusewicz, J., Korolkiewicz, R.P.

“…The activity of short porcine galanin (Gal) analogues was tested in vitro using rat jejunal and colonic smooth muscle strips. Peptides evoked…”
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Synthesis and biological properties of new chimeric galanin analogue GAL(1-13)-[Ala10,11]ET-1(6-21)-NH2 by Ruczyński, J, Konstański, Z, Cybal, M, Petrusewicz, J, Wójcikowski, C, Rekowski, P, Kamińska, B

“…Several chimeric peptides consisting of the N-terminal fragment of galanin (GAL) and C-terminal fragments of other bioactive peptides (e.g. substance P,…”
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THE INHIBITORY EFFECTS OF TERIKALANT ON THE CONTRACTILE ACTIVITY OF GALANIN IN ISOLATED RAT FUNDUS STRIPS by KOROLKIEWICZ, R.P., KONSTAŃSKI, Z., REKOWSKI, P., RUCZYŃSKI, J., SZYK, A., SZCZEPAŃSKA, R., PETRUSEWICZ, J.

“…The maximal responses (Emaxs) of isolated rat gastric fundus strips to 300 nm porcine galanin (Gal) were decreased in a concentration-dependent manner by…”
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Actions of several substituted short analogues of porcine galanin on isolated rat fundus strips: a structure-activity relationship by Korolkiewicz, R P, Konstański, Z, Rekowski, P, Ruczyński, J, Szyk, A, Grzybowska, M, Korolkiewicz, K Z, Petrusewicz, J

“…The activity of porcine galanin (Gal) fragments and analogues were tested in vitro using rat gastric fundus strips. The peptides contracted longitudinal smooth…”
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Mydriasis in comparison with other adrenoceptor-mediated effects elicited by imidazol(in)E alpha2-adrenomimetics by Nasal, A., Frackowiak, T., Petrusewicz, J., Buciński, A., Kaliszan, R.

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Effect of imidazoline drugs on human blood platelet aggregation by Petrusewicz, J, Kaliszan, R

“…The effect of seven commonly used in therapy imidazoline derivatives on human blood platelet aggregation was studied. Three of the agents, i.e. clonidine,…”
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Synthesis and pharmacological activity of 5-substituted-s-triazole-3-thiols by Czarnocka-Janowicz, A, Foks, H, Nasal, A, Petrusewicz, J, Damasiewicz, B, Radwańska, A, Kaliszan, R

“…Two subgroups of 5-substituted triazoles were synthesized: derivatives of 3(3-substituted-amino-2-hydroxypropylthio)-5-substituted-4H-1,2,4- triazole and…”
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Antiaggregatory activity of imidazoline drugs and chemicals as a function of their structure by Petrusewicz, J, Kaliszan, R

“…The concentration-response curves were constructed for 18 azole derivatives (including seven imidazoline drugs) as the inhibitors of the adrenaline-induced…”
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Blood platelet adrenoceptor: aggregatory and antiaggregatory activity of imidazoline drugs by Petrusewicz, J, Kaliszan, R

“…The effects of seven commonly used imidazoline drugs on human blood platelet aggregation and their inhibitory activity against the adrenaline-induced process…”
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Synthesis, structure and biological activity of 1,2,4-triazolo-1,3-thiazine derivatives by Foks, H, Rudnicka, W, Głowka, M, Kaliszan, R, Nasal, A, Damasiewicz, B, Radwańska, A, Petrusewicz, J, Trzeciak, H, Okopień, B

“…A group of condensed triazole-thiazine derivatives (2a-i, 3b, 3j) was obtained in reaction of the corresponding 5-substituted 1,2,4-triazole-3-thiones (1a-j)…”
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Different mechanisms of positive chronotropic actions of isoprenaline and noradrenaline on isolated guinea pig right atria revealed by pretreatment with rilmakalim by Kocić, I, Dabrowski, M, Petrusewicz, J

“…In this study we tested the influence of activation of ATP-sensitive K+ channels (KATP) on the changes in automatism induced by isoprenaline, noradrenaline and…”
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Salutary Effects of Tachykinin Receptor Antagonists in a Rat Model of Postoperative Ileus 1 1 Results were presented in part at a Brain-Gut Axis in Gastrointestinal System. Basic and Clinical Aspects Symposium, Kraków, Poland, November 2003 by Ciechanownicz, R., Sein-Anand, J., Chodorowski, Z., Bitel, M., Petrusewicz, J., Korolkiewicz, R.P.

“…Postoperative ileus (PI) is a common surgical complication treated mainly with supportive measures. Tachykinins control gastrointestinal motility and modulate…”
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Differential salutary effects of nonselective and selective COX-2 inhibitors in postoperative ileus in rats by Korolkiewicz, Roman P., Ujda, Marek, Dąbkowski, Jarosław, Ruczyński, Jarosław, Rekowski, Piotr, Petrusewicz, Jacek

“…Background. Postoperative ileus (PI) is a common surgical complication, the treatment of which consists of supportive measures. Aim. The effects of several…”
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Antagonists of glycoprotein IIb/IIIa as new antiplatelet agents by Petrusewicz, J

“…Blood platelets play an essential role in arterial thrombosis. Platelets activation starts from their binding to membrane receptors what results in consecutive…”
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Short communication: Antiaggregatory activity of hypoglycaemic sulphonylureas by Siluk, D, Kaliszan, R, Haber, P, Petrusewicz, J, Brzozowski, Z, Sut, G

“…Abstract Aims/hypothesis. Vascular complications observed in diabetes are often related to altered platelet functions. The most widely used hypoglycaemic drugs…”
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