Search Results - "Petruseva, I O"

Photoactivated DNA analogs of substrates of the nucleotide excision repair system and their interaction with proteins of NER-competent extract of HeLa cells. Synthesis and application of long model DNA by Evdokimov, A. N, Petruseva, I. O, Pestryakov, P. E, Lavrik, O. I

“…Long linear DNA analogs of nucleotide excision repair (NER) substrates have been synthesized. They are 137-mer duplexes containing in their internal positions…”
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Recognition and removal of clustered DNA lesions via nucleotide excision repair by Naumenko, N.V., Petruseva, I.O., Lomzov, A.A., Lavrik, O.I.

“…Clustered damage of DNA consists of two or more lesions located within one or two turns of the DNA helix. Clusters consisting of lesions of various structures…”
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Synthetic Lesions with a Fluorescein Carbamoyl Group As Analogs of Bulky Lesions Removable by Nucleotide Excision Repair: A Comparative Study on Properties by Popov, A A, Golyshev, V M, Koroleva, L S, Nazarov, K D, Anarbaev, R O, Petruseva, I O

“…Mammalian nucleotide excision repair (NER), known for its broad substrate specificity, is responsible for removal of bulky lesions from DNA. Over 30 proteins…”
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Photoactivated DNA analogs of substrates of the nucleotide excision repair system and their interaction with proteins of NER-competent HeLa cell extract by Petruseva, I. O, Tikhanovich, I. S, Maltseva, E. A, Safronov, I. V, Lavrik, O. I

“…Photoactivated DNA analogs of nucleotide excision repair (NER) substrates have been created that are 48-mer duplexes containing in internal positions…”
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Replication protein A modulates the activity of human telomerase in vitro by Rubtsova, M. P, Skvortsov, D. A, Petruseva, I. O, Lavrik, O. I, Spirin, P. V, Prasolov, V. S, Kisseljov, F. L, Dontsova, O. A

“…Our aim was to investigate how replication protein A (RPA) in a wide range of concentration can regulate the activity of human telomerase. We used an in vitro…”
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Genome Stability Maintenance in Naked Mole-Rat by Petruseva, I O, Evdokimov, A N, Lavrik, O I

“…The naked mole-rat ( ) is one of the most promising models used to study genome maintenance systems, including the effective repair of damage to DNA. The naked…”
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Molecular mechanism of global genome nucleotide excision repair by Petruseva, I O, Evdokimov, A N, Lavrik, O I

“…Nucleotide excision repair (NER) is a multistep process that recognizes and eliminates a wide spectrum of damage causing significant distortions in the DNA…”
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Comparative analysis of the primary structure and production of recombinant poly(ADP-ribose)polymerase 1 of long-lived Heterocephalus glaber by Naumenko, K. N., Nurislamov, A. R., Nazarov, K. D., Fishman, V. S., Popov, A. A., Petruseva, I. O., Evdokimov, A. N., Lavrik, O. I.

“…DNA repair is a most important cellular process that helps maintain the integrity of the genome and is currently considered by researchers as one of the…”
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Bulky Adducts in Clustered DNA Lesions: Causes of Resistance to the NER System by Naumenko, N V, Petruseva, I O, Lavrik, O I

“…The nucleotide excision repair (NER) system removes a wide range of bulky DNA lesions that cause significant distortions of the regular double helix structure…”
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A Method for Assessing the Efficiency of the Nucleotide Excision Repair System Ex Vivo by Popov, A A, Orishchenko, K E, Naumenko, K N, Evdokimov, A N, Petruseva, I O, Lavrik, O I

“…The nucleotide excision repair (NER) is one of the main repair systems present in the cells of living organisms. It is responsible for the removal of a wide…”
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DNA Bearing Bulky Fluorescent and Photoreactive Damage in Both Strands as Substrates of the Nucleotide Excision Repair System by Lukyanchikova, N. V., Petruseva, I. O., Evdokimov, A. N., Koroleva, L. S., Lavrik, O. I.

“…Model DNA molecules that contain bulky lesions in both strands have been created, and their properties as substrates of the nucleotide excision repair (NER)…”
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DNA with damage in both strands as affinity probes and nucleotide excision repair substrates by Lukyanchikova, N. V., Petruseva, I. O., Evdokimov, A. N., Silnikov, V. N., Lavrik, O. I.

“…Nucleotide excision repair (NER) is a multistep process of recognition and elimination of a wide spectrum of damages that cause significant distortions in DNA…”
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Unrepairable substrates of nucleotide excision repair and their application to suppress the activity of this repair system by Popov, A. A., Evdokimov, A. N., Lukyanchikova, N. V., Petruseva, I. O., Lavrik, O. I.

“…In the previous studies, the DNA with the bulky Fap-dC derivative was demonstrated to be a difficult substrate for the nucleotide excision repair (NER), a…”
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Interaction of nucleotide excision repair factors RPA and XPA with DNA containing bulky photoreactive groups imitating damages by Maltseva, E A, Rechkunova, N I, Petruseva, I O, Silnikov, V N, Vermeulen, W, Lavrik, O I

“…Interaction of nucleotide excision repair factors--replication protein A (RPA) and Xeroderma pigmentosum complementing group A protein (XPA)--with DNA…”
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Y-box binding protein 1 (YB-1) promotes detection of DNA bulky lesions by XPC-HR23B factor by Fomina, E. E., Pestryakov, P. E., Maltseva, E. A., Petruseva, I. O., Kretov, D. A., Ovchinnikov, L. P., Lavrik, O. I.

“…The nucleotide excision repair system (NER) is one of the main mechanisms protecting cellular DNA from lesions caused by such significant environmental factors…”
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DNA Bearing Bulky Fluorescent and Photoreactive Damage in Both Strands as Substrates of the Nucleotide Excision Repair System by Lukyanchikova, N V, Petruseva, I O, Evdokimov, A N, Koroleva, L S, Lavrik, O I

“…Model DNA molecules that contain bulky lesions in both strands have been created, and their properties as substrates of the nucleotide excision repair (NER)…”
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Unrepairable analogous of nucleotide excision repair substrates as a potential anti-cancer drugs by Evdokimov, A. N., Dolgova, E. V., Popov, A. A., Petruseva, I. O., Bogachev, S. S., Lavrik, O. I.

“…In the previous studies we have demonstrated that DNA with the bulky Fap-dC derivative is a hardly repairable substrate for the cellular NER system [1]. Such…”
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Influence of centrin 2 on the interaction of nucleotide excision repair factors with damaged DNA by Krasikova, Y. S., Rechkunova, N. I., Maltseva, E. A., Craescu, C. T., Petruseva, I. O., Lavrik, O. I.

“…We have examined the influence of centrin 2 (Cen2) on the interaction of nucleotide excision repair factors (XPC-HR23b, RPA, and XPA) with 48-mer DNA duplexes…”
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Model DNA for investigation of mechanism of nucleotide excision repair by Evdokimov, A. N., Lavrik, O. I., Petruseva, I. O.

“…The living cell DNA is under permanent attack of a variety of exogenous and endogenous damaging factors. Nucleotide excision repair (NER) is main pathway which…”
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Interaction of nucleotide excision repair factors XPC-HR23B, XPA, and RPA with damaged DNA by Krasikova, Yu. S., Rechkunova, N. I., Maltseva, E. A., Petruseva, I. O., Silnikov, V. N., Zatsepin, T. S., Oretskaya, T. S., Scharer, O. D., Lavrik, O. I.

“…The interaction of nucleotide excision repair factors-xeroderma pigmentosum complementation group C protein in complex with human homolog of yeast Rad23…”
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