Search Results - "Petrusca, Daniela N."

Structural and functional characterization of endothelial microparticles released by cigarette smoke by Serban, Karina A., Rezania, Samin, Petrusca, Daniela N., Poirier, Christophe, Cao, Danting, Justice, Matthew J., Patel, Milan, Tsvetkova, Irina, Kamocki, Krzysztof, Mikosz, Andrew, Schweitzer, Kelly S., Jacobson, Sean, Cardoso, Angelo, Carlesso, Nadia, Hubbard, Walter C., Kechris, Katerina, Dragnea, Bogdan, Berdyshev, Evgeny V., McClintock, Jeanette, Petrache, Irina

“…Circulating endothelial microparticles (EMPs) are emerging as biomarkers of chronic obstructive pulmonary disease (COPD) in individuals exposed to cigarette…”
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Osteocyte Vegf-a contributes to myeloma-associated angiogenesis and is regulated by Fgf23 by Mulcrone, Patrick L., Edwards, Shanique K. E., Petrusca, Daniela N., Haneline, Laura S., Delgado-Calle, Jesús, Roodman, G. David

“…Multiple Myeloma (MM) induces bone destruction, decreases bone formation, and increases marrow angiogenesis in patients. We reported that osteocytes (Ocys)…”
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Pharmacologic targeting of the p62 ZZ domain enhances both anti-tumor and bone-anabolic effects of bortezomib in multiple myeloma by Marino, Silvia, Petrusca, Daniela N, Bishop, Ryan T, Anderson, Judith L, Sabol, Hayley M, Ashby, Cody, Layer, Justin H, Cesarano, Annamaria, Davé, Utpal P, Perna, Fabiana, Delgado-Calle, Jesus, Chirgwin, John M, Roodman, G David

“…Multiple myeloma (MM) is a malignancy of plasma cells whose antibody secretion creates proteotoxic stress relieved by the N-end rule pathway, a proteolytic…”
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Increased S1P expression in osteoclasts enhances bone formation in an animal model of Paget's disease by Nagata, Yuki, Miyagawa, Kazuaki, Ohata, Yasuhisa, Petrusca, Daniela N., Pagnotti, Gabriel M., Mohammad, Khalid S., Guise, Theresa A., Windle, Jolene J., David Roodman, G., Kurihara, Noriyoshi

“…Paget's disease (PD) is characterized by increased numbers of abnormal osteoclasts (OCLs) that drive exuberant bone formation, but the mechanisms responsible…”
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Active trafficking of alpha 1 antitrypsin across the lung endothelium by Lockett, Angelia D, Brown, Mary Beth, Santos-Falcon, Nieves, Rush, Natalia I, Oueini, Houssam, Oberle, Amber J, Bolanis, Esther, Fragoso, Miryam A, Petrusca, Daniela N, Serban, Karina A, Schweitzer, Kelly S, Presson, Jr, Robert G, Campos, Michael, Petrache, Irina

“…The homeostatic lung protective effects of alpha-1 antitrypsin (A1AT) may require the transport of circulating proteinase inhibitor across an intact lung…”
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Alpha-1 antitrypsin supplementation improves alveolar macrophages efferocytosis and phagocytosis following cigarette smoke exposure by Serban, Karina A, Petrusca, Daniela N, Mikosz, Andrew, Poirier, Christophe, Lockett, Angelia D, Saint, Lauren, Justice, Matthew J, Twigg, 3rd, Homer L, Campos, Michael A, Petrache, Irina

“…Cigarette smoking (CS), the main risk factor for COPD (chronic obstructive pulmonary disease) in developed countries, decreases alveolar macrophages (AM)…”
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Effects of Lipid Interactions on Model Vesicle Engulfment by Alveolar Macrophages by Justice, Matthew J., Petrusca, Daniela N., Rogozea, Adriana L., Williams, Justin A., Schweitzer, Kelly S., Petrache, Irina, Wassall, Stephen R., Petrache, Horia I.

“…The engulfment function of macrophages relies on complex molecular interactions involving both lipids and proteins. In particular, the clearance of apoptotic…”
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Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis by Petrusca, Daniela N, Toscani, Denise, Wang, Feng-Ming, Park, Cheolkyu, Crean, Colin D, Anderson, Judith L, Marino, Silvia, Mohammad, Khalid S, Zhou, Dan, Silbermann, Rebecca, Sun, Quanhong, Kurihara, Noriyoshi, Galson, Deborah L, Giuliani, Nicola, Roodman, G David

“…In spite of major advances in treatment, multiple myeloma (MM) is currently an incurable malignancy due to the emergence of drug-resistant clones. We…”
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Therapeutic targets in myeloma bone disease by Marino, Silvia, Petrusca, Daniela N., Roodman, G. David

“…Multiple myeloma (MM) is the second most common haematological malignancy and is characterized by a clonal proliferation of neoplastic plasma cells within the…”
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Role of Sphingolipids in Multiple Myeloma Progression, Drug Resistance, and Their Potential as Therapeutic Targets by Petrusca, Daniela N., Lee, Kelvin P., Galson, Deborah L.

“…Multiple myeloma (MM) is an incapacitating hematological malignancy characterized by accumulation of cancerous plasma cells in the bone marrow (BM) and…”
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Smoking exposure induces human lung endothelial cell adaptation to apoptotic stress by Petrusca, Daniela N, Van Demark, Mary, Gu, Yuan, Justice, Matthew J, Rogozea, Adriana, Hubbard, Walter C, Petrache, Irina

“…Prolonged exposure to cigarette smoking is the main risk factor for emphysema, a component of chronic obstructive pulmonary diseases (COPDs) characterized by…”
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The involvement of sphingolipids in chronic obstructive pulmonary diseases by Petrache, Irina, Petrusca, Daniela N

“…Chronic obstructive pulmonary disease (COPD) includes a spectrum of conditions that have in common varying degrees of airflow obstruction, such as chronic…”
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Platelet hyperactivation, apoptosis and hypercoagulability in patients with acute pulmonary embolism by Rezania, Samin, Puskarich, Michael A, Petrusca, Daniela N, Neto-Neves, Evandro M, Rondina, Matthew T, Kline, Jeffrey A

“…Abstract Changes in systemic redox balance can alter platelet activation and aggregation. Acute pulmonary embolism (PE) is a systematic inflammatory disease…”
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Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS by Wu, Xue, Niculite, Cristina M., Preda, Mihai Bogdan, Rossi, Annalisa, Tebaldi, Toma, Butoi, Elena, White, Mattie K., Tudoran, Oana M., Petrusca, Daniela N., Jannasch, Amber S., Bone, William P., Zong, Xingyue, Fang, Fang, Burlacu, Alexandrina, Paulsen, Michelle T., Hancock, Brad A., Sandusky, George E., Mitra, Sumegha, Fishel, Melissa L., Buechlein, Aaron, Ivan, Cristina, Oikonomopoulos, Spyros, Gorospe, Myriam, Mosley, Amber, Radovich, Milan, Davé, Utpal P., Ragoussis, Jiannis, Nephew, Kenneth P., Mari, Bernard, McIntyre, Alan, Konig, Heiko, Ljungman, Mats, Cousminer, Diana L., Macchi, Paolo, Ivan, Mircea

“…We hereby provide the initial portrait of lincNORS , a spliced lincRNA generated by the MIR193BHG locus, entirely distinct from the previously described…”
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GFI1-Dependent Repression of SGPP1 Increases Multiple Myeloma Cell Survival by Petrusca, Daniela N, Mulcrone, Patrick L, Macar, David A, Bishop, Ryan T, Berdyshev, Evgeny, Suvannasankha, Attaya, Anderson, Judith L, Sun, Quanhong, Auron, Philip E, Galson, Deborah L, Roodman, G David

“…Multiple myeloma (MM) remains incurable for most patients due to the emergence of drug resistant clones. Here we report a p53-independent mechanism responsible…”
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Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells by Lockett, Angelia D, Petrusca, Daniela N, Justice, Matthew J, Poirier, Christophe, Serban, Karina A, Rush, Natalia I, Kamocka, Malgorzata, Predescu, Dan, Predescu, Sanda, Petrache, Irina

“…In addition to exerting a potent anti-elastase function, α-1 antitrypsin (A1AT) maintains the structural integrity of the lung by inhibiting endothelial…”
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Tissue transglutaminase protects epithelial ovarian cancer cells from cisplatin-induced apoptosis by promoting cell survival signaling by Cao, Liyun, Petrusca, Daniela N., Satpathy, Minati, Nakshatri, Harikrishna, Petrache, Irina, Matei, Daniela

“…Tissue transglutaminase (TG2), an enzyme involved in protein cross-linking and overexpressed in ovarian tumors, has antiapoptotic effects in cancer cells and…”
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Sphingolipid-mediated Inhibition of Apoptotic Cell Clearance by Alveolar Macrophages by Petrusca, Daniela N., Gu, Yuan, Adamowicz, Jeremy J., Rush, Natalia I., Hubbard, Walter C., Smith, Patricia A., Berdyshev, Evgeni V., Birukov, Konstantin G., Lee, Chao-Hung, Tuder, Rubin M., Twigg, Homer L., Vandivier, R. William, Petrache, Irina

“…A decreased clearance of apoptotic cells (efferocytosis) by alveolar macrophages (AM) may contribute to inflammation in emphysema. The up-regulation of…”
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Publisher Correction: Regulation of cellular sterol homeostasis by the oxygen responsive noncoding RNA lincNORS by Wu, Xue, Niculite, Cristina M., Preda, Mihai Bogdan, Rossi, Annalisa, Tebaldi, Toma, Butoi, Elena, White, Mattie K., Tudoran, Oana M., Petrusca, Daniela N., Jannasch, Amber S., Bone, William P., Zong, Xingyue, Fang, Fang, Burlacu, Alexandrina, Paulsen, Michelle T., Hancock, Brad A., Sandusky, George E., Mitra, Sumegha, Fishel, Melissa L., Buechlein, Aaron, Ivan, Cristina, Oikonomopoulos, Spyros, Gorospe, Myriam, Mosley, Amber, Radovich, Milan, Davé, Utpal P., Ragoussis, Jiannis, Nephew, Kenneth P., Mari, Bernard, McIntyre, Alan, Konig, Heiko, Ljungman, Mats, Cousminer, Diana L., Macchi, Paolo, Ivan, Mircea

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Impact of alginate-producing Pseudomonas aeruginosa on alveolar macrophage apoptotic cell clearance by McCaslin, Charles A, Petrusca, Daniela N, Poirier, Christophe, Serban, Karina A, Anderson, Gregory G, Petrache, Irina

“…Abstract Pseudomonas aeruginosa infection is a hallmark of lung disease in cystic fibrosis. Acute infection with P. aeruginosa profoundly inhibits alveolar…”
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