Search Results - "Petruk, K C"

Metabolic modulation of glioblastoma with dichloroacetate by Michelakis, E D, Sutendra, G, Dromparis, P, Webster, L, Haromy, A, Niven, E, Maguire, C, Gammer, T-L, Mackey, J R, Fulton, D, Abdulkarim, B, McMurtry, M S, Petruk, K C

“…Solid tumors, including the aggressive primary brain cancer glioblastoma multiforme, develop resistance to cell death, in part as a result of a switch from…”
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Nimodipine treatment in poor-grade aneurysm patients. Results of a multicenter double-blind placebo-controlled trial by Petruk, K C, West, M, Mohr, G, Weir, B K, Benoit, B G, Gentili, F, Disney, L B, Khan, M I, Grace, M, Holness, R O

“…A multicenter, randomized placebo-controlled double-blind trial of nimodipine in poor-grade aneurysm patients was carried out in 17 Canadian hospitals. Of 188…”
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Neuropsychological function in patients after subarachnoid hemorrhage by Bornstein, R A, Weir, B K, Petruk, K C, Disney, L B

“…Neuropsychological testing of 48 patients who had undergone operation for subarachnoid hemorrhage (SAH) due to aneurysm was performed. Before this, the…”
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Induction and intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) mediated apotosis in human malignant glioma cells by CHUNHAI HAO, BEGUINOT, Francesco, CONDORELLI, Gerolama, TRENCIA, Alessandra, VAN MEIR, Erwin G, YONG, V. Wee, PARNEY, Ian F, ROA, Wilson H, PETRUK, Kenneth C

“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) preferentially triggers apoptosis in tumor cells versus normal cells, thus providing a…”
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Improved technique for establishing short term human brain tumor cultures by FARR-JONES, M. A, PARNEY, I. F, PETRUK, K. C

“…Culturing human central nervous system tumors has been difficult compared to other neoplasms. We report improved success rates for establishing short term…”
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Howard H. Hepburn and the development of skull tongs for cervical spine traction by Parney, I F, Allen, P B, Petruk, K C

“…The first use of skull tongs for cervical spine traction is credited primarily to W.G. Crutchfield. In 1933, Crutchfield described his application of extension…”
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Glioma immunology and immunotherapy by Parney, I F, Hao, C, Petruk, K C

“…Despite advances in conventional therapy, the prognosis for most glioma patients remains dismal. This has prompted an intensive search for effective treatment…”
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Computed tomographic angiography versus digital subtraction angiography for the diagnosis and early treatment of ruptured intracranial aneurysms by Anderson, G B, Steinke, D E, Petruk, K C, Ashforth, R, Findlay, J M

“…Computed tomographic angiography (CTA) is a rapid and minimally invasive method of detecting intracranial aneurysms. We wished to determine whether CTA could…”
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Gene gun transfection of human glioma and melanoma cell lines with genes encoding human IL-12 and GM-CSF by GAINER, A. L, YOUNG, A. T. L, PARNEY, I. F, PETRUK, K. C, ELLIOTT, J. F

“…We used particle-mediated gene transfer by a custom-built gene gun to transfect two well-established human glioma (D54MG and U251) and melanoma (SK mel 28 and…”
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Effect of radiation on cytokine and cytokine receptor messenger-RNA profiles in p53 wild and mutated human glioblastoma cell lines by Yee, D, Hao, C, Cheung, H C, Chen, H T, Dabbagh, L, Hanson, J, Coupland, R, Petruk, K C, Fulton, D, Roa, W H

“…Glioblastoma cells produce cytokines with proinflammatory or immunosuppressive properties, or both, which, in addition to altered p53 gene expression, have…”
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Development of a large-animal human brain tumor xenograft model in immunosuppressed cats by KRUSHELNYCKY, B.W, FARR-JONES, M. A, MIELKE, B, MCKEAN, J. D, WEIR, B. K, PETRUK, K. C

“…A large-animal model was developed to facilitate the noninvasive investigation of the effect on the human glioma-derived D-54 MG (glioblastoma multiforme)…”
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Cerebrospinal fluid myelin basic protein as a prognostic marker in patients with head injury by Noseworthy, T W, Anderson, B J, Noseworthy, A F, Shustack, A, Johnston, R G, Petruk, K C, McPherson, T A

“…Despite increasing interest in identifying biochemical and serologic markers to judge the severity of closed head injury in comatose patients, clinical…”
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Anatomic details of intradural channels in the parasagittal dura: a possible pathway for flow of cerebrospinal fluid by Fox, R J, Walji, A H, Mielke, B, Petruk, K C, Aronyk, K E

“…The absorption of cerebrospinal fluid occurs primarily by means of arachnoid granulations (AG) in the superior sagittal sinus (SSS) and the lacunae laterales…”
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Decreased efficacy of levodopa with carbidopa in parkinsonian patients after adrenal-to-caudate implants by Tsui, J K, Peppard, R F, Petruk, K C, Allen, G, Burns, R S, Calne, D B

“…We studied 6 parkinsonian patients 6 weeks after unilateral adrenal-to-caudate implants. We withheld medications the night before each of 2 study days and gave…”
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Granulocyte-macrophage colony-stimulating factor and B7-2 combination immunogene therapy in an allogeneic Hu-PBL-SCID/beige mouse-human glioblastoma multiforme model by Parney, I F, Petruk, K C, Zhang, C, Farr-Jones, M, Sykes, D B, Chang, L J

“…Glioblastoma multiforme is the most common primary central nervous system neoplasm. Its dismal prognosis has led to investigation of new treatment strategies…”
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Human glioma immunobiology in vitro: implications for immunogene therapy by Parney, I F, Farr-Jones, M A, Chang, L J, Petruk, K C

“…Human gliomas are known to be immunosuppressive. Recent reports have suggested novel strategies to overcome this immunosuppression, including immunogene…”
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The effect of graded hypocapnia and hypercapnia on regional cerebral blood flow and cerebral vessel caliber in the rhesus monkey: study of cerebral hemodynamics following subarachnoid hemorrhage and traumatic internal carotid spasm by Petruk, K C, Weir, B K, Overton, T R, Marriott, M R, Grace, M G

“…Correlative cerebral blood flow (CBF) and vessel diameter studies were performed during graded Paco, change in control monkeys and in monkeys subjected to…”
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Acute hydrocephalus and eclampsia by Devitt, J H, Noseworthy, T W, Shustack, A, Hoskins, C F, Petruk, K C

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Cerebral blood flow following induced subarachnoid hemorrhage in the monkey by Petruk, K C, West, G R, Marriott, M R, McIntyre, J W, Overton, T R, Weib, B K

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An automatic bolus injector for use in radiotracer studies of blood flow: design and evaluation by Snyder, R E, Overton, T R, Boisvert, D P, Petruk, K C

“…An electromechanical device is described which automatically injects the radiotracer bolus used in the measurement of cerebral blood flow. It consists of two…”
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