Search Results - "Petropoulos, C. J."

Natural Variation of Drug Susceptibility in Wild-Type Human Immunodeficiency Virus Type 1 by Parkin, N T, Hellmann, N S, Whitcomb, J M, Kiss, L, Chappey, C, Petropoulos, C J

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Antiretroviral Resistance during Successful Therapy of HIV Type 1 Infection by Martinez-Picado, J., DePasquale, M. P., Kartsonis, N., Hanna, G. J., Wong, J., Finzi, D., Rosenberg, E., Gunthard, H. F., Sutton, L., Savara, A., Petropoulos, C. J., Hellmann, N., Walker, B. D., Richman, D. D., Siliciano, R., D'Aquila, R. T.

“…HIV type 1 (HIV-1) drug resistance mutations were selected during antiretroviral therapy successfully suppressing plasma HIV-1 RNA to <50 copies/ml. New…”
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A Novel Phenotypic Drug Susceptibility Assay for Human Immunodeficiency Virus Type 1 by Petropoulos, C J, Parkin, N T, Limoli, K L, Lie, Y S, Wrin, T, Huang, W, Tian, H, Smith, D, Winslow, G A, Capon, D J, Whitcomb, J M

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Sexual Transmission of an HIV-1 Variant Resistant to Multiple Reverse-Transcriptase and Protease Inhibitors by Hecht, Frederick M, Grant, Robert M, Petropoulos, Christos J, Dillon, Beth, Chesney, Margaret A, Tian, Huan, Hellmann, Nicholas S, Bandrapalli, Nirmala I, Digilio, Laura, Branson, Bernard, Kahn, James O

“…Combination treatments with agents that inhibit protease and reverse transcriptase of human immunodeficiency virus type 1 (HIV-1) decrease mortality and slow…”
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Drug Susceptibility in HIV Infection After Viral Rebound in Patients Receiving Indinavir-Containing Regimens by Havlir, Diane V, Hellmann, Nick S, Petropoulos, Christos J, Whitcomb, Jeannette M, Collier, Ann C, Hirsch, Martin S, Tebas, Pablo, Sommadossi, Jean-Pierre, Richman, Douglas D

“…CONTEXT Loss of viral suppression in patients infected with human immunodeficiency virus (HIV), who are receiving potent antiretroviral therapy, has been…”
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Reduced Antiretroviral Drug Susceptibility Among Patients With Primary HIV Infection by Little, Susan J, Daar, Eric S, D'Aquila, Richard T, Keiser, Philip H, Connick, Elizabeth, Whitcomb, Jeannette M, Hellmann, Nicholas S, Petropoulos, Christos J, Sutton, Lorraine, Pitt, Jacqui A, Rosenberg, Eric S, Koup, Richard A, Walker, Bruce D, Richman, Douglas D

“…CONTEXT The transmission of drug-resistant human immunodeficiency virus (HIV) has been documented, but the prevalence of such transmission is unknown…”
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Novel Four-Drug Salvage Treatment Regimens after Failure of a Human Immunodeficiency Virus Type 1 Protease Inhibitor-Containing Regimen: Antiviral Activity and Correlation of Baseline Phenotypic Drug Susceptibility with Virologic Outcome by Deeks, Steven G., Hellmann, Nicholas S., Grant, Robert M., Parkin, Neil T., Petropoulos, Christos J., Becker, Mark, Symonds, William, Chesney, Margaret, Volberding, Paul A.

“…Twenty human immunodeficiency virus—infected patients experiencing virologic failure of an indinavir- or ritonavir-containing treatment regimen were evaluated…”
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P04-47. High-titer autologous and heterologous neutralizing antibody activity in acute SIV-infection by Schweighardt, B, Ma, Z, Petropoulos, C J, Miller, C J, Wrin, T

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Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors by HUGHES, S. H, GREENHOUSE, J. J, PETROPOULOS, C. J, SUTRAVE, P

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Rapid Evolution of the Neutralizing Antibody Response to HIV Type 1 Infection by Richman, Douglas D., Wrin, Terri, Little, Susan J., Petropoulos, Christos J.

“…A recombinant virus assay was used to characterize in detail neutralizing antibody responses directed at circulating autologous HIV in plasma. Examining serial…”
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Replication-competent retrovirus vectors for the transfer and expression of gene cassettes in avian cells by Petropoulos, C.J. (NCI-Frederick Cancer Research and Development Center, Frederick, MD), Hughes, S.H

“…We have constructed a series of replication-competent retrovirus vectors to introduce and express gene cassettes in avian cells. To characterize these vectors,…”
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Cerebrospinal fluid response to structured treatment interruption after virological failure by PRICE, Richard W, PAXINOS, Ellen E, GRANT, Robert M, DREWS, Birgit, NILSSON, Annelie, HOH, Rebecca, HELLMANN, Nicholas S, PETROPOULOS, Christos J, DEEKS, Steven G

“…Structured antiretroviral treatment interruption (STI) has been advocated as a therapeutic strategy for HIV-1 infection. We report initial observations of…”
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Prevalence of Mutations Associated with Reduced Antiretroviral Drug Susceptibility among Human Immunodeficiency Virus Type 1 Seroconverters in the United States, 1993–1998 by Weinstock, Hillard, Respess, Richard, Heneine, Walid, Petropoulos, Christos J., Hellmann, Nicholas S., Luo, Chi-Cheng, Pau, Chou-Pong, Woods, Toni, Gwinn, Marta, Kaplan, Jonathan

“…To assess the prevalence of mutations associated with decreased antiretroviral drug susceptibility, specimens were tested from persons infected with human…”
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Comparative Analysis of Two Commercial Phenotypic Assays for Drug Susceptibility Testing of Human Immunodeficiency Virus Type 1 by QARI, Shoukat H, RESPESS, Richard, WEINSTOCK, Hillard, BELTRAMI, Elise M, HERTOGS, Kurt, LARDER, Brendan A, PETROPOULOS, Christos J, HELLMANN, Nicholas, HENEINE, Walid

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Baseline HIV Type 1 Coreceptor Tropism Predicts Disease Progression by Daar, Eric S., Kesler, Karen L., Petropoulos, Christos J., Huang, Wei, Bates, Michael, Lail, Alice E., Coakley, Eoin P., Gomperts, Edward D., Donfield, Sharyne M.

“…Background. Human immunodeficiency virus type 1 (HIV-1) coreceptor tropism, the ability of the virus to enter cells via CCR5 or CXCR4, is a viral…”
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Reduced Susceptibility of Human Immunodeficiency Virus Type 1 (HIV-1) from Patients with Primary HIV Infection to Nonnucleoside Reverse Transcriptase Inhibitors Is Associated with Variation at Novel Amino Acid Sites by Brown, A J, Precious, H M, Whitcomb, J M, Wong, J K, Quigg, M, Huang, W, Daar, E S, D'Aquila, R T, Keiser, P H, Connick, E, Hellmann, N S, Petropoulos, C J, Richman, D D, Little, S J

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Time Trends in Primary HIV-1 Drug Resistance Among Recently Infected Persons by Grant, Robert M, Hecht, Frederick M, Warmerdam, Maria, Liu, Lea, Liegler, Teri, Petropoulos, Christos J, Hellmann, Nicholas S, Chesney, Margaret, Busch, Michael P, Kahn, James O

“…CONTEXT Transmission of multiclass drug-resistant human immunodeficiency virus type 1 (HIV-1) may increase with wider use of antiretroviral therapy. OBJECTIVE…”
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Virologic and Immunologic Consequences of Discontinuing Combination Antiretroviral-Drug Therapy in HIV-Infected Patients with Detectable Viremia by Deeks, Steven G, Wrin, Terri, Liegler, Teri, Hoh, Rebecca, Hayden, Matthew, Barbour, Jason D, Hellmann, Nicholas S, Petropoulos, Christos J, McCune, Joseph M, Hellerstein, Marc K, Grant, Robert M

“…The goal of antiretroviral-drug therapy in patients with human immunodeficiency virus (HIV) infection is the complete suppression of viral replication. 1 , 2…”
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Phenotypic Changes in Drug Susceptibility Associated with Failure of Human Immunodeficiency Virus Type 1 (HIV-1) Triple Combination Therapy by Parkin, Neil T., Lie, Yolanda S., Hellmann, Nicholas, Markowitz, Martin, Bonhoeffer, Sebastian, Ho, David D., Petropoulos, Christos J.

“…The emergence of drug-resistant human immunodeficiency virus type 1 is a frequent cause of failure of combination therapies comprising reverse transcriptase…”
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Regulated transcription of c-Ki-ras and c-myc during compensatory growth of rat liver by Goyette, M, Petropoulos, C J, Shank, P R, Fausto, N

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