Search Results - "Petronek, M.S."

Utilization of redox modulating small molecules that selectively act as pro-oxidants in cancer cells to open a therapeutic window for improving cancer therapy by Petronek, M.S., Stolwijk, J.M., Murray, S.D., Steinbach, E.J., Zakharia, Y., Buettner, G.R., Spitz, D.R., Allen, B.G.

“…There is a rapidly growing body of literature supporting the notion that differential oxidative metabolism in cancer versus normal cells represents a metabolic…”
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Magnetite nanoparticles as a kinetically favorable source of iron to enhance GBM response to chemoradiosensitization with pharmacological ascorbate by Petronek, M.S., Teferi, N., Caster, J.M., Stolwijk, J.M., Zaher, A., Buatti, J.M., Hasan, D., Wafa, E.I., Salem, A.K., Gillan, E.G., St – Aubin, J.J., Buettner, G.R., Spitz, D.R., Magnotta, V.A., Allen, B.G.

“…Ferumoxytol (FMX) is an FDA-approved magnetite (Fe3O4) nanoparticle used to treat iron deficiency anemia that can also be used as an MR imaging agent in…”
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Avasopasem manganese (GC4419) protects against cisplatin-induced chronic kidney disease: An exploratory analysis of renal metrics from a randomized phase 2b clinical trial in head and neck cancer patients by Mapuskar, K.A., Vasquez Martinez, G., Pulliam, C.F., Petronek, M.S., Steinbach, E.J., Monga, V., Furqan, M., Jetton, J.G., Saunders, D.P., Pearce, A., Davidson, S., Pitre, L., Dunlap, N.E., Fairbanks, R., Lee, C.M., Mott, S.L., Bodeker, K.L., Cl, Huang, Buatti, J.M., Anderson, C.M., Beardsley, R.A., Holmlund, J.T., Zepeda-Orozco, D., Spitz, D.R., Allen, B.G.

“…Head and neck squamous cell carcinoma (HNSCC) patients treated with high-dose cisplatin concurrently with radiotherapy (hdCis-RT) commonly suffer kidney injury…”
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Utilizing Pharmacologic Ascorbate to Enhance the Therapeutic Index of DNA Repair Inhibitor-Based Chemoradiotherapy for Rectal Cancers by Callaghan, C.M., Seyedin, S.N., Mapuskar, K.A., Petronek, M.S., Hasibuzzaman, M.M., Cullen, J.J., Spitz, D.R., Allen, B.G., Caster, J.M.

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Pharmacologic Ascorbate Enhances the Therapeutic Index of ATM-Inhibitor Based Chemoradiation for Colorectal Cancer by Callaghan, C.M., Abukhiran, I., VanRheeden, R., Ali, M.Y., Petronek, M.S., Mapuskar, K.A., Seyedin, S.N., Kalen, A.L., Rodman, S., Cullen, J.J., Coleman, M., Goswami, P., Buatti, J., Spitz, D.R., Allen, B.G., Caster, J.M.

“…Ataxia telangiectasia mutated protein (ATM) is one of the key sensors of DNA damage and specific inhibitors of ATM are potent radiosensitizers. However, their…”
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