Search Results - "Petrillo, Nadia"
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Predictive significance of FGFR4 p.G388R polymorphism in metastatic colorectal cancer patients receiving trifluridine/tipiracil (TAS-102) treatment
Published in Journal of translational medicine (22-04-2024)“…TAS-102 (Lonsurf ) is an oral fluoropyrimidine consisting of a combination of trifluridine (a thymidine analog) and tipiracil (a thymidine phosphorylation…”
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BRAF p.V600E mutation as a molecular boundary between genuine oligo-repeated and poly-metastatic disease in colorectal cancer
Published in Neoplasia (New York, N.Y.) (01-10-2023)Get full text
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Characterization of KRAS Mutational Regression in Oligometastatic Patients
Published in Frontiers in immunology (22-07-2022)“…Background We previously reported rare regressive genetic trajectories of KRAS pathogenic mutations as a specific hallmark of the genuine oligometastatic…”
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Non-invasive prenatal testing can detect silent cancers in expecting mothers
Published in Genes & diseases (01-03-2024)Get full text
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Clinical and Molecular Characteristics of Rare Malignant Tumors of Colon and Rectum
Published in Biology (Basel, Switzerland) (08-02-2022)“…The most frequent form of colorectal cancer is represented by adenocarcinoma being about 98% of tumor histological types. However, other rare histotypes can be…”
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Innovative Drug Modalities for the Treatment of Advanced Prostate Cancer
Published in Diseases (01-05-2024)“…Prostate cancer, a prevalent malignancy affecting the prostate gland, is a significant global health concern. Androgen-deprivation therapy (ADT) has proven…”
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Hypertension, type 2 diabetes, obesity, and p53 mutations negatively correlate with metastatic colorectal cancer patients' survival
Published in Frontiers in medicine (23-01-2023)“…We studied the predictive and prognostic influences of hypertension (HT), type 2 diabetes (T2D), weight, and mutations in metastatic colorectal cancer (CRC)…”
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Genetic landscape of colorectal cancer patients manifesting tumor shrinkage during SARS-Cov-2 infection
Published in Therapeutic advances in medical oncology (01-01-2022)“…We previously described three patients affected by metastatic colorectal cancer (mCRC) who experienced spontaneous tumour shrinkage during severe acute…”
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Non-Invasive Prenatal Screening: The First Report of Pentasomy X Detected by Plasma Cell-Free DNA and Karyotype Analysis
Published in Diagnostics (Basel) (01-07-2022)“…Pentasomy X is a sex chromosome anomaly caused by the presence of three extra X chromosomes in females (49,XXXXX instead of 46,XX) and is probably due to a…”
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The prognostic role of p53 mutations in metastatic colorectal cancer: A systematic review and meta-analysis
Published in Critical reviews in oncology/hematology (01-06-2023)“…P53 is one of the most frequently mutated genes in colorectal cancer (CRC). The present study was undertaken to provide a solid estimate of the prognostic…”
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KRAS p.G12C Mutation in Metastatic Colorectal Cancer: Prognostic Implications and Advancements in Targeted Therapies
Published in Cancers (12-07-2023)“…is frequently mutated in tumors. It is mutated in approximately 30% of all cancer cases and in nearly 50% of cases of metastatic colorectal cancer (CRC), which…”
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Oligo-Metastatic Disease in Oncology: Exploring the Limits and the Potential of Genetic Assessment
Published in Genes (26-11-2023)“…Oligo-metastatic disease (OMD) in the field of oncology denotes a distinct subset of metastatic tumors characterized by less aggressive biological behavior and…”
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Non-invasive prenatal test identifies circulating cell-free DNA chromosomal abnormalities derived from clonal hematopoiesis in aggressive hematological malignancies
Published in Clinical and experimental medicine (05-04-2024)“…Liquid biopsy is a minimally invasive diagnostic tool for identification of tumor-related mutations in circulating cell-free DNA (cfDNA). The aim of this study…”
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IKRAS/I p.G12C Mutation in Metastatic Colorectal Cancer: Prognostic Implications and Advancements in Targeted Therapies
Published in Cancers (01-07-2023)“…In this review, we aim to clarify the prognostic significance of the KRAS p.G12C mutation in metastatic colorectal cancer, emphasizing its potential as a…”
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A Case Report of a Feto-Placental Mosaicism Involving a Segmental Aneuploidy: A Challenge for Genome Wide Screening by Non-Invasive Prenatal Testing of Cell-Free DNA in Maternal Plasma
Published in Genes (01-03-2023)“…Non-invasive prenatal testing (NIPT) using cell-free DNA can detect fetal chromosomal anomalies with high clinical sensitivity and specificity. In…”
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Clinical Experience with Genome-Wide Noninvasive Prenatal Screening in a Large Cohort of Twin Pregnancies
Published in Genes (26-04-2023)“…Non-invasive prenatal screening (NIPS) in twin gestations has been shown to have high detection rates and low false-positive rates for trisomy 21, as seen in…”
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A Case Report of a Feto-Placental Mosaicism Involving a Segmental Aneuploidy: A Challenge for Genome Wide Screening by Non-Invasive Prenatal Testing of Cell-Free DNA in Maternal Plasma
Published in Genes (07-03-2023)“…Non-invasive prenatal testing (NIPT) using cell-free DNA can detect fetal chromosomal anomalies with high clinical sensitivity and specificity. In…”
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