Search Results - "Petrie, Whitney K"

G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth by Petrie, Whitney K., Dennis, Megan K., Hu, Chelin, Dai, Donghai D., Arterburn, Jeffrey B., Smith, Harriet O., Hathaway, Helen J., Prossnitz, Eric R.

“…Endometrial carcinoma is the most common cancer of the female reproductive tract. GPER/GPR30 is a 7-transmembrane spanning G protein-coupled receptor that has…”
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Diet-induced metabolic change induces estrogen-independent allometric mammary growth by Berryhill, Grace E, Gloviczki, Julia M, Trott, Josephine F, Aimo, Lucila, Kraft, Jana, Cardiff, Robert D, Paul, Carly T, Petrie, Whitney K, Lock, Adam L, Hovey, Russell C

“…Lifetime breast cancer risk reflects an unresolved combination of early life factors including diet, body mass index, metabolic syndrome, obesity, and age at…”
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In vivo effects of a GPR30 antagonist by Dennis, Megan K, Burai, Ritwik, Ramesh, Chinnasamy, Petrie, Whitney K, Alcon, Sara N, Nayak, Tapan K, Bologa, Cristian G, Leitao, Andrei, Brailoiu, Eugen, Deliu, Elena, Dun, Nae J, Sklar, Larry A, Hathaway, Helen J, Arterburn, Jeffrey B, Oprea, Tudor I, Prossnitz, Eric R

“…Estrogen is central to many physiological processes throughout the human body. We have previously shown that the G protein–coupled receptor GPR30 (also known…”
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Identification of a GPER/GPR30 antagonist with improved estrogen receptor counterselectivity by Dennis, Megan K., Field, Angela S., Burai, Ritwik, Ramesh, Chinnasamy, Petrie, Whitney K., Bologa, Cristian G., Oprea, Tudor I., Yamaguchi, Yuri, Hayashi, Shin-Ichi, Sklar, Larry A., Hathaway, Helen J., Arterburn, Jeffrey B., Prossnitz, Eric R.

“…► We identify a GPER antagonist G36 with increased selectivity against ERα/β. ► G36 exhibits reduced ER binding/activation compared to G15. ► G36 inhibits GPER…”
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Differential Downregulation of E-Cadherin and Desmoglein by Epidermal Growth Factor by Chavez, Miquella G., Buhr, Christian A., Petrie, Whitney K., Wandinger-Ness, Angela, Kusewitt, Donna F., Hudson, Laurie G.

“…Modulation of cell : cell junctions is a key event in cutaneous wound repair. In this study we report that activation of the epidermal growth factor (EGF)…”
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A Selective Ligand for Estrogen Receptor Proteins Discriminates Rapid and Genomic Signaling by Revankar, Chetana M, Bologa, Cristian G, Pepermans, Richard A, Sharma, Geetanjali, Petrie, Whitney K, Alcon, Sara N, Field, Angela S, Ramesh, Chinnasamy, Parker, Matthew A, Savchuk, Nikolay P, Sklar, Larry A, Hathaway, Helen J, Arterburn, Jeffrey B, Oprea, Tudor I, Prossnitz, Eric R

“…Estrogen exerts extensive and diverse effects throughout the body of women. In addition to the classical nuclear estrogen receptors (ERα and ERβ), the G…”
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A local basis for progesterone action during mammary tumorigenesis - no longer RANK and file by Petrie, Whitney K, Hovey, Russell C

“…Two recent reports provide compelling insights into the role for RANK and its ligand, RANKL, in progestin-dependent mammary tumorigenesis. These findings build…”
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Diet-induced metabolic change induces estrogen-independent allometric mammary growth by Berryhill, Grace E, Gloviczki, Julia M, Trott, Josephine F, Aimo, Lucila, Kraft, Jana, Cardiff, Robert D, Paul, Carly T, Petrie, Whitney K, Lock, Adam L, Hovey, Russell C

“…Lifetime breast cancer risk reflects an unresolved combination of early life factors including diet, body mass index, metabolic syndrome, obesity, and age at…”
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Characterization of the estrogen receptor GPR30 in human endometrial cancer cells and the mouse uterus by Petrie, Whitney K

“…GPR30, a seven transmembrane G protein-coupled receptor, has recently been described as a novel estrogen receptor that promotes multiple cellular and…”
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