Search Results - "Petrie, N."
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Pharmacokinetics and central accumulation of delta-9-tetrahydrocannabinol (THC) and its bioactive metabolites are influenced by route of administration and sex in rats
Published in Scientific reports (14-12-2021)“…Up to a third of North Americans report using cannabis in the prior month, most commonly through inhalation. Animal models that reflect human consumption are…”
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Myenteric expression of nerve growth factor and the p75 neurotrophin receptor regulate axonal remodeling as a consequence of colonic inflammation in mice
Published in Experimental neurology (01-09-2015)“…Nerve growth factor (NGF) levels increase in response to inflammation of the mammalian colon. The precise cellular sources of colonic NGF synthesis, however,…”
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3
Response to “Seat belt injury causing bisection of the breast: A case report”
Published in Journal of plastic, reconstructive & aesthetic surgery (01-03-2015)Get full text
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4
A genetic variant of fatty acid amide hydrolase (FAAH) exacerbates hormone-mediated orexigenic feeding in mice
Published in eLife (11-04-2023)“…Fatty acid amide hydrolase (FAAH) degrades the endocannabinoid anandamide. A polymorphism in (FAAH C385A) reduces FAAH expression, increases anandamide levels,…”
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Improving medication safety for home nursing clients: A prospective observational study of a novel clinical pharmacy service—The Visiting Pharmacist (ViP) study
Published in Journal of clinical pharmacy and therapeutics (01-12-2018)“…Summary What is known and objective Polypharmacy, medication errors and adverse events are common in older people receiving home nursing medication management…”
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Sex and stressor modality influence acute stress-induced dynamic changes in corticolimbic endocannabinoid levels in adult Sprague Dawley rats
Published in Neurobiology of stress (01-09-2022)“…Research over the past few decades has established a role for the endocannabinoid system in contributing to the neural and endocrine responses to stress…”
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N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice
Published in Neuropharmacology (01-04-2019)“…Cigarette smokers with brain damage involving the insular cortex display cessation of tobacco smoking, suggesting that this region may contribute to nicotine…”
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Acute stress activates basolateral amygdala neurons expressing corticotropin-releasing hormone receptor type 1 (CRHR1): Topographical distribution and projection-specific activation in male and female rats
Published in Neurobiology of stress (01-11-2024)“…Although the basolateral amygdala (BLA) and corticotropin releasing hormone receptor type I (CRHR1) signaling are both central to the stress response, the…”
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Endocannabinoids, cannabinoids and the regulation of anxiety
Published in Neuropharmacology (01-09-2021)“…Cannabis has been used for hundreds of years, with its ability to dampen feelings of anxiety often reported as a primary reason for use. Only recently has the…”
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Endocannabinoids: Effectors of glucocorticoid signaling
Published in Frontiers in neuroendocrinology (01-10-2017)“…•Glucocorticoids and endocannabinoids regulate many behaviours in an analogous way.•Glucocorticoid signaling is known to mobilize the endocannabinoid…”
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PRM37 Indirect Identification of Payer Perceptions Through Retrospective Analysis of Interview Write-Ups
Published in Value in health (01-11-2012)Get full text
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PHP106 Impact of Payer Perceptions of Pharma Companies on Access Decisions - an Analysis of Unprompted Expressions in Payer Interviews
Published in Value in health (01-11-2012)Get full text
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13
Vaporized Cannabis Extracts Have Reinforcing Properties and Support Conditioned Drug-Seeking Behavior in Rats
Published in The Journal of neuroscience (26-02-2020)“…Recent trends in cannabis legalization have increased the necessity to better understand the effects of cannabis use. Animal models involving traditional…”
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Identification of a stress-responsive subregion of the basolateral amygdala in male rats
Published in Neuropsychopharmacology (New York, N.Y.) (01-12-2024)“…The basolateral amygdala (BLA) is reliably activated by psychological stress and hyperactive in conditions of pathological stress or trauma; however, subsets…”
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Disruption of tonic endocannabinoid signalling triggers cellular, behavioural and neuroendocrine responses consistent with a stress response
Published in British journal of pharmacology (01-12-2023)“…Background and Purpose Endocannabinoid (eCB) signalling gates many aspects of the stress response, including the hypothalamic–pituitary–adrenal (HPA) axis. The…”
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Maternal‐fetal transmission of delta‐9‐tetrahydrocannabinol (THC) and its metabolites following inhalation and injection exposure during pregnancy in rats
Published in Journal of neuroscience research (01-03-2022)“…Cannabis use during pregnancy has increased over the past few decades, with recent data indicating that, in youth and young adults especially, up to 22% of…”
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Suppression of acute and anticipatory nausea by peripherally restricted fatty acid amide hydrolase inhibitor in animal models: role of PPARα and CB1 receptors
Published in British journal of pharmacology (01-11-2017)“…Background and Purpose Effective treatments of nausea are limited. In this study we evaluated the ability of the peripherally restricted fatty acid amide…”
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Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague–Dawley rats
Published in Psychopharmacology (01-09-2019)“…Rationale Oleoyl glycine (OlGly), a recently discovered fatty acid amide that is structurally similar to N- acylethanolamines, which include the…”
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Role of the stress response and the endocannabinoid system in Δ9-tetrahydrocannabinol (THC)-induced nausea
Published in Psychopharmacology (01-07-2020)“…Rationale Dysregulation of the endocannabinoid (eCB) system by high doses of Δ 9 -tetrahydrocannabinol (THC) is hypothesized to generate a dysfunctional…”
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Double Dissociation of Monoacylglycerol Lipase Inhibition and CB1 Antagonism in the Central Amygdala, Basolateral Amygdala, and the Interoceptive Insular Cortex on the Affective Properties of Acute Naloxone-Precipitated Morphine Withdrawal in Rats
Published in Neuropsychopharmacology (New York, N.Y.) (01-06-2016)“…Both CB1 receptor antagonism and agonism, in particular by 2-arachidonyl glycerol (2-AG), have been shown to reduce somatic symptoms of morphine withdrawal…”
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