Search Results - "Petrie, John L"

Fructose 2,6-bisphosphate is essential for glucose-regulated gene transcription of glucose-6-phosphatase and other ChREBP target genes in hepatocytes by Arden, Catherine, Tudhope, Susan J, Petrie, John L, Al-Oanzi, Ziad H, Cullen, Kirsty S, Lange, Alex J, Towle, Howard C, Agius, Loranne

“…Glucose metabolism in the liver activates the transcription of various genes encoding enzymes of glycolysis and lipogenesis and also G6pc…”
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Real-World Persistence with Ocrelizumab in Multiple Sclerosis: a Systematic Review by Petrie, John L., Smith, Charlie A., Fountain, Donna, Machnicki, Gerardo

“…In clinical trials, the percentage of patients discontinuing treatment with ocrelizumab due to adverse events was low. However, real-world populations are…”
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Real‐world evaluation of ocrelizumab in multiple sclerosis: A systematic review by Montalban, Xavier, Matthews, Paul M., Simpson, Alex, Petrie, John L., Sammon, Cormac, Ramagopalan, Sreeram, Disanto, Giulio, Kuhle, Jens

“…Across its clinical development program, ocrelizumab demonstrated efficacy in improving clinical outcomes in multiple sclerosis, including annualized relapse…”
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Elevated Glucose Represses Liver Glucokinase and Induces Its Regulatory Protein to Safeguard Hepatic Phosphate Homeostasis by ARDEN, Catherine, PETRIE, John L, TUDHOPE, Susan J, AL-OANZI, Ziad, CLAYDON, Amy J, BEYNON, Robert J, TOWLE, Howard C, AGIUS, Loranne

“…The induction of hepatic glucose 6-phosphatase (G6pc) by glucose presents a paradox of glucose-induced glucose intolerance. We tested whether glucose…”
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The rate of production of uric acid by hepatocytes is a sensitive index of compromised cell ATP homeostasis by Petrie, John L, Patman, Gillian L, Sinha, Ishita, Alexander, Thomas D, Reeves, Helen L, Agius, Loranne

“…Plasma levels of uric acid, the final product of purine degradation in humans, are elevated in metabolic syndrome and are strongly associated with insulin…”
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Glucose Induces Protein Targeting to Glycogen in Hepatocytes by Fructose 2,6-Bisphosphate-Mediated Recruitment of MondoA to the Promoter by Petrie, John L., Al-Oanzi, Ziad H., Arden, Catherine, Tudhope, Susan J., Mann, Jelena, Kieswich, Julius, Yaqoob, Muhammad M., Towle, Howard C., Agius, Loranne

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Novel Mechanism for Regulating Hepatic Glycogen Synthesis Involving Serotonin and Cyclin-Dependent Kinase-5 by TUDHOPE, Susan J, WANG, Chung-Chi, PETRIE, John L, POTTS, Lloyd, MALCOMSON, Fiona, KIESWICH, Julius, YAQOOB, Muhammad M, ARDEN, Catherine, HAMPSON, Laura J, AGIUS, Loranne

“…Hepatic autonomic nerves regulate postprandial hepatic glucose uptake, but the signaling pathways remain unknown. We tested the hypothesis that serotonin…”
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Effects on prostate cancer cells of targeting RNA polymerase III by Petrie, John L, Swan, Caroline, Ingram, Richard M, Frame, Fiona M, Collins, Anne T, Dumay-Odelot, Hélène, Teichmann, Martin, Maitland, Norman J, White, Robert J

“…Abstract RNA polymerase (pol) III occurs in two forms, containing either the POLR3G subunit or the related paralogue POLR3GL. Whereas POLR3GL is ubiquitous,…”
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Induction of proto-oncogene BRF2 in breast cancer cells by the dietary soybean isoflavone daidzein by Koo, Jana, Cabarcas-Petroski, Stephanie, Petrie, John L, Diette, Nicole, White, Robert J, Schramm, Laura

“…BRF2 is a transcription factor required for synthesis of a small group of non-coding RNAs by RNA polymerase III. Overexpression of BRF2 can transform human…”
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Opposite effects of a glucokinase activator and metformin on glucose‐regulated gene expression in hepatocytes by Al‐Oanzi, Ziad H., Fountana, Sophia, Moonira, Tabassum, Tudhope, Susan J., Petrie, John L., Alshawi, Ahmed, Patman, Gillian, Arden, Catherine, Reeves, Helen L., Agius, Loranne

“…Aim Small molecule activators of glucokinase (GKAs) have been explored extensively as potential anti‐hyperglycaemic drugs for type 2 diabetes (T2D). Several…”
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The putative tumour suppressor protein Latexin is secreted by prostate luminal cells and is downregulated in malignancy by Seed, Robert I., Taurozzi, Alberto J., Wilcock, Daniel J., Nappo, Giovanna, Erb, Holger H. H., Read, Martin L., Gurney, Mark, Archer, Leanne K., Ito, Saburo, Rumsby, Martin G., Petrie, John L., Clayton, Aled, Maitland, Norman J., Collins, Anne T.

“…Loss of latexin (LXN) expression negatively correlates with the prognosis of several human cancers. Despite association with numerous processes including…”
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