Search Results - "Petray, Patricia"

Importance of CD40/CD40 dyad in the course of infection with Trypanosoma cruzi: Impact of its inhibition by Frank, Fernanda M., Wagner, David H., Postan, Miriam, Petray, Patricia B.

“…Chagas heart disease (CHD), caused by the protozoan parasite Trypanosoma cruzi, consists of a progressive myocarditis which may lead to congestive heart…”
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Imiquimod-loaded nanoarchaeosomes as a promising immunotherapy against Trypanosoma cruzi infection by Parra, Federico L., Frank, Fernanda M., Alliani, Bruno F., Romero, Eder L., Petray, Patricia B.

“…[Display omitted] •NanoARC-IMQ were prepared following a simple and scalable protocol.•The efficacy of nanoARC-IMQ to induce protection against T. cruzi was…”
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MIF-driven activation of macrophages induces killing of intracellular Trypanosoma cruzi dependent on endogenous production of tumor necrosis factor, nitric oxide and reactive oxygen species by Cutrullis, Romina A, Petray, Patricia B, Corral, Ricardo S

“…Abstract The proinflammatory cytokine macrophage migration inhibitory factor (MIF) is a key player in innate immunity. MIF has been considered critical for…”
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Germacranolide-type sesquiterpene lactones from Smallanthus sonchifolius with promising activity against Leishmania mexicana and Trypanosoma cruzi by Ulloa, Jerónimo L, Spina, Renata, Casasco, Agustina, Petray, Patricia B, Martino, Virginia, Sosa, Miguel A, Frank, Fernanda M, Muschietti, Liliana V

“…Leishmaniasis and Chagas disease are life-threatening illnesses caused by the protozoan parasites Leishmania spp. and Trypanosoma cruzi, respectively. They are…”
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Circulating T Follicular Helper Cell Abnormalities Associated to Different Clinical Forms of Chronic Chagas Disease by Quebrada Palacio, Luz P, Fernández, Esteban R, Hernández-Vásquez, Yolanda, Petray, Patricia B, Postan, Miriam

“…Multiple perturbations of the immune response affecting a range of cells have been reported in -infected individuals and associated to clinical manifestations…”
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Elevated serum levels of macrophage migration inhibitory factor are associated with progressive chronic cardiomyopathy in patients with Chagas disease by Cutrullis, Romina A, Petray, Patricia B, Schapachnik, Edgardo, Sánchez, Rubén, Postan, Miriam, González, Mariela N, Martín, Valentina, Corral, Ricardo S

“…Clinical symptoms of chronic Chagas disease occur in around 30% of the individuals infected with Trypanosoma cruzi and are characterized by heart inflammation…”
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Trypanosoma cruzi infection induces the expression of CD40 in murine cardiomyocytes favoring CD40 ligation-dependent production of cardiopathogenic IL-6 by Moreno Ayala, Mariela Alejandra, Casasco, Agustina, González, Mariela, Postan, Miriam, Corral, Ricardo Santiago, Petray, Patricia Beatriz

“…The inflammatory response in the myocardium is an important aspect of the pathogenesis of Chagas’ heart disease raised by Trypanosoma cruzi. CD40, a…”
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Benznidazole Therapy Modulates Interferon-γ and M2 Muscarinic Receptor Autoantibody Responses in Trypanosoma cruzi-Infected Children by Cutrullis, Romina A., Moscatelli, Guillermo F., Moroni, Samanta, Volta, Bibiana J., Cardoni, Rita L., Altcheh, Jaime M., Corral, Ricardo S., Freilij, Héctor L., Petray, Patricia B.

“…Objective The presence of autoantibodies with adrenergic and cholinergic activity, capable of triggering neurotransmitter receptor-mediated effects, has been…”
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Archaeosomes made of Halorubrum tebenquichense total polar lipids: a new source of adjuvancy by Gonzalez, Raul O, Higa, Leticia H, Cutrullis, Romina A, Bilen, Marcos, Morelli, Irma, Roncaglia, Diana I, Corral, Ricardo S, Morilla, Maria Jose, Petray, Patricia B, Romero, Eder L

“…Archaeosomes (ARC), vesicles prepared from total polar lipids (TPL) extracted from selected genera and species from the Archaea domain, elicit both antibody…”
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Archaeosomes display immunoadjuvant potential for a vaccine against Chagas disease by Higa, Leticia H, Corral, Ricardo S, Morilla, María José, Romero, Eder L, Petray, Patricia B

“…Archaeosomes (ARC), vesicles made from lipids extracted from Archaea, display strong adjuvant properties. In this study, we evaluated the ability of the highly…”
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Immunomodulatory and anti-fibrotic effects of ganglioside therapy on the cardiac chronic form of experimental Trypanosoma cruzi infection by Cutrullis, Romina Andrea, Poklépovich, Tomás Javier, Postan, Miriam, Freilij, Héctor Leon, Petray, Patricia Beatriz

“…Heart failure and sudden death are the most common causes of death in patients with Chagas' disease. The main drug available for Chagas treatment is…”
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Timing of expression of inflammatory mediators in skeletal muscles from mice acutely infected with the RA strain of Trypanosoma cruzi by Cutrullis, Romina Andrea, Postan, Miriam, Petray, Patricia Beatriz, Corral, Ricardo Santiago

“…Chagas' disease is caused by persistent Trypanosoma cruzi infection in muscle cells that ultimately results in chronic inflammation and tissue destruction. The…”
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Use of a purified Trypanosoma cruzi antigen and CpG oligodeoxynucleotides for immunoprotection against a lethal challenge with trypomastigotes by Frank, Fernanda M., Petray, Patricia B., Cazorla, Silvia I., Muñoz, Marina C., Corral, Ricardo S., Malchiodi, Emilio L.

“…The crucial role played by Ag163B6/cruzipain, the major cystein proteinase of Trypanosoma cruzi, in the process of parasite internalization into mammalian…”
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CpG DNA as a Th1-promoting adjuvant in immunization against Trypanosoma cruzi by Corral, Ricardo S., Petray, Patricia B.

“…Th1-type immune response plays a critical role in resistance to Trypanosoma cruzi infection. We asked whether a synthetic oligodeoxynucleotide that contains…”
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In vitro activity of Etanidazole against the protozoan parasite Trypanosoma cruzi by Petray, Patricia B, Morilla, María J, Corral, Ricardo S, Romero, Eder L

“…We investigated the in vitro action of an hydrosoluble 2-nitroimidazole, Etanidazole (EZL), against Trypanosoma cruzi, the etiologic agent of Chagas disease…”
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Importance of CD40/CD40L dyad in the course of infection with Trypanosoma cruzi: Impact of its inhibition by Frank, Fernanda M., Wagner, David H., Postan, Miriam, Petray, Patricia B.

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Anti-M2 muscarinic receptor autoantibodies in Trypanosoma cruzi-infected pediatric patients treated with benznidazole by Cutrullis, Romina, Ballering, Griselda, Altcheh, Jaime, Moscatelli, Guillermo Moscatelli, Corral, Ricardo Corral, Petray, Patricia Petray, Freilij, Héctor

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Molecular and functional characterization of two malic enzymes from Leishmania parasites by Giordana, Lucila, Sosa, Máximo Hernán, Leroux, Alejandro E., Mendoza, Elkin F. Rodas, Petray, Patricia, Nowicki, Cristina

“…[Display omitted] •The two isoforms of leishmanial malic enzyme exhibit an identity of about 55%.•Only one of the two isozymes is allosterically activated by…”
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Benzonidazole therapy modulates interferon-γ and M2 muscarinic receptor autoantibody responses in Trypanosoma cruzi-infected children by Cutrullis, Romina A, Moscatelli, Guillermo F, Moroni, Samanta, Volta, Bibiana J, Cardoni, Rita L, Altcheh, Jaime M, Corral, Ricardo S, Freilij, Héctor L, Petray, Patricia B

“…The presence of autoantibodies with adrenergic and cholinergic activity, capable of triggering neurotransmitter receptor-mediated effects, has been associated…”
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Enhanced photodynamic leishmanicidal activity of hydrophobic zinc phthalocyanine within archaeolipids containing liposomes by Perez, Ana Paula, Casasco, Agustina, Schilrreff, Priscila, Tesoriero, Maria Victoria Defain, Duempelmann, Luc, Pappalardo, Juan Sebastián, Altube, Maria Julia, Higa, Leticia, Morilla, Maria Jose, Petray, Patricia, Romero, Eder L

“…In this work, the in vitro anti-Leishmania activity of photodynamic liposomes made of soybean phosphatidylcholine, sodium cholate, total polar archaeolipids…”
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