Search Results - "Petrashevskaya, N."

β1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure by Perez, Jeanne Mialet, Rathz, Deborah A, Petrashevskaya, Natalia N, Hahn, Harvey S, Wagoner, Lynne E, Schwartz, Arnold, Dorn, II, Gerald W, Liggett, Stephen B

Get full text

Ablation of sarcolipin enhances sarcoplasmic reticulum calcium transport and atrial contractility by Babu, Gopal J, Bhupathy, Poornima, Timofeyev, Valeriy, Petrashevskaya, Natalia N, Reiser, Peter J, Chiamvimonvat, Nipavan, Periasamy, Muthu

“…Sarcolipin is a novel regulator of cardiac sarcoplasmic reticulum Ca²⁺ ATPase 2a (SERCA2a) and is expressed abundantly in atria. In this study we investigated…”
Get full text

Monoclonal Antibody to Marinobufagenin Downregulates TGFβ Profibrotic Signaling in Left Ventricle and Kidney and Reduces Tissue Remodeling in Salt-Sensitive Hypertension by Zhang, Yongqing, Wei, Wen, Shilova, Victoria, Petrashevskaya, Natalia N, Zernetkina, Valentina I, Grigorova, Yulia N, Marshall, Courtney A, Fenner, Rachel C, Lehrmann, Elin, Wood, 3rd, William H, Becker, Kevin G, Lakatta, Edward G, Bagrov, Alexei Y, Fedorova, Olga V

“…Background Elevated levels of an endogenous Na/K-ATPase inhibitor marinobufagenin accompany salt-sensitive hypertension and are implicated in cardiac fibrosis…”
Get full text

Targeted Overexpression of Sarcolipin in the Mouse Heart Decreases Sarcoplasmic Reticulum Calcium Transport and Cardiac Contractility by Babu, Gopal J., Bhupathy, Poornima, Petrashevskaya, Natalia N., Wang, Honglan, Raman, Sripriya, Wheeler, Debra, Jagatheesan, Ganapathy, Wieczorek, David, Schwartz, Arnold, Janssen, Paul M.L., Ziolo, Mark T., Periasamy, Muthu

“…The role of sarcolipin (SLN) in cardiac physiology was critically evaluated by generating a transgenic (TG) mouse model in which the SLN to…”
Get full text

Effects of ?1-adrenergic stimulation on normal and hypertrophied mouse hearts. Relation to caveolin-3 expression by PETRASHEVSKAYA, N

Get full text

Peroxisome proliferator-activated receptor ?/?: a new antihypertrophic drug target? by PETRASHEVSKAYA, N, SCHWARZ, A

Get full text

Cardiac function and electrical remodeling of the calcineurin-overexpressed transgenic mouse by PETRASHEVSKAYA, Natalia N, BODI, Ilona, RUBIO, Marta, MOLKENTIN, Jeffery D, SCHWARTZ, Arnold

“…To study the specificity of contractile phenotype and electrophysiological remodeling in transgenic (Tg) mice with cardiac directed calcineurin (phosphatase…”
Get full text

A small erythropoietin derived non-hematopoietic peptide reduces cardiac inflammation, attenuates age associated declines in heart function and prolongs healthspan by Winicki, Nolan M, Nanavati, Alay P, Morrell, Christopher H, Moen, Jack M, Axsom, Jessie E, Krawczyk, Melissa, Petrashevskaya, Natalia N, Beyman, Max G, Ramirez, Christopher, Alfaras, Irene, Mitchell, Sarah J, Juhaszova, Magdalena, Riordon, Daniel R, Wang, Mingyi, Zhang, Jing, Cerami, Anthony, Brines, Michael, Sollott, Steven J, de Cabo, Rafael, Lakatta, Edward G

“…Aging is associated with increased levels of reactive oxygen species and inflammation that disrupt proteostasis and mitochondrial function and leads to…”
Get full text

Peroxisome proliferator-activated receptor β/δ: a new antihypertrophic drug target? by Petrashevskaya, Natalia N., Schwarz, Arnold

Get full text

Electrical remodeling in hearts from a calcium-dependent mouse model of hypertrophy and failure: Complex nature of K+ current changes and action potential duration by BODI, Ilona, MUTH, James N, HAHN, Harvey S, PETRASHEVSKAYA, Natasha N, RUBIO, Marta, KOCH, Sheryl E, VARADI, Gyula, SCHWARTZ, Arnold

“…This study was designed to identify possible electrical remodeling (ER) in transgenic (Tg) mice with over-expressed L-type Ca(2+) channels. Transient outward…”
Get full text

Inhibition of protein kinase Cα improves myocardial β-adrenergic receptor signaling and ventricular function in a model of myocardial preservation by D’Souza, Karen M., PhD, Petrashevskaya, Natalia N., PhD, Merrill, Walter H., MD, Akhter, Shahab A., MD

“…Objective The specific effect of protein kinase Cα, the primary ventricular calcium-dependent protein kinase C isoform, on myocardial protection is unclear…”
Get full text

The importance of calcium in interpretation of NaK-ATPase isoform function in the mouse heart by Schwartz, A, Petrashevskaya, N N

Get full text

Calcium Cycling, Historic Overview and Perspectives. Role for Autonomic Nervous System Regulation by Petrashevskaya, Natalia N., Koch, Sheryl E., Bodi, Ilona, Schwartz, Arnold

“…N. N. Petrashevskaya, S. E. Koch, I. Bodi and A. Schwartz. Calcium Cycling, Historic Overview and Perspectives. Role for Autonomic Nervous System Regulation…”
Get full text

Presynaptic stimulus-release and postsynaptic compensatory changes in mice lacking the N-type calcium channel α(1B)-subunit by Petrashevskaya, Natalia N, Ishii, Masakazu, D'Souza, Karen, Koch, Sheryl E, Fuller-Bicer, Geraldine A, Schwartz, Arnold

“…N-type (Ca(v)2.2) voltage-dependent calcium channels (VDCC) play an important role in presynaptic neurotransmitter release in the autonomic nervous system and…”
Get full text

Reduction of [Ca(2+)](i) restores uncoupled beta-adrenergic signaling in isolated perfused transgenic mouse hearts by Serikov, V B, Petrashevskaya, N N, Canning, A M, Schwartz, A

“…The effects of alterations in calcium in the perfusion media were studied on ss-adrenergic coupling in isolated hearts from 3 different transgenic mice:…”
Get full text

Presynaptic stimulus-release and postsynaptic compensatory changes in mice lacking the N-type calcium channel α1B -subunit by Petrashevskaya, Natalia N, Ishii, Masakazu, D'Souza, Karen, Koch, Sheryl E, Fuller-Bicer, Geraldine A, Schwartz, Arnold

“…Abstract N-type (Cav 2.2) voltage-dependent calcium channels (VDCC) play an important role in presynaptic neurotransmitter release in the autonomic nervous…”
Get full text

AGE-DEPENDENT HYPERTENSION AND VASCULAR REMODELING IN DAHL-S RATS ARE ASSOCIATED WITH ELEVATED LEVELS OF MARINOBUFAGENIN AND COGNITIVE DECLINE by Fedorova, O., Grigorova, Y.N., Hagood, M., Mcdevitt, R., Long, J., Mcpherson, R., Naraine, A., Juhasz, O., Wei, W., Zernetkina, V., Petrashevskaya, N., Fishbein, K.W., Spencer, R.G., Rapp, P.R., Lakatta, E.G.

Get full text

Electrical remodeling in hearts from a calcium-dependent mouse model of hypertrophy and failure by Bodi, Ilona, Muth, James N, Hahn, Harvey S, Petrashevskaya, Natasha N, Rubio, Marta, Koch, Sheryl E, Varadi, Gyula, Schwartz, Arnold

“…This study was designed to identify possible electrical remodeling (ER) in transgenic (Tg) mice with over-expressed L-type Ca2+channels. Transient outward…”
Get full text

Effects of α1-adrenergic stimulation on normal and hypertrophied mouse hearts. Relation to caveolin-3 expression by PETRASHEVSKAYA, Natalia N, BODI, Ilona, KOCH, Sheryl E, AKHTER, Shahab A, SCHWARTZ, Arnold

Get full text

Reduction of [Ca2+]i Restores Uncoupled β-Adrenergic Signaling in Isolated Perfused Transgenic Mouse Hearts by Serikov, Vladimir B, Petrashevskaya, Natalia N, Canning, Amy M, Schwartz, Arnold

“…ABSTRACT—The effects of alterations in calcium in the perfusion media were studied on β-adrenergic coupling in isolated hearts from 3 different transgenic…”
Get full text