Search Results - "Petrara, Maria Raffaella"

Stronger and durable SARS-CoV-2 immune response to mRNA vaccines in 5–11 years old children with prior COVID-19 by Di Chiara, Costanza, Cantarutti, Anna, Raffaella Petrara, Maria, Bonfante, Francesco, Benetti, Elisa, Boracchini, Riccardo, Bosa, Luca, Carmona, Francesco, Cosma, Chiara, Cotugno, Nicola, Le Prevost, Marthe, Martini, Giorgia, Meneghel, Alessandra, Pagliari, Matteo, Palma, Paolo, Ruffoni, Elena, Zin, Annachiara, De Rossi, Anita, Giaquinto, Carlo, Donà, Daniele, Padoan, Andrea

“…mRNA vaccines elicit a durable humoral response to SARS-CoV-2 in adults, whereas evidence in children is scarce. This study aimed to assess the early and…”
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Asymptomatic and Mild SARS-CoV-2 Infections Elicit Lower Immune Activation and Higher Specific Neutralizing Antibodies in Children Than in Adults by Petrara, Maria Raffaella, Bonfante, Francesco, Costenaro, Paola, Cantarutti, Anna, Carmona, Francesco, Ruffoni, Elena, Di Chiara, Costanza, Zanchetta, Marisa, Barzon, Luisa, Donà, Daniele, Da Dalt, Liviana, Bortolami, Alessio, Pagliari, Matteo, Plebani, Mario, Rossi, Paolo, Cotugno, Nicola, Palma, Paolo, Giaquinto, Carlo, De Rossi, Anita

“…Background The immune response plays a pivotal role in dictating the clinical outcome in severe acute respiratory syndrome coronavirus 2 (SARS - CoV -…”
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Biological Aging and Immune Senescence in Children with Perinatally Acquired HIV by Giaquinto, C., Zanchetta, Marisa, Ballin, Giovanni, Petrara, Maria Raffaella, Dalzini, Annalisa, De Rossi, Anita

“…Chronic HIV-infected children suffer from premature aging and aging-related diseases. Viral replication induces an ongoing inflammation process, with the…”
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Early inflammation as a footprint of increased mortality risk in infants living with HIV from three African countries by Morrocchi, Elena, Pascucci, Giuseppe R., Cotugno, Nicola, Pighi, Chiara, Dominguez-Rodriguez, Sara, Petrara, Maria Raffaella, Tagarro, Alfredo, Kuhn, Louise, Cotton, Mark F., Otwombe, Kennedy, Lain, Maria G., Vaz, Paula, Barnabas, Shaun L., Spyer, Moira J., Lopez, Elisa, Fernández-Luis, Sheila, Nhampossa, Tacilta, Maiga, Almoustapha I., Dolo, Oumar, De Rossi, Anita, Rojo, Pablo, Giaquinto, Carlo, Lichterfeld, Mathias, Violari, Avy, Smit, Theresa, Behuhuma, Osee, Klein, Nigel, De Armas, Lesley, Pahwa, Savita, Rossi, Paolo, Palma, Paolo

“…In this work our aim was to identify early biomarkers in plasma samples associated with mortality in children with perinatal HIV treated early in life, to…”
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Immune Activation, Exhaustion and Senescence Profiles as Possible Predictors of Cancer in Liver Transplanted Patients by Petrara, Maria Raffaella, Shalaby, Sarah, Ruffoni, Elena, Taborelli, Martina, Carmona, Francesco, Giunco, Silvia, Del Bianco, Paola, Piselli, Pierluca, Serraino, Diego, Cillo, Umberto, Dolcetti, Riccardo, Burra, Patrizia, De Rossi, Anita

“…Liver transplanted (LT) patients for hepatocellular carcinoma (LT-HCC) or for other causes (LT-no-HCC) may develop post-transplantation malignancies. Although…”
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Impact of monotherapy on HIV-1 reservoir, immune activation, and co-infection with Epstein-Barr virus by Petrara, Maria Raffaella, Cattelan, Anna Maria, Sasset, Lolita, Freguja, Riccardo, Carmona, Francesco, Sanavia, Silvia, Zanchetta, Marisa, Del Bianco, Paola, De Rossi, Anita

“…Although monotherapy (mART) effectiveness in maintaining viral suppression and CD4 cell count has been extensively examined in HIV-1-infected patients, its…”
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Extra-telomeric functions of telomerase in the pathogenesis of Epstein-Barr virus-driven B-cell malignancies and potential therapeutic implications by Giunco, Silvia, Petrara, Maria Raffaella, Zangrossi, Manuela, Celeghin, Andrea, De Rossi, Anita

“…The Epstein-Barr virus (EBV) is a ubiquitous human γ-herpesvirus causally linked to a broad spectrum of both lymphoid and epithelial malignancies. In order to…”
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Post-transplant lymphoproliferative disorders: From epidemiology to pathogenesis-driven treatment by Petrara, Maria Raffaella, Giunco, Silvia, Serraino, Diego, Dolcetti, Riccardo, De Rossi, Anita

“…Highlights • PTLD represents the most severe complication of both hematopoietic stem cell and solid organ transplantations. • EBV is the main driver of PTLDs,…”
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Mild SARS-CoV-2 Infections and Neutralizing Antibody Titers by Bonfante, Francesco, Costenaro, Paola, Cantarutti, Anna, Di Chiara, Costanza, Bortolami, Alessio, Petrara, Maria Raffaella, Carmona, Francesco, Pagliari, Matteo, Cosma, Chiara, Cozzani, Sandra, Mazzetto, Eva, Di Salvo, Giovanni, Da Dalt, Liviana, Palma, Paolo, Barzon, Luisa, Corrao, Giovanni, Terregino, Calogero, Padoan, Andrea, Plebani, Mario, De Rossi, Anita, Donà, Daniele, Giaquinto, Carlo

“…BACKGROUND Recent evidence suggests that neutralizing antibodies (nAbs) to severe acute respiratory syndrome coronavirus 2 may persist over time; however,…”
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Accelerated aging in perinatally HIV-infected children: clinical manifestations and pathogenetic mechanisms by Chiappini, Elena, Bianconi, Martina, Dalzini, Annalisa, Petrara, Maria Raffaella, Galli, Luisa, Giaquinto, Carlo, De Rossi, Anita

“…Premature aging and related diseases have been documented in HIV-infected adults. Data are now emerging also regarding accelerated aging process in…”
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Premature aging and immune senescence in HIV-infected children by Gianesin, Ketty, Noguera-Julian, Antoni, Zanchetta, Marisa, Del Bianco, Paola, Petrara, Maria Raffaella, Freguja, Riccardo, Rampon, Osvalda, Fortuny, Clàudia, Camós, Mireia, Mozzo, Elena, Giaquinto, Carlo, De Rossi, Anita

“…OBJECTIVE:Several pieces of evidence indicate that HIV-infected adults undergo premature aging. The effect of HIV and antiretroviral therapy (ART) exposure on…”
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Short-Term TERT Inhibition Impairs Cellular Proliferation via a Telomere Length-Independent Mechanism and Can Be Exploited as a Potential Anticancer Approach by Amin, Aamir, Morello, Marzia, Petrara, Maria Raffaella, Rizzo, Beatrice, Argenton, Francesco, De Rossi, Anita, Giunco, Silvia

“…Telomerase reverse transcriptase (TERT), the catalytic component of telomerase, may also contribute to carcinogenesis via telomere-length independent…”
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HIV reservoir and premature aging: risk factors for aging-associated illnesses in adolescents and young adults with perinatally acquired HIV by Petrara, Maria Raffaella, Ruffoni, Elena, Carmona, Francesco, Cavallari, Ilaria, Zampieri, Sandra, Morello, Marzia, Del Bianco, Paola, Rampon, Osvalda, Cotugno, Nicola, Palma, Paolo, Rossi, Paolo, Giaquinto, Carlo, Giunco, Silvia, De Rossi, Anita

“…Despite receiving antiretroviral therapy (ART), an increasing number of adolescents and young adults with perinatally acquired HIV (PHIVAYA) are at risk of…”
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Immune activation, immune senescence and levels of Epstein Barr Virus in kidney transplant patients: Impact of mTOR inhibitors by Petrara, Maria Raffaella, Serraino, Diego, Di Bella, Caterina, Neri, Flavia, Del Bianco, Paola, Brutti, Martina, Carmona, Francesco, Ballin, Giovanni, Zanini, Stefano, Rigotti, Paolo, Furian, Lucrezia, De Rossi, Anita

“…Post-transplant lymphoproliferative disorders (PTLD) represent a severe complication in transplanted patients and Epstein-Barr Virus (EBV) is the main driver…”
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Hepatocellular carcinoma and the risk of cancer onset after liver transplantation-role of immune activation and aging profiles by Shalaby, Sarah, Petrara, Maria Raffaella, Ruffoni, Elena, Taborelli, Martina, Carmona, Francesco, Del Bianco, Paola, Piselli, Pierluca, D’Arcangelo, Francesca, Bizzaro, Debora, Senzolo, Marco, Russo, Francesco Paolo, Boccagni, Patrizia, Cillo, Umberto, Feltracco, Paolo, Serraino, Diego, De Rossi, Anita, Burra, Patrizia

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Pediatric Human Immunodeficiency Virus infection and cancer in the Highly Active Antiretroviral Treatment (HAART) era by Chiappini, Elena, Berti, Elettra, Gianesin, Ketty, Petrara, Maria Raffaella, Galli, Luisa, Giaquinto, Carlo, de Martino, Maurizio, De Rossi, Anita

“…Highlights • HAART has significantly improved life expectancy and quality in HIV-infected children. • HAART has reduced the AIDS-defining malignancies, but…”
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Long-term Immune Response to SARS-CoV-2 Infection Among Children and Adults After Mild Infection by Di Chiara, Costanza, Cantarutti, Anna, Costenaro, Paola, Donà, Daniele, Bonfante, Francesco, Cosma, Chiara, Ferrarese, Martina, Cozzani, Sandra, Petrara, Maria Raffaella, Carmona, Francesco, Liberati, Cecilia, Palma, Paolo, Di Salvo, Giovanni, De Rossi, Anita, Plebani, Mario, Padoan, Andrea, Giaquinto, Carlo

“…Importance Understanding the long-term immune response against SARS-CoV-2 infection in children is crucial to optimize vaccination strategies. Although it is…”
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Virological and immunological features of SARS-CoV-2-infected children who develop neutralizing antibodies by Cotugno, Nicola, Ruggiero, Alessandra, Bonfante, Francesco, Petrara, Maria Raffaella, Zicari, Sonia, Pascucci, Giuseppe Rubens, Zangari, Paola, De Ioris, Maria Antonietta, Santilli, Veronica, Manno, E.C., Amodio, Donato, Bortolami, Alessio, Pagliari, Matteo, Concato, Carlo, Linardos, Giulia, Campana, Andrea, Donà, Daniele, Giaquinto, Carlo, Bernardi, Stefania, Romani, Lorenza, Pansa, Paola, Chiurchiú, Sara, Finocchi, Andrea, Cancrini, Caterina, Lancella, Laura, Cursi, Laura, De Luca, Maia, Cutrera, Renato, Sessa, Libera, Morrocchi, Elena, Medri, Chiara, Putignani, Lorenza, Calò Carducci, F.I., D’Argenio, Patrizia, Ciofi degli Atti, Marta, D’Amore, Carmen, Piccioni, Livia, Di Giuseppe, Martina, Jenkner, Alessandro, Giancotta, Carmela, Krzysztofiak, Andrzej, Brodin, Petter, Rossi, Paolo, De Rossi, Anita, Palma, Paolo

“…As the global COVID-19 pandemic progresses, it is paramount to gain knowledge on adaptive immunity to SARS-CoV-2 in children to define immune correlates of…”
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Immune senescence and immune activation in elderly colorectal cancer patients by Giunco, Silvia, Petrara, Maria Raffaella, Bergamo, Francesca, Del Bianco, Paola, Zanchetta, Marisa, Carmona, Francesco, Zagonel, Vittorina, De Rossi, Anita, Lonardi, Sara

“…In our previous study, we found that low thymic output and short telomere length were associated with a higher risk of tumor in elderly cancer patients. Here,…”
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Size of HIV‐1 reservoir is associated with telomere shortening and immunosenescence in early‐treated European children with perinatally acquired HIV‐1 by Dalzini, Annalisa, Ballin, Giovanni, Dominguez‐Rodriguez, Sara, Rojo, Pablo, Petrara, Maria Raffaella, Foster, Caroline, Cotugno, Nicola, Ruggiero, Alessandra, Nastouli, Eleni, Klein, Nigel, Rinaldi, Stefano, Pahwa, Savita, Rossi, Paolo, Giaquinto, Carlo, Palma, Paolo, De Rossi, Anita

“…Introduction Persistence of HIV‐1, causing chronic immune activation, is a key determinant of premature senescence. Early antiretroviral therapy (ART) has been…”
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