Search Results - "Petrackova, Martina"
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Properties of bcr-abl-transformed mouse 12B1 cells secreting interleukin-2 and granulocyte-macrophage colony stimulating factor (GM-CSF): II. Adverse effects of GM-CSF
Published in International journal of oncology (01-06-2012)“…Granulocyte-macrophage colony stimulating factor (GM-CSF) is considered to be the most effective immunostimulating factor for the construction of…”
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NPM1 and DNMT3A mutations are associated with distinct blast immunophenotype in acute myeloid leukemia
Published in Oncoimmunology (31-12-2022)“…The immune system is important for elimination of residual leukemic cells during acute myeloid leukemia (AML) therapy. Anti-leukemia immune response can be…”
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Characterization of the input material quality for the production of tisagenlecleucel by multiparameter flow cytometry and its relation to the clinical outcome
Published in Pathology oncology research (20-04-2023)“…Tisagenlecleucel (tisa-cel) is a CD19 specific CAR-T cell product approved for the treatment of relapsed/refractory (r/r) DLBCL or B-ALL. We have followed a…”
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Immunology of chronic myeloid leukemia: current concepts and future goals
Published in Expert review of clinical immunology (01-04-2015)“…Although chronic myeloid leukemia is a rare malignancy, it has developed into a model system for the study of a variety of aspects of cancer biology and…”
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Tumor Protective Activity of CD4+ but Not of CD8+ T Cells in DNA-Vaccinated Mice Challenged with bcr-abl-Transformed Cells
Published in Clinical & developmental immunology (01-01-2013)“…In the recent past, it has repeatedly been reported that CD4 cells play an important role in the immunology of chronic myeloid leukaemia. It was therefore of…”
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Properties of bcr-abl-transformed mouse 12B1 cells secreting interleukin-2 and granulocyte-macrophage colony-stimulating factor: I. Derivation, genetic stability, oncogenicity and immunogenicity
Published in International journal of oncology (01-05-2012)“…The highly oncogenic bcr-abl-transformed mouse (Balb/c) 12B1 cells were transfected with plasmids carrying genes for either mouse interleukin-2 (IL‑2) or the…”
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Predictive value of serum cytokine levels in chronic myeloid leukemia patients
Published in Immunology letters (01-11-2016)“…Highlights • Cytokine levels in CML patients at diagnosis and therapy outcome were related. • MCP-1 levels were significantly higher in patients with optimal…”
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Protein Profiling of Two Mouse BCR-ABL-Transformed Cell Lines
Published in Blood (18-11-2011)“…Abstract 4720 Our efforts aim at the development of effective experimental vaccines against bcr-abl-transformed cells. For our study two mouse (Balb/c)…”
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Unexpected properties of endostatin-producing mouse BCR-ABL-transformed cells
Published in International journal of oncology (01-02-2012)“…We investigated whether a genetic modification of BCR-ABL-transformed mouse cells that resulted in endostatin (ES) production altered their oncogenic…”
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Intracellular Cytokines Produced by Stimulated CD3+ Cells from Chronic Myeloid Leukemia Patients
Published in Acta haematologica (01-01-2017)“…Our work examined the production of intracellular interferon (INF)-γ, tumor necrosis factor (TNF)-α, interleukin (IL)-2, and IL-4 by in vitro stimulated CD3+…”
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Kynurenine and uric acid levels in chronic myeloid leukemia patients
Published in Oncoimmunology (01-03-2015)“…Indoleamine 2,3-dioxygenase 1 (IDO1), IDO2 and tryptophan 2,3-dioxygenase (TDO) represent some of the key immune regulators. Their increased activity has been…”
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Combined chemo-and immunotherapy of tumors induced in mice by bcr-abl-transformed cells
Published in Oncology reports (01-03-2009)“…For our experiments we selected two oncogenic, bcr-abl-transformed mouse cell lines, viz. B210 and 12B1. Both cell types are capable of inducing leukemia-like…”
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Tumor Protective Activity of CD4+ but Not of CD8+ T Cells in DNA-Vaccinated Mice Challenged with bcr-abl-Transformed Cells
Published in Clinical & developmental immunology (2013)“…In the recent past, it has repeatedly been reported that CD4 cells play an important role in the immunology of chronic myeloid leukaemia. It was therefore of…”
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Journal Article