Search Results - "Petra Pospíšilová"
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MLST typing of Treponema pallidum subsp. pallidum in the Czech Republic during 2004-2017: Clinical isolates belonged to 25 allelic profiles and harbored 8 novel allelic variants
Published in PloS one (31-05-2019)“…A recently introduced Multilocus Sequence Typing scheme for Treponema pallidum subsp. pallidum was applied to clinical samples collected from 2004 to 2017 from…”
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Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens
Published in Frontiers in microbiology (31-07-2019)“…Syphilis, caused by subsp. (TPA), remains an important public health problem with an increasing worldwide prevalence. Despite recent advances in cultivation,…”
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A retrospective study on nested PCR detection of syphilis treponemes in clinical samples: PCR detection contributes to the diagnosis of syphilis in patients with seronegative and serodiscrepant results
Published in PloS one (20-08-2020)“…Syphilis, caused by Treponema pallidum ssp. pallidum (TPA), is a persisting global health problem. Although syphilis diagnostics relies mainly on serology,…”
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Treponema pallidum subsp. pallidum strains DAL-1 and Philadelphia 1 differ in generation times in vitro as well as during experimental rabbit infection
Published in PloS one (24-05-2024)“…In this work, we determined that Treponema pallidum subsp. pallidum (TPA) DAL-1 (belonging to Nichols-like group of TPA strains) grew 1.53 (± 0.08) times…”
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Importance of repeated sampling: vegetation analyses after 10 years revealed different restoration trends in formerly extracted peatlands
Published in Restoration ecology (01-03-2023)“…The chronosequence approach, that is, analyses of several stages differing in age since disturbance or restoration but more or less comparable in site…”
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Sequence typing of Haemophilus ducreyi isolated from patients in the Namatanai region of Papua New Guinea: Infections by Class I and Class II strain types differ in ulcer duration and resurgence of infection after azithromycin treatment
Published in PLoS neglected tropical diseases (15-08-2024)“…Haemophilus ducreyi (HD) is an important cause of cutaneous ulcers in several endemic regions, including the Western Pacific Region, especially among children…”
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The hare syphilis agent is related to, but distinct from, the treponeme causing rabbit syphilis
Published in PloS one (12-08-2024)“…The treponemes infecting lagomorphs include Treponema paraluisleporidarum ecovar Cuniculus (TPeC) and ecovar Lepus (TPeL), infecting rabbits and hares,…”
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Low genetic diversity of Treponema pallidum ssp. pertenue (TPE) isolated from patients' ulcers in Namatanai District of Papua New Guinea: Local human population is infected by three TPE genotypes
Published in PLoS neglected tropical diseases (01-01-2024)“…Yaws is an endemic disease caused by Treponema pallidum subsp. pertenue (TPE) that primarily affects children in rural regions of the tropics. The endemic…”
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Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters
Published in PloS one (10-09-2013)“…Treponema pallidum ssp. pallidum (TPA), the causative agent of syphilis, is a highly clonal bacterium showing minimal genetic variability in the genome…”
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Macrolide resistance in yaws
Published in The Lancet (British edition) (21-04-2018)“…The mutation, A2059G, was previously reported in a patient with syphilis (caused by T p pallidum) with spiramycin treatment failure;2 it is one of two…”
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Alien species in vegetation succession: participation, temporal trends and determining factors in various central European series
Published in Biological invasions (01-11-2021)“…A systematic analysis of vegetation successions following disturbance can outline general invasion patterns and contribute to the management of disturbed and…”
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Majority of Treponema pallidum ssp. pallidum MLST allelic profiles in the Czech Republic (2004–2022) belong to two SS14-like clusters
Published in Scientific reports (29-07-2024)“…Syphilis is a multistage sexually transmitted disease caused by Treponema pallidum ssp. pallidum . In the Czech Republic, there are around 700–800 new syphilis…”
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Analysis of Treponema pallidum Strains From China Using Improved Methods for Whole-Genome Sequencing From Primary Syphilis Chancres
Published in The Journal of infectious diseases (03-03-2021)“…Abstract Background Whole-genome sequencing (WGS) of Treponema pallidum subspecies pallidum (TPA) has been constrained by the lack of in vitro cultivation…”
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Coinfection of a yaws patient with two closely related Treponema pallidum subsp. pertenue strains: A rare event with potential evolutionary implications
Published in Acta tropica (01-08-2024)“…•Multiple studies reported inter-strain recombination events in Treponema pallidum.•Treponema pallidum lacks vectors for horizontal DNA transfer.•Here, we…”
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Identification of positively selected genes in human pathogenic treponemes: Syphilis-, yaws-, and bejel-causing strains differ in sets of genes showing adaptive evolution
Published in PLoS neglected tropical diseases (01-06-2019)“…Pathogenic treponemes related to Treponema pallidum are both human (causing syphilis, yaws, bejel) and animal pathogens (infections of primates, venereal…”
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Whole genome sequences of three Treponema pallidum ssp. pertenue strains: yaws and syphilis treponemes differ in less than 0.2% of the genome sequence
Published in PLoS neglected tropical diseases (01-01-2012)“…The yaws treponemes, Treponema pallidum ssp. pertenue (TPE) strains, are closely related to syphilis causing strains of Treponema pallidum ssp. pallidum (TPA)…”
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Whole genome sequence of Treponema pallidum ssp. pallidum, strain Mexico A, suggests recombination between yaws and syphilis strains
Published in PLoS neglected tropical diseases (01-09-2012)“…Treponema pallidum ssp. pallidum (TPA), the causative agent of syphilis, and Treponema pallidum ssp. pertenue (TPE), the causative agent of yaws, are closely…”
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Genome analysis of Treponema pallidum subsp. pallidum and subsp. pertenue strains: most of the genetic differences are localized in six regions
Published in PloS one (29-12-2010)“…The genomes of eight treponemes including T. p. pallidum strains (Nichols, SS14, DAL-1 and Mexico A), T. p. pertenue strains (Samoa D, CDC-2 and Gauthier), and…”
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Comparison of CDC and sequence-based molecular typing of syphilis treponemes: tpr and arp loci are variable in multiple samples from the same patient
Published in BMC microbiology (30-07-2013)“…Molecular typing of syphilis-causing strains provides important epidemiologic data. We tested whether identified molecular subtypes were identical in…”
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Whole genome sequence of the Treponema Fribourg-Blanc: unspecified simian isolate is highly similar to the yaws subspecies
Published in PLoS neglected tropical diseases (01-04-2013)“…Unclassified simian strain Treponema Fribourg-Blanc was isolated in 1966 from baboons (Papio cynocephalus) in West Africa. This strain was morphologically…”
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