Search Results - "Petkovic, Vibor"
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Butyrate increases intracellular calcium levels and enhances growth hormone release from rat anterior pituitary cells via the G-protein-coupled receptors GPR41 and 43
Published in PloS one (13-10-2014)“…Butyrate is a short-chain fatty acid (SCFA) closely related to the ketone body ß-hydroxybutyrate (BHB), which is considered to be the major energy substrate…”
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2
Effect of Zinc Binding Residues in Growth Hormone (GH) and Altered Intracellular Zinc Content on Regulated GH Secretion
Published in Endocrinology (Philadelphia) (01-11-2013)“…Endocrine cells store hormones in concentrated forms (aggregates) in dense-core secretory granules that are released upon appropriate stimulation. Zn2+ binding…”
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Transient Neonatal Zinc Deficiency Caused by a Heterozygous G87R Mutation in the Zinc Transporter ZnT-2 (SLC30A2) Gene in the Mother Highlighting the Importance of Zn^(2+) for Normal Growth and Development
Published in International Journal of Endocrinology (2013)“…Suboptimal dietary zinc (Zn(2+)) intake is increasingly appreciated as an important public health issue. Zn(2+) is an essential mineral, and infants are…”
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4
A rich chemokine environment strongly enhances leukocyte migration and activities
Published in Blood (01-05-2005)“…The migration of leukocytes in immune surveillance and inflammation is largely determined by their response to chemokines. While the chemokine specificities…”
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Transient Neonatal Zinc Deficiency Caused by a Heterozygous G87R Mutation in the Zinc Transporter ZnT-2 (SLC30A2) Gene in the Mother Highlighting the Importance of Zn2+ for Normal Growth and Development
Published in International journal of endocrinology (01-01-2013)“…Suboptimal dietary zinc (Zn2+) intake is increasingly appreciated as an important public health issue. Zn2+ is an essential mineral, and infants are…”
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6
Alteration of ZnT5-mediated zinc import into the early secretory pathway affects the secretion of growth hormone from rat pituitary cells
Published in Hormone research in paediatrics (01-01-2014)“…Aggregation of growth hormone (GH) required for its proper storage in granules is facilitated by zinc (Zn(2+)) transported by specific zinc transporters in and…”
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Growth Hormone (GH)-Releasing Hormone Increases the Expression of the Dominant-Negative GH Isoform in Cases of Isolated GH Deficiency due to GH Splice-Site Mutations
Published in Endocrinology (Philadelphia) (01-06-2010)“…An autosomal dominant form of isolated GH deficiency (IGHD II) can result from heterozygous splice site mutations that weaken recognition of exon 3 leading to…”
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Isolated GH Deficiency Type II: Knockdown of the Harmful Δ3GH Recovers wt-GH Secretion in Rat Tumor Pituitary Cells
Published in Endocrinology (Philadelphia) (01-09-2010)“…Isolated GH deficiency type II (IGHD II) is the autosomal dominant form of GHD. In the majority of the cases, this disorder is due to specific GH-1 gene…”
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9
I-TAC/CXCL11 is a natural antagonist for CCR5
Published in Journal of leukocyte biology (01-09-2004)“…The selective CXC chemokine receptor 3 (CXCR3) agonists, monokine induced by interferon‐γ (IFN‐ γ)/CXC chemokine ligand 9 (CXCL9), IFN‐inducible protein…”
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Isolated growth hormone deficiency type 2: from gene to therapy
Published in Endocrine development (01-01-2012)“…Isolated growth hormone deficiency type-2 (IGHD-2), the autosomal-dominant form of GH deficiency, is mainly caused by specific splicing mutations in the human…”
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11
Eotaxin-3/CCL26 Is a Natural Antagonist for CC Chemokine Receptors 1 and 5
Published in The Journal of biological chemistry (01-05-2004)“…Eotaxin-3 (CCL26), like eotaxin (CCL11) and eotaxin-2 (CCL24), has long been considered a specific agonist for CC chemokine receptor 3 (CCR3), attracting and…”
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12
ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression
Published in Blood (15-04-2006)“…Tightly regulated expression of the transcription factor PU.1 is crucial for normal hematopoiesis. PU.1 knockdown mice develop acute myeloid leukemia (AML),…”
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Rescue of Isolated GH Deficiency Type II (IGHD II) via Pharmacologic Modulation of GH-1 Splicing
Published in Endocrinology (Philadelphia) (01-10-2016)“…Isolated GH deficiency (IGHD) type II, the autosomal dominant form of GHD, is mainly caused by mutations that affect splicing of GH-1. When misspliced RNA is…”
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14
Deficient CEBPA DNA binding function in normal karyotype AML patients is associated with favorable prognosis
Published in Blood (05-05-2011)“…CCAAT/enhancer binding protein-α (CEBPA) mutations in acute myeloid leukemia (AML) patients with a normal karyotype (NK) confer favorable prognosis, whereas…”
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15
Synergy-inducing chemokines enhance CCR2 ligand activities on monocytes
Published in European journal of immunology (01-04-2009)“…The migration of monocytes to sites of inflammation is largely determined by their response to chemokines. Although the chemokine specificities and expression…”
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16
Influence of Growth Hormone (GH) Receptor Deletion of Exon 3 and Full-Length Isoforms on GH Response and Final Height in Patients with Severe GH Deficiency
Published in The journal of clinical endocrinology and metabolism (01-03-2008)“…Context: A polymorphism of the GH receptor (GHR) gene resulting in genomic deletion of exon 3 (GHR-d3) has been associated with responsiveness to GH therapy…”
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Eotaxin-3/CCL26 is a natural antagonist for CC chemokine receptors 1 and 5. A human chemokine with a regulatory role
Published in The Journal of biological chemistry (28-05-2004)“…Eotaxin-3 (CCL26), like eotaxin (CCL11) and eotaxin-2 (CCL24), has long been considered a specific agonist for CC chemokine receptor 3 (CCR3), attracting and…”
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18
The role of zinc dynamics in growth hormone secretion
Published in Hormone research in paediatrics (01-01-2013)“…Human growth hormone (GH) causes a variety of physiological and metabolic effects in humans and plays a pivotal role in postnatal growth. In somatotroph cells…”
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19
Heterozygous GHR gene mutation in a child with idiopathic short stature
Published in Journal of pediatric endocrinology & metabolism : JPEM (01-03-2014)“…Several monogenic defects have been reported to be associated with idiopathic short stature. Focusing on growth hormone receptor (GHR)-gene alterations, the…”
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Growth Hormone (GH) Deficiency Type II: A Novel GH-1 Gene Mutation (GH-R178H) Affecting Secretion and Action
Published in The journal of clinical endocrinology and metabolism (01-02-2010)“…Context and Objective: Main features of the autosomal dominant form of GH deficiency (IGHD II) include markedly reduced secretion of GH combined with low…”
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