Search Results - "Petiti, Juan Pablo"
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Association of PTP4A3 expression and tumour size in functioning pituitary adenoma: a descriptive study
Published in Journal of clinical pathology (01-03-2021)“…PTP4A3 is a subclass of a protein tyrosine phosphatase super family and is expressed in a range of epithelial neoplasms. We evaluated PTP4A3 expression and its…”
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Involvement of MEK/ERK1/2 and PI3K/Akt Pathways in the Refractory Behavior of GH3B6 Pituitary Tumor Cells to the Inhibitory Effect of TGFβ1
Published in Endocrinology (Philadelphia) (01-02-2015)“…Pituitary tumor cells have a poor response to the growth inhibitory effect of TGFβ1, possibly resulting from the cross talk of TGFβ/Smads signal with other…”
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Editorial: From genetic alterations to new molecular targets in pituitary disorders
Published in Frontiers in endocrinology (Lausanne) (07-02-2024)Get full text
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Cuprous oxide nanoparticles incorporated into a polymeric matrix embedded in fabrics to prevent spread of SARS-CoV-2
Published in International journal of pharmaceutics (05-04-2023)“…[Display omitted] •Cotton and PP fabrics coated with a chitosan matrix containing Cu2O@SDS NPs were developed.•The coating of the fabrics was carried out by…”
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Changes of stem cell niche during experimental pituitary tumor development
Published in Journal of neuroendocrinology (01-12-2021)“…To investigate the putative stem cell/tumor stem cell (SC/TSC) niche contribution to hyperplasic/adenomatous pituitary lesions, we analyzed variation in the…”
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Oxidative stress and mitochondrial adaptive shift during pituitary tumoral growth
Published in Free radical biology & medicine (20-05-2018)“…The cellular transformation of normal functional cells to neoplastic ones implies alterations in the cellular metabolism and mitochondrial function in order to…”
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Regulation of FGF2-induced proliferation by inhibitory GPCR in normal pituitary cells
Published in Frontiers in endocrinology (Lausanne) (27-07-2023)“…Intracellular communication is essential for the maintenance of the anterior pituitary gland plasticity. The aim of this study was to evaluate whether GPCR-Gαi…”
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Trastuzumab inhibits pituitary tumor cell growth modulating the TGFB/SMAD2/3 pathway
Published in Endocrine-related cancer (01-10-2018)“…In pituitary adenomas, early recurrences and resistance to conventional pharmacotherapies are common, but the mechanisms involved are still not understood. The…”
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Evidence of cellular senescence during the development of estrogen-induced pituitary tumors
Published in Endocrine-related cancer (01-06-2015)“…Although pituitary adenomas represent 25% of intracranial tumors, they are usually benign, with the mechanisms by which these tumors usually avoid an invasive…”
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10
Testosterone abrogates TLR4 activation in prostate smooth muscle cells contributing to the preservation of a differentiated phenotype
Published in Journal of cellular physiology (01-07-2013)“…Prostate smooth muscle cells (pSMCs) are capable of responding to inflammatory stimuli by secreting proinflammatory products, which causes pSMCs to undergo…”
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The expansion of adult stem/progenitor cells and their marker expression fluctuations are linked with pituitary plastic adaptation during gestation and lactancy
Published in American journal of physiology: endocrinology and metabolism (01-08-2016)“…Extensive evidence has revealed variations in the number of hormone-producing cells in the pituitary gland, which occur under physiological conditions such as…”
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Functional Toll-like receptor 4 expressed in lactotrophs mediates LPS-induced proliferation in experimental pituitary hyperplasia
Published in Experimental cell research (15-11-2013)“…Toll like receptor 4 (TLR4) has been characterized for its ability to recognize bacterial endotoxin lipopolysaccharide (LPS). Considering that infections or…”
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Bromocriptine induces parapoptosis as the main type of cell death responsible for experimental pituitary tumor shrinkage
Published in Toxicology and applied pharmacology (01-10-2009)“…Bromocriptine (Bc) produces pituitary tumoral mass regression which induces the cellular death that was classically described as apoptosis. However, recent…”
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GH3B6 Pituitary Tumor Cell Proliferation is Mediated by PKCα and PKCε via ERK 1/2-dependent Pathway
Published in Cellular physiology and biochemistry (01-01-2010)“…Background: In this report, we explored the role of PKCα and PKCε as mediators of phorbol 12-myristate13-acetate (PMA)-induced proliferation in pituitary tumor…”
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Specific subcellular targeting of PKCα and PKCε in normal and tumoral lactotroph cells by PMA-mitogenic stimulus
Published in Journal of molecular histology (2009)“…The variations of the intracellular localization of the individual protein kinase C (PKC) isoforms are related with their different biological functions. In…”
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Antagonic effects of oestradiol in interaction with IGF-1 on proliferation of lactotroph cells in vitro
Published in Histochemistry and cell biology (01-09-2005)“…The effects of IGF-1, 17 beta oestradiol and its functional interaction on lactotrophs cell proliferation were evaluated. In addition we investigated the…”
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ERRATUM: Evidence of cellular senescence during the development of estrogen-induced pituitary tumors
Published in Endocrine-related cancer (01-10-2022)Get full text
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TGFβ1 regulates prolactin secretion during postnatal development: gender differences
Published in Journal of endocrinology (01-07-2020)“…Serum prolactin levels gradually increase from birth to puberty in both male and female rats, with higher levels observed in female since the first days of…”
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Ultrastructural and Molecular Evidence of Macroautophagy in Functioning PitNETs and Experimental Pituitary Tumors
Published in Neuroendocrinology (01-07-2023)“…Macroautophagy is a lysosome-mediated degradation process that controls the quality of cytoplasmic components and organelles, with its regulation depending on…”
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The epigenetic EZH2/H3K27me3 axis modulates lactotroph tumor cell proliferation
Published in Journal of endocrinology (01-05-2023)“…Interest in epigenetics has gained substantial momentum as a result of their identified role in the regulation of tumor progression, as well as their ability…”
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