Search Results - "Petit, Rebecca S."

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    Restriction of Receptor Movement Alters Cellular Response: Physical Force Sensing by EphA2 by Salaita, Khalid, Nair, Pradeep M, Petit, Rebecca S, Neve, Richard M, Das, Debopriya, Gray, Joe W, Groves, Jay T

    “…Activation of the EphA2 receptor tyrosine kinase by ephrin-A1 ligands presented on apposed cell surfaces plays important roles in development and exhibits…”
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    Journal Article
  2. 2

    T-cell triggering thresholds are modulated by the number of antigen within individual T-cell receptor clusters by Manz, Boryana N, Jackson, Bryan L, Petit, Rebecca S, Dustin, Michael L, Groves, Jay

    “…T cells react to extremely small numbers of activating agonist peptides. Spatial organization of T-cell receptors (TCR) and their peptide-major…”
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    EphA2 Receptor Activation by Monomeric Ephrin-A1 on Supported Membranes by Xu, Qian, Lin, Wan-Chen, Petit, Rebecca S., Groves, Jay T.

    Published in Biophysical journal (07-12-2011)
    “…The receptor tyrosine kinase EphA2 interacts with its glycosylphosphatidylinositol (GPI)-linked ephrin-A1 ligand in a juxtacrine configuration. The soluble…”
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    Journal Article
  5. 5

    Using patterned supported lipid membranes to investigate the role of receptor organization in intercellular signaling by Nair, Pradeep M, Salaita, Khalid, Petit, Rebecca S, Groves, Jay T

    Published in Nature protocols (01-04-2011)
    “…Physical inputs, both internal and external to a cell, can directly alter the spatial organization of cell surface receptors and their associated functions…”
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    Journal Article
  6. 6

    Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells by Smoligovets, Alexander A, Smith, Adam W, Wu, Hung-Jen, Petit, Rebecca S, Groves, Jay T

    Published in Journal of cell science (01-02-2012)
    “…T cell triggering through T-cell antigen receptors (TCRs) results in spatial assembly of the receptors on multiple length scales. This assembly is mediated by…”
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