Search Results - "Petit, Constance S"

Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases by Petit, Constance S, Roczniak-Ferguson, Agnes, Ferguson, Shawn M

“…Birt-Hogg-Dubé syndrome, a human disease characterized by fibrofolliculomas (hair follicle tumors) as well as a strong predisposition toward the development of…”
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The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis by Roczniak-Ferguson, Agnes, Petit, Constance S, Froehlich, Florian, Qian, Sharon, Ky, Jennifer, Angarola, Brittany, Walther, Tobias C, Ferguson, Shawn M

“…Lysosomes are the major cellular site for clearance of defective organelles and digestion of internalized material. Demand on lysosomal capacity can vary…”
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Epidermal growth factor receptor is involved in enterocyte anoikis through the dismantling of E-cadherin-mediated junctions by Lugo-Martínez, Verónica-Haydée, Petit, Constance S, Fouquet, Stéphane, Le Beyec, Johanne, Chambaz, Jean, Pinçon-Raymond, Martine, Cardot, Philippe, Thenet, Sophie

“…Enterocytes of the intestinal epithelium are continually regenerated. They arise from precursor cells in crypts, migrate along villi, and finally die, 3-4 days…”
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Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration by Petit, Constance S., Lee, Jane J., Boland, Sebastian, Swarup, Sharan, Christiano, Romain, Lai, Zon Weng, Mejhert, Niklas, Elliott, Shane D., McFall, David, Haque, Sara, Huang, Eric J., Bronson, Roderick T., Harper, J. Wade, Farese, Robert V., Walther, Tobias C.

“…Numerous mutations that impair retrograde membrane trafficking between endosomes and the Golgi apparatus lead to neurodegenerative diseases. For example,…”
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Requirement of Cellular Prion Protein for Intestinal Barrier Function and Mislocalization in Patients With Inflammatory Bowel Disease by Petit, Constance S.V, Barreau, Frédérick, Besnier, Laura, Gandille, Pierre, Riveau, Béatrice, Chateau, Danielle, Roy, Maryline, Berrebi, Dominique, Svrcek, Magali, Cardot, Philippe, Rousset, Monique, Clair, Caroline, Thenet, Sophie

“…Background & Aims Cell adhesion is one function regulated by cellular prion protein (PrPc ), a ubiquitous, glycosylphosphatidylinositol-anchored glycoprotein…”
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Roles of the cellular prion protein in the regulation of cell-cell junctions and barrier function by Petit, Constance S.V., Besnier, Laura, Morel, Etienne, Rousset, Monique, Thenet, Sophie

“…The cellular prion protein was historically characterized owing to its misfolding in prion disease. Although its physiological role remains incompletely…”
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