Search Results - "Petheo, Gabor L"
-
1
Inhibition of TASK-1 potassium channel by phospholipase C
Published in American Journal of Physiology: Cell Physiology (01-08-2001)“…The two-pore-domain K(+) channel, TASK-1, was recently shown to be a target of receptor-mediated regulation in neurons and in adrenal glomerulosa cells. Here,…”
Get more information
Journal Article -
2
NOX5 in human spermatozoa: expression, function, and regulation
Published in The Journal of biological chemistry (16-03-2012)“…Physiological and pathological processes in spermatozoa involve the production of reactive oxygen species (ROS), but the identity of the ROS-producing enzyme…”
Get full text
Journal Article -
3
Interactions between electron and proton currents in excised patches from human eosinophils
Published in The Journal of general physiology (01-12-2003)“…The NADPH-oxidase is a plasma membrane enzyme complex that enables phagocytes to generate superoxide in order to kill invading pathogens, a critical step in…”
Get full text
Journal Article -
4
Molecular and functional characterization of Hv1 proton channel in human granulocytes
Published in PloS one (23-11-2010)“…Voltage-gated proton current (I(Hv)) has been characterized in several cell types, but the majority of the data was collected in phagocytes, especially in…”
Get full text
Journal Article -
5
A novel monoclonal antibody reveals the enrichment of NADPH oxidase 5 in human splenic endothelial cells
Published in Scientific reports (11-10-2023)“…Members of the NOX/DUOX family of NADPH oxidases are responsible for regulated ROS production in diverse cells and tissues. Detection of NOX/DUOX proteins at…”
Get full text
Journal Article -
6
Role of nucleotides and phosphoinositides in the stability of electron and proton currents associated with the phagocytic NADPH oxidase
Published in Biochemical journal (15-12-2006)“…The phagocytic NADPH oxidase (phox) moves electrons across cell membranes to kill microbes. The activity of this lethal enzyme is tightly regulated, but the…”
Get full text
Journal Article -
7
Reactive oxygen species‐mediated bacterial killing by B lymphocytes
Published in Journal of leukocyte biology (01-06-2015)“…Peritoneal B cells display high NADPH oxidase 2 activity; produced ROS contribute to bacterial killing during phagocytosis. Regulated production of ROS is…”
Get full text
Journal Article -
8
Disruption of the NOX5 Gene Aggravates Atherosclerosis in Rabbits
Published in Circulation research (30-04-2021)Get full text
Journal Article -
9
Electron and proton transport by NADPH oxidases
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (29-12-2005)“…The NADPH oxidase is the main weapon of phagocytic white blood cells that are the first line of defence of our body against invading pathogens, and patients…”
Get full text
Journal Article -
10
The Creation of a Multiallele Knockout Genotype in Rabbit Using CRISPR/Cas9 and Its Application in Translational Medicine
Published in Applied sciences (01-12-2020)“…Nonrodent animal models have recently become more valuable in preclinical studies. The limitation of nonrodent animal models is that they must demonstrate…”
Get full text
Journal Article -
11
Voltage- and NADPH-dependence of electron currents generated by the phagocytic NADPH oxidase
Published in Biochemical journal (01-06-2005)“…The phagocytic NADPH oxidase generates superoxide by transferring electrons from cytosolic NADPH to extracellular O2. The activity of the oxidase at the plasma…”
Get full text
Journal Article -
12
Inhibition of voltage-gated calcium channels by fluoxetine in rat hippocampal pyramidal cells
Published in Neuropharmacology (01-05-2000)“…Fluoxetine, an antidepressant which is used world-wide, is a prominent member of the class of selective serotonin re-uptake inhibitors. Recently, inhibition of…”
Get full text
Journal Article -
13
NOX5 in Human Spermatozoa
Published in The Journal of biological chemistry (16-03-2012)“…Physiological and pathological processes in spermatozoa involve the production of reactive oxygen species (ROS), but the identity of the ROS-producing enzyme…”
Get full text
Journal Article -
14
Role of Cell Volume in K+-Induced Ca2+ Signaling by Rat Adrenal Glomerulosa Cells
Published in Endocrinology (Philadelphia) (01-11-2003)“…The involvement of cell volume in the K+-evoked Ca2+ signaling was studied in cultured rat glomerulosa cells. Previously we reported that hyposmosis (250 mOsm)…”
Get full text
Journal Article -
15
Effects of osmotic changes on the chemoreceptor cell of rat carotid body
Published in The Journal of physiology (15-01-2003)“…The carotid body plays a crucial role in cardiorespiratory regulation. In the present study we investigated the effect of osmotic changes on cytoplasmic…”
Get full text
Journal Article -
16
A pH-sensitive chloride current in the chemoreceptor cell of rat carotid body
Published in The Journal of physiology (15-08-2001)“…Cardiorespiratory response to acidosis is initiated by the carotid body. The direct effect of extracellular pH (pH o ) on the chloride currents of isolated…”
Get full text
Journal Article -
17
Effect of Osmolarity on Aldosterone Production by Rat Adrenal Glomerulosa Cells
Published in Endocrinology (Philadelphia) (01-05-2000)“…Abstract The effect of osmotic changes on aldosterone production,[ Ca2+]i and voltage-gated Ca2+ currents, was studied in cultured rat glomerulosa cells…”
Get full text
Journal Article -
18
Molecular and Functional Characterization of H.sub.v1 Proton Channel in Human Granulocytes
Published in PloS one (23-11-2010)“…Voltage-gated proton current (I.sub.Hv) has been characterized in several cell types, but the majority of the data was collected in phagocytes, especially in…”
Get full text
Journal Article -
19
pH-sensitive inwardly rectifying chloride current in cultured rat cortical astrocytes
Published in Glia (01-04-2001)“…The effect of pHo on plasma membrane chloride current of cultured rat cortical astrocytes was investigated using the whole‐cell patch‐clamp technique. In the…”
Get full text
Journal Article -
20
Electrophysiological study on the high K+ sensitivity of rat glomerulosa cells
Published in Pflügers Archiv (01-02-1998)“…Elevation of extracellular potassium concentration by as little as some tenth of mM activates rat adrenal glomerulosa cells. In the present study some factors…”
Get full text
Journal Article