Search Results - "Petesch, Steven J"
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Overcoming the nucleosome barrier during transcript elongation
Published in Trends in genetics (01-06-2012)“…RNA polymerase II (Pol II) must break the nucleosomal barrier to gain access to DNA and transcribe genes efficiently. New single-molecule techniques have…”
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Activator-Induced Spread of Poly(ADP-Ribose) Polymerase Promotes Nucleosome Loss at Hsp70
Published in Molecular cell (13-01-2012)“…Eukaryotic cells possess many transcriptionally regulated mechanisms to alleviate the nucleosome barrier. Dramatic changes to the chromatin structure of…”
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Spt6 enhances the elongation rate of RNA polymerase II in vivo
Published in The EMBO journal (22-04-2009)“…Several eukaryotic transcription factors have been shown to modulate the elongation rate of RNA polymerase II (Pol II) on naked or chromatin‐reconstituted…”
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Rapid, Transcription-Independent Loss of Nucleosomes over a Large Chromatin Domain at Hsp70 Loci
Published in Cell (11-07-2008)“…To efficiently transcribe genes, RNA Polymerase II (Pol II) must overcome barriers imposed by nucleosomes and higher-order chromatin structure. Many genes,…”
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Extending the Marine Microcosm Laboratory
Published in Journal of chemical education (01-02-2007)“…The marine microcosm laboratory has been adopted in a range of analytical chemistry laboratory courses. Originally devised as a means to promote appreciation,…”
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Journal Article