Search Results - "Petersson, Joel"
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Outcomes and Strategies to Support a Treat-to-target Approach in Inflammatory Bowel Disease: A Systematic Review
Published in Journal of Crohn's and colitis (10-02-2020)“…Abstract Background and Aims Management of Crohn’s disease and ulcerative colitis has typically relied upon treatment intensification driven by symptoms alone…”
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inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
Published in Proceedings of the National Academy of Sciences - PNAS (30-09-2008)“…We normally live in symbiosis with ~10¹³ bacteria present in the colon. Among the several mechanisms maintaining the bacteria/host balance, there is limited…”
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Higher vs Standard Adalimumab Induction and Maintenance Dosing Regimens for Treatment of Ulcerative Colitis: SERENE UC Trial Results
Published in Gastroenterology (New York, N.Y. 1943) (01-06-2022)“…SERENE UC (Study of a Novel Approach to Induction and Maintenance Dosing With Adalimumab in Patients With Moderate to Severe Ulcerative Colitis) evaluated the…”
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Lactobacillus reuteri maintains a functional mucosal barrier during DSS treatment despite mucus layer dysfunction
Published in PloS one (27-09-2012)“…Treatment with the probiotic bacterium Lactobacillus reuteri has been shown to prevent dextran sodium sulfate (DSS)-induced colitis in rats. This is partly due…”
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Bacteria penetrate the inner mucus layer before inflammation in the dextran sulfate colitis model
Published in PloS one (18-08-2010)“…Protection of the large intestine with its enormous amount of commensal bacteria is a challenge that became easier to understand when we recently could…”
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Future directions in inflammatory bowel disease management
Published in Journal of Crohn's and colitis (01-08-2014)“…Clinical management of inflammatory bowel diseases (IBD), new treatment modalities and the potential impact of personalised medicine remain topics of intense…”
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iNOS-dependent increase in colonic mucus thickness in DSS-colitic rats
Published in PloS one (19-08-2013)“…To investigate colonic mucus thickness in vivo in health and during experimental inflammatory bowel disease. Colitis was induced with 5% DSS in drinking water…”
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Agreement of site and central readings of ileocolonoscopic scores in Crohn's disease: comparison using data from the EXTEND trial
Published in Gastrointestinal endoscopy (01-01-2016)“…Background and Aims Centralized endoscopic scoring may reduce variability, but evidence is lacking in patients with Crohn’s disease. We assessed the agreement…”
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Long-Term Safety of Adalimumab in Patients with Crohn's Disease: Final Data from Pyramid Registry
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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Adalimumab Long-Term Effectiveness in Adalimumab-Naïve Patients with Crohn's Disease: Final Data from Pyramid Registry
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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Adalimumab Efficacy and Safety by Disease Duration: Analysis of Pooled Studies of Crohn's Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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The gastric mucus layers: constituents and regulation of accumulation
Published in American journal of physiology: Gastrointestinal and liver physiology (01-10-2008)“…The mucus layer continuously covering the gastric mucosa consists of a loosely adherent layer that can be easily removed by suction, leaving a firmly adherent…”
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Dietary nitrate increases gastric mucosal blood flow and mucosal defense
Published in American journal of physiology: Gastrointestinal and liver physiology (01-03-2007)“…Salivary nitrate from dietary or endogenous sources is reduced to nitrite by oral bacteria. In the acidic stomach, nitrite is further reduced to bioactive…”
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Tu1914 PYRAMID Registry: An Observational Study of Adalimumab in Crohn's Disease: Results at Year 7
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2016)Get full text
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Effect of Adalimumab dose Escalation on Clinical, Health-related Quality of Life, Treatment Satisfaction and Work Productivity Outcomes Among Patients with Ulcerative Colitis in a Clinical Practice Setting: Results from Inspirada
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2017)Get full text
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