Search Results - "Peterson, Tara L."
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Identification of a potent and metabolically stable series of fluorinated diphenylpyridylethanamine-based cholesteryl ester transfer protein inhibitors
Published in Bioorganic & medicinal chemistry letters (15-10-2012)“…A novel series of diphenylpyridylethanamine-based inhibitors of cholesteryl ester transfer protein is described. Optimization of the urea moiety, particularly…”
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2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: Optimization via array synthesis
Published in Bioorganic & medicinal chemistry (15-04-2008)“…2-Arylbenzoxazole 5 was identified as a hit from a fluorescence-based high-throughput screen for CETP inhibitors. The synthesis and SAR investigation employing…”
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Ketene aminal-based lactam derivatives as a novel class of orally active FXa inhibitors
Published in Bioorganic & medicinal chemistry letters (15-12-2005)“…N, N′-Disubstituted ketene aminals are good bioisosteres of thiourea functional groups. We report the design and synthesis of a novel class of ketene…”
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