Search Results - "Peterson, Richard G"

Glucose dysregulation and response to common anti-diabetic agents in the FATZO/Pco mouse by Peterson, Richard G, Jackson, Charles Van, Zimmerman, Karen M, Alsina-Fernandez, Jorge, Michael, M Dodson, Emmerson, Paul J, Coskun, Tamer

“…The FATZO/Pco mouse is the result of a cross of the C57BL/6J and AKR/J strains. The crossing of these two strains and the selective inbreeding for obesity,…”
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The FATZO mouse, a next generation model of type 2 diabetes, develops NAFLD and NASH when fed a Western diet supplemented with fructose by Sun, Gao, Jackson, Charles V, Zimmerman, Karen, Zhang, Li-Kun, Finnearty, Courtney M, Sandusky, George E, Zhang, Guodong, Peterson, Richard G, Wang, Yi-Xin Jim

“…Metabolic disorders such as insulin resistance, obesity, and hyperglycemia are prominent risk factors for the development of non-alcoholic fatty liver disease…”
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Wound Healing Delay in the ZDSD Rat by Suckow, Mark A, Gobbett, Troy A, Peterson, Richard G

“…Animal models of diabetic delayed wound healing are essential to the development of strategies to improve clinical approaches for human patients. The Zucker…”
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Correlation of disease severity with body weight and high fat diet in the FATZO/Pco mouse by Droz, Brian A, Sneed, Bria L, Jackson, Charles V, Zimmerman, Karen M, Michael, M Dodson, Emmerson, Paul J, Coskun, Tamer, Peterson, Richard G

“…Obesity in many current pre-clinical animal models of obesity and diabetes is mediated by monogenic mutations; these are rarely associated with the development…”
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Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes by Huebert, Norman, de Winter, Willem, Zimmerman, Karen, Jackson, Charles V., Peterson, Richard G., Hansen, Michael K.

“…Metabolic syndrome and T2D produce significant health and economic issues. Many available animal models have monogenic leptin pathway mutations that are absent…”
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Impaired expression of neuronal nitric oxide synthase in the gracile nucleus is involved in neuropathic changes in Zucker Diabetic Fatty rats with and without 2,5-hexanedione intoxication by Ma, Sheng-Xing, Peterson, Richard G., Magee, Edward M., Lee, Paul, Lee, Wai-Nang Paul, Li, Xi-Yan

“…•We report selective impairment of nNOS expression in the gracile nucleus in ZDF rats.•nNOS expression is up-regulated in the gracile nucleus by 2,5-HD…”
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Characterization of Diabetic Neuropathy in the Zucker Diabetic Sprague-Dawley Rat: A New Animal Model for Type 2 Diabetes by Yorek, Mark A., Oltman, Christine L., Dake, Brian, Lupachyk, Sergey, Holmes, Amey, Coppey, Lawrence J., Davidson, Eric P., Peterson, Richard G.

“…Recently a new rat model for type 2 diabetes the Zucker diabetic Sprague-Dawley (ZDSD/Pco) was created. In this study we sought to characterize the development…”
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Analysis of the Zucker Diabetic Fatty (ZDF) Type 2 Diabetic Rat Model Suggests a Neurotrophic Role for Insulin/IGF-I in Diabetic Autonomic Neuropathy by Schmidt, Robert E., Dorsey, Denise A., Beaudet, Lucie N., Peterson, Richard G.

“…Dysfunction of the autonomic nervous system is a recognized complication of diabetes. Neuroaxonal dystrophy (NAD), a distinctive axonopathy involving distal…”
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Rosiglitazone reverses endothelial dysfunction but not remodeling of femoral artery in Zucker diabetic fatty rats by Lu, Xiao, Guo, Xiaomei, Karathanasis, Sotirios K, Zimmerman, Karen M, Onyia, Jude E, Peterson, Richard G, Kassab, Ghassan S

“…Endothelial dysfunction precedes atherogenesis and clinical complications in type 2 diabetes. The vascular dysfunction in Zucker diabetic fatty (ZDF) rats was…”
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Skeletal changes associated with the onset of type 2 diabetes in the ZDF and ZDSD rodent models by Reinwald, Susan, Peterson, Richard G, Allen, Matt R, Burr, David B

“…The incidence and prevalence of type 2 diabetes (T2D) continue to escalate at an unprecedented rate in the United States, particularly among populations with…”
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Molecular changes in hepatic metabolism in ZDSD rats–A new polygenic rodent model of obesity, metabolic syndrome, and diabetes by Han, Lu, Bittner, Stefanie, Dong, Dachuan, Cortez, Yuan, Bittner, Alex, Chan, Jackie, Umar, Meenakshi, Shen, Wen-Jun, Peterson, Richard G., Kraemer, Fredric B., Azhar, Salman

“…In recent years, the prevalence of obesity, metabolic syndrome and type 2 diabetes is increasing dramatically. They share pathophysiological mechanisms and…”
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The ZDSD rat: a novel model of diabetic nephropathy by Peterson, Richard G, Jackson, Charles Van, Zimmerman, Karen M

“…The ZDSD rat is a new obese-diabetic rat model that expresses type 2 diabetes in the presence of an intact leptin pathway. During a long pre-diabetic state,…”
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Effect of dietary fat on the development of non-insulin dependent diabetes mellitus in obese Zucker diabetic fatty male and female rats by Corsetti, James P., Sparks, Janet D., Peterson, Richard G., Smith, Robert L., Sparks, Charles E.

“…The obese Zucker diabetic fatty male rat (ZDF/Gmi™- fa) has become a widely used animal model of NIDDM, in contrast to the obese ZDF females that rarely…”
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Age-Related Differences in Response to High-Fat Feeding on Adipose Tissue and Metabolic Profile in ZDSD Rats by Davis, Jeremy E., Cain, James, Banz, William J., Peterson, Richard G.

“…The recruitment of new fat cells through adipogenesis may prevent the development of obesity-related comorbidities. However, adipogenic capacity is markedly…”
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Lipotoxic Nephropathy Is More Severe in Male than Female Rats N with Non-Insulin Diabetes Mellitus (NIDDM) by Dominguez, Jesus H, Xu, Wei, Hawes, John W, Peterson, Richard G

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Acarbose partially inhibits microvascular retinopathy in the Zucker Diabetic Fatty rat (ZDF/Gmi-fa) by Yang, Y S, Danis, R P, Peterson, R G, Dolan, P L, Wu, Y Q

“…We compared quantitative capillary retinopathic changes between non-insulin-dependent diabetic Zucker Diabetic Fatty (ZDF) rats and heterozygous nondiabetic…”
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A potent sorbitol dehydrogenase inhibitor exacerbates sympathetic autonomic neuropathy in rats with streptozotocin-induced diabetes by Schmidt, Robert E., Dorsey, Denise A., Beaudet, Lucie N., Parvin, Curtis A., Yarasheski, Kevin E., Smith, Samuel R., Williamson, Joseph R., Peterson, Richard G., Oates, Peter J.

“…We have developed an animal model of diabetic sympathetic autonomic neuropathy which is characterized by neuroaxonal dystrophy (NAD), an ultrastructurally…”
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Lipoprotein alterations in 10- and 20-week-old Zucker diabetic fatty rats: Hyperinsulinemic versus insulinopenic hyperglycemia by Sparks, Janet D., Phung, Thuy L., Bolognino, Mary, Cianci, Joanne, Khurana, Rohit, Peterson, Richard G., Sowden, Mark P., Corsetti, James P., Sparks, Charles E.

“…Lipoprotein and apolipoprotein parameters were studied in the male Zucker diabetic fatty (ZDF) rat at 10 and 20 weeks of age, corresponding to hyperinsulinemic…”
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"The reality of repressed memories": Comment by Peterson, Richard G.

“…Comments on E. F. Loftus's (see record 1993-37888-001) review of data on patients' recovery of repressed memories of sexual abuse in psychotherapy. Certain…”
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Incretin hormone expression in the gut of diabetic mice and rats by Berghöfer, Peter, Peterson, Richard G., Schneider, Kerstin, Fehmann, Hans C., Göke, Burkhard

“…To elucidate the question of whether production of the insulinotropic gut hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like…”
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