Search Results - "Peterson, Lisa A"
-
1
Context Matters: Contribution of Specific DNA Adducts to the Genotoxic Properties of the Tobacco-Specific Nitrosamine NNK
Published in Chemical research in toxicology (17-01-2017)“…The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) is a potent pulmonary carcinogen in laboratory animals. It is classified…”
Get full text
Journal Article -
2
Preoperative prediction model for risk of readmission after total joint replacement surgery: a random forest approach leveraging NLP and unfairness mitigation for improved patient care and cost-effectiveness
Published in Journal of orthopaedic surgery and research (10-05-2024)“…The Center for Medicare and Medicaid Services (CMS) imposes payment penalties for readmissions following total joint replacement surgeries. This study focuses…”
Get full text
Journal Article -
3
Reactive Metabolites in the Biotransformation of Molecules Containing a Furan Ring
Published in Chemical research in toxicology (18-01-2013)“…Many xenobiotics containing a furan ring are toxic and/or carcinogenic. The harmful effects of these compounds require furan ring oxidation. This reaction…”
Get full text
Journal Article -
4
Prenatal stress enhances NNK-induced lung tumors in A/J mice
Published in Carcinogenesis (New York) (31-12-2020)“…Abstract Children born to women who experience stress during pregnancy have an increased risk of cancer in later life, but no previous animal studies have…”
Get full text
Journal Article -
5
Life Cycle Environmental Impact of Underground Plastic Recharge Chambers in Stormwater Management
Published in Buildings (Basel) (01-06-2022)“…Life cycle assessment is used to systematically evaluate the environmental impact of underground plastic recharge chambers (RCs) used for stormwater…”
Get full text
Journal Article -
6
Assessing tobacco smoke exposure in pregnancy from self-report, urinary cotinine and NNAL: a validation study using the New Hampshire Birth Cohort Study
Published in BMJ open (07-02-2022)“…ObjectivesAccurate assessment of tobacco smoke exposure is key to evaluate its effects. We sought to validate and establish cut-offs for self-reported smoking…”
Get full text
Journal Article -
7
Electrophilic Intermediates Produced by Bioactivation of Furan
Published in Drug metabolism reviews (01-01-2006)“…The industrial and environmental chemical, furan, is a liver toxicant and carcinogen in laboratory animals. It has been classified as a possible human…”
Get full text
Journal Article Conference Proceeding -
8
Formation, Repair, and Genotoxic Properties of Bulky DNA Adducts Formed from Tobacco-Specific Nitrosamines
Published in Journal of Nucleic Acids (01-01-2010)“…4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and N′-nitrosonornicotine (NNN) are tobacco-specific nitrosamines present in tobacco products and smoke…”
Get full text
Journal Article -
9
An update on the formation in tobacco, toxicity and carcinogenicity of N'-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
Published in Carcinogenesis (New York) (19-05-2024)“…The tobacco-specific nitrosamines N'-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) are considered 'carcinogenic to humans'…”
Get full text
Journal Article -
10
GLUTATHIONE TRAPPING TO MEASURE MICROSOMAL OXIDATION OF FURAN TO CIS-2-BUTENE-1,4-DIAL
Published in Drug metabolism and disposition (01-10-2005)“…Furan is a liver carcinogen and toxicant. Furan is oxidized to the reactive dialdehyde, cis -2-butene-1,4-dial, by microsomal enzymes. This reactive metabolite…”
Get full text
Journal Article -
11
Depurinating Acylfulvene−DNA Adducts: Characterizing Cellular Chemical Reactions of a Selective Antitumor Agent
Published in Journal of the American Chemical Society (21-02-2007)“…Acylfulvenes (AFs) are a class of semisynthetic agents with high toxicity toward certain tumor cells, and for one analogue, hydroxymethylacylfulvene (HMAF),…”
Get full text
Journal Article -
12
Tobacco, e-cigarettes, and child health
Published in Current opinion in pediatrics (01-04-2017)“…The availability of the Children's Health Exposure Assessment Resource funded by the National Institute of Environmental Health Sciences provides new…”
Get full text
Journal Article -
13
Environmental and economic implications of stormwater management alternatives in rural development
Published in Journal of industrial ecology (01-08-2021)“…Floodplain restoration as a means of stormwater management (SWM) can benefit communities and the environment but is uncommonly chosen due to limited…”
Get full text
Journal Article -
14
Interindividual Differences in DNA Adduct Formation and Detoxification of 1,3-Butadiene-Derived Epoxide in Human HapMap Cell Lines
Published in Chemical research in toxicology (20-07-2020)“…Smoking-induced lung cancer is a major cause of cancer mortality in the US and worldwide. While 11–24% of smokers will develop lung cancer, risk varies among…”
Get full text
Journal Article -
15
Concentrations of Per- and Polyfluoroalkyl Substances in Paired Maternal Plasma and Human Milk in the New Hampshire Birth Cohort
Published in Environmental science & technology (10-01-2023)“…Per- and polyfluoroalkyl substances (PFAS) are environmentally persistent endocrine-disrupting chemicals associated with long-term health outcomes. PFAS are…”
Get full text
Journal Article -
16
Identification of Furan Metabolites Derived from Cysteine−cis-2-Butene-1,4-dial−Lysine Cross-Links
Published in Chemical research in toxicology (18-01-2010)“…Furan is a rodent hepatotoxicant and carcinogen. Because this compound is an important industrial intermediate and has been detected in heat-processed foods…”
Get full text
Journal Article -
17
Acrolein Increases the Pulmonary Tumorigenic Activity of the Tobacco-Specific Nitrosamine 4‑(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
Published in Chemical research in toxicology (17-10-2022)“…Tobacco smoke is a complex mixture of more than 7000 chemicals, of which many are toxic and/or carcinogenic. Many hazard assessments of tobacco have focused on…”
Get full text
Journal Article -
18
Proton pump inhibitors and histamine 2 blockers are associated with improved overall survival in patients with head and neck squamous carcinoma
Published in Cancer prevention research (Philadelphia, Pa.) (01-12-2014)“…It has been postulated that gastroesophageal reflux plays a role in the etiology of head and neck squamous cell carcinomas (HNSCC) and contributes to…”
Get full text
Journal Article -
19
Dietary and plasma carotenoids are positively associated with alpha diversity in the fecal microbiota of pregnant women
Published in Journal of food science (01-02-2021)“…Because microbes use carotenoids as an antioxidant for protection, dietary carotenoids could be associated with gut microbiota composition. We aimed to…”
Get full text
Journal Article -
20
Furan Metabolites Are Elevated in Users of Various Tobacco Products and Cannabis
Published in Chemical research in toxicology (20-02-2023)“…Humans are exposed to furan, a toxicant and possible human carcinogen, through multiple sources including diet and tobacco smoke. The urinary metabolites of…”
Get full text
Journal Article