Search Results - "Peterson, Laura S"
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Fibroblast-specific plasminogen activator inhibitor-1 depletion ameliorates renal interstitial fibrosis after unilateral ureteral obstruction
Published in Nephrology, dialysis, transplantation (01-12-2019)“…Plasminogen activator inhibitor-1 (PAI-1) expression increases extracellular matrix deposition and contributes to interstitial fibrosis in the kidney after…”
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2
Single-Cell Analysis of the Neonatal Immune System Across the Gestational Age Continuum
Published in Frontiers in immunology (23-08-2021)“…Although most causes of death and morbidity in premature infants are related to immune maladaptation, the premature immune system remains poorly understood. We…”
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3
A Peripheral Immune Signature of Labor Induction
Published in Frontiers in immunology (09-09-2021)“…Approximately 1 in 4 pregnant women in the United States undergo labor induction. The onset and establishment of labor, particularly induced labor, is a…”
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4
Leveraging Microbial Symbiosis to Modulate Bronchopulmonary Dysplasia
Published in American journal of respiratory cell and molecular biology (01-03-2023)“…More than a third of infants born at less than 28 weeks' gestation suffer from bronchopulmonary dysplasia (BPD), a chronic lung condition that results from…”
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5
Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset
Published in Science translational medicine (05-05-2021)“…Estimating the time of delivery is of high clinical importance because pre- and postterm deviations are associated with complications for the mother and her…”
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6
Perinatal infection, inflammation, preterm birth, and brain injury: A review with proposals for future investigations
Published in Experimental neurology (01-05-2022)“…Preterm newborns are exposed to several risk factors for developing brain injury. Clinical studies have suggested that the presence of intrauterine infection…”
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7
Multiomic immune clockworks of pregnancy
Published in Seminars in immunopathology (01-08-2020)“…Preterm birth is the leading cause of mortality in children under the age of five worldwide. Despite major efforts, we still lack the ability to accurately…”
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Differential Dynamics of the Maternal Immune System in Healthy Pregnancy and Preeclampsia
Published in Frontiers in immunology (11-06-2019)“…Preeclampsia is one of the most severe pregnancy complications and a leading cause of maternal death. However, early diagnosis of preeclampsia remains a…”
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9
Outcomes and Resource Use Among Overweight and Obese Children With Sepsis in the Pediatric Intensive Care Unit
Published in Journal of intensive care medicine (01-05-2020)“…Objective: To evaluate the effect of overweight and obesity on outcomes and resource use among patients with sepsis in the pediatric intensive care unit…”
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10
Human metapneumovirus small hydrophobic (SH) protein downregulates type I IFN pathway signaling by affecting STAT1 expression and phosphorylation
Published in Virology (New York, N.Y.) (01-07-2016)“…Abstract Type I interferon (IFN) is a key mediator of antiviral immunity. Human metapneumovirus (HMPV) inhibits IFN signaling, but does not encode homologues…”
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Understanding how biologic and social determinants affect disparities in preterm birth and outcomes of preterm infants in the NICU
Published in Seminars in perinatology (01-06-2021)“…To understand the disparities in spontaneous preterm birth (sPTB) and/or its outcomes, biologic and social determinants as well as healthcare practice (such as…”
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12
Effectiveness of a School-Based Deworming Campaign in Rural Kenya
Published in Journal of tropical pediatrics (1980) (01-12-2011)“…In 2007, the rate of intestinal helminth infection in primary school-aged children in a rural village in Southwestern Kenya was estimated to be at least 68%,…”
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13
Data-Driven Modeling of Pregnancy-Related Complications
Published in Trends in molecular medicine (01-08-2021)“…A healthy pregnancy depends on complex interrelated biological adaptations involving placentation, maternal immune responses, and hormonal homeostasis. Recent…”
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Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19
Published in Cell reports. Medicine (19-07-2022)“…The biological determinants underlying the range of coronavirus 2019 (COVID-19) clinical manifestations are not fully understood. Here, over 1,400 plasma…”
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Pediatric Collaborative Networks for Quality Improvement and Research
Published in Academic pediatrics (01-11-2013)“…Abstract Despite efforts of individual clinicians, pediatric practices, and institutions to remedy continuing deficiencies in pediatric safety and health care…”
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Effect of Acute Fatigue of the Hip Abductors on Control of Balance in Young and Older Women
Published in Archives of physical medicine and rehabilitation (01-07-2009)“…Abstract Bellew JW, Panwitz BL, Peterson L, Brock MC, Olson KE, Staples WH. Effect of acute fatigue of the hip abductors on control of balance in young and…”
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Risk Factors for Unanticipated Readmissions during the Interstage: A Report from the National Pediatric Cardiology Quality Improvement Collaborative
Published in Seminars in thoracic and cardiovascular surgery (2016)“…Objective This study describes unanticipated interstage readmissions in patients with hypoplastic left heart syndrome, identifies independent risk factors for…”
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